Neutron capture therapy system
US-2019224499-A1 · Jul 25, 2019 · US
US12167953B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12167953-B2 |
| Application number | US-202217974648-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 27, 2022 |
| Priority date | Nov 23, 2020 |
| Publication date | Dec 17, 2024 |
| Grant date | Dec 17, 2024 |
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An animal irradiation system includes a radioactive source and an irradiation fixing apparatus having irradiated bodies. The radioactive source includes a beam outlet having a first central axis. Radioactive rays generated by the radioactive source exit from the beam outlet and irradiate the irradiated bodies. The radioactive rays define a main axis around the first central axis. The irradiation fixing apparatus includes a box body, which is divided into multiple accommodating chambers around a second central axis. Each accommodating chamber accommodates an irradiated body. Multiple first irradiation holes corresponding to the accommodating chambers are formed on the box body. The radioactive rays pass through the first irradiation holes and then irradiate the irradiated bodies. A maximum distance from an inner wall of each first irradiation hole to the first central axis is less than a minimum distance from an inner wall of the beam outlet to the first central axis.
Opening claim text (preview).
What is claimed is: 1. An animal irradiation system comprising: a radioactive source and an irradiation fixing apparatus; wherein the radioactive source comprises: a beam outlet, from which radioactive rays generated by the radioactive source are irradiated to a plurality of irradiated bodies in the irradiation fixing apparatus, and wherein the irradiation fixing apparatus comprises: a box body configured to accommodate the irradiated bodies, wherein the box body is divided into a plurality of accommodating chambers, each of the plurality of accommodating chambers is configured to accommodate a corresponding one of the irradiated bodies, the irradiation fixing apparatus further comprises an irradiated body fixing part, the irradiated body fixing part is detachably installed in one of the accommodating chambers and positioned relative to the corresponding accommodating chamber, wherein the irradiated body fixing part is a fixing tube comprising a tube body and a fixing means, wherein the tube body is provided to accommodate the irradiated body, and the fixing means is provided to fix the irradiated body in the tube body. 2. The animal irradiation system according to claim 1 , wherein the beam outlet comprises a first central axis and defines a main axis around the first central axis, wherein the irradiation fixing apparatus further comprises a plurality of first irradiation holes arranged on the box body, wherein the box body has a second central axis and is circumferentially separated into a plurality of accommodating chambers around the second central axis, each of the accommodating chambers is configured to accommodate the corresponding one of the irradiated bodies, each of the plurality of first irradiation holes is corresponding to one of the accommodating chambers, the radioactive rays generated by the radioactive source irradiate the corresponding one of the irradiated bodies in each of the accommodating chambers through a corresponding one of the first irradiation holes, and a maximum distance from inner walls of the first irradiation holes to the first central axis is smaller than a minimum distance from an inner wall of the beam outlet to the first central axis. 3. The animal irradiation system according to claim 2 , wherein a second irradiation hole is provided in the tube body, and the radioactive rays generated by the radioactive source irradiates the irradiated bodies through the first and second irradiation holes. 4. The animal irradiation system according to claim 3 , wherein the fixing means comprises a fixing sleeve and a locking means provided in the tube body, the fixing sleeve is configured to fix a preset part of the irradiated bodies, the fixing sleeve is able to move in the tube body and is fixed by the locking means. 5. The animal irradiation system according to claim 2 , wherein the second central axis coincides with the first central axis, a plurality of the accommodating chambers are uniformly distributed circumferentially around the second central axis, the first irradiation holes have a same arrangement with the accommodating chambers, and the distances from the plurality of the first irradiation holes to the second central axis are equal. 6. The animal irradiation system according to claim 2 , wherein each of the first irradiation holes has a third central axis, and a distance between the inner wall of the first irradiation hole and the third central axis gradually decreases along a direction of the radioactive rays. 7. The animal irradiation system according to claim 6 , wherein the third central axis is parallel to the second central axis. 8. The animal irradiation system according to claim 1 , wherein the irradiation fixing apparatus is made of organic glass material or transparent material or with a hollow structure, wherein the hollow structure is filled with neutron shielding material or photon shielding material. 9. The animal irradiation system according to claim 1 , wherein the irradiation fixing apparatus is fixed with respect to the radioactive source. 10. The animal irradiation system according to claim 1 , wherein the radioactive source comprises: a neutron generating device configured to generate a neutron beam and form the beam outlet, the neutron beam coming out of the beam outlet irradiates the irradiated bodies in the irradiation fixing apparatus; and an irradiation fixing apparatus detachably connected to the beam outlet. 11. The animal irradiation system according to claim 10 , wherein the radioactive source also comprises a beam shaper or a collimator, wherein the beam shaper is configured to adjust beam quality of the neutron beam, the collimator is configured to converge the neutron beam, the neutron beam generated by the neutron generating device is irradiated to the irradiated bodies in the irradiation fixing apparatus through the beam shaper or the collimator, the beam shaper or the collimator forms the beam outlet, and the irradiation fixing apparatus is detachably connected to the beam shaper or the collimator. 12. The animal irradiation system according to claim 10 , wherein the neutron generating device comprises an accelerator and a target, wherein the accelerator is configured to accelerate protons and generate a proton line, and the proton line irradiates the target and interacts with the target to generate neutrons. 13. The animal irradiation system according to claim 10 , wherein the beam outlet comprises a first central axis and defines a main axis around the first central axis, the irradiation fixing apparatus comprises a box body configured to accommodate the irradiated bodies and a plurality of first irradiation holes arranged on the box body, wherein the box body comprises a second central axis and is circumferentially separated into a plurality of accommodating chambers around the second central axis, each of the accommodating chambers is configured to accommodate a corresponding one of the irradiated bodies, wherein each of the plurality of first irradiation holes is corresponding to one of the accommodating chambers, the radioactive rays generated by the radioactive source irradiate the corresponding one of the irradiated bodies in each of the accommodating chambers through a corresponding one of the first irradiation holes, and a maximum distance from inner walls of the first irradiation holes to the first central axis is smaller than a minimum distance from an inner wall of the beam outlet to the first central axis. 14. The animal irradiation system according to claim 1 , wherein the box body comprises a base and a cover plate, the base comprises a bottom plate and separators, the separators are a plurality of protruding parts extending from the bottom plate or the cover plate along directions parallel to the second central axis and distributed circumferentially around the second central axis, and the box body is circumferentially divided into the plurality of the accommodating chambers by the separators around the second central axis. 15. The animal irradiation system according to claim 14 , wherein the first irradiation holes are circumferentially distributed around the second central axis and provided on one of the bottom plate and the cover plate, and the first irradiation holes extend through in a direction parallel to the second central axis to communicate with each of the accommodating chambers. 16. The animal irradiation system according to claim 15 , wherein the other one of the bottom plate and the cover plate is provided with vent holes penetrating in directions parallel to the second central axis.
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