Bioactive components conjugated to dissolvable substrates of microneedle arrays
US-10737083-B2 · Aug 11, 2020 · US
US12162192B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12162192-B2 |
| Application number | US-202217846611-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 22, 2022 |
| Priority date | Jun 22, 2022 |
| Publication date | Dec 10, 2024 |
| Grant date | Dec 10, 2024 |
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A directional air knife, components thereof, and associated methods. The air knife includes a housing that comprises an inlet opening which receives air under pressure into the housing along a first inlet axis. A chamber is defined within the housing and positioned to receive air that passes through the inlet opening along the first inlet axis. A discharge duct is defined by the housing and includes a discharge channel within the discharge duct. The discharge channel is in fluid communication with the chamber which receives the air under pressure. The housing defines an outlet opening through which the air under pressure passes out of the discharge duct. The discharge channel has a second central axis along which the air under pressure flows to the outlet opening and out of the housing. The second central axis is arranged with respect to the first inlet axis at a skew angle.
Opening claim text (preview).
What is claimed is: 1. A directional air knife for use in applying air to an edge of a film as the film is being formed, the directional air knife comprising a housing including an inlet opening for receiving air under pressure into the housing along a first inlet axis, a chamber defined within the housing and positioned to receive air passing through the inlet opening along the first inlet axis, a discharge duct defined by the housing and including a discharge channel within the discharge duct in fluid communication with the chamber for receiving the air under pressure and an outlet opening through which the air under pressure passes out of the discharge duct, the discharge channel having a second central axis along which the air under pressure flows to the outlet opening and out of the housing, the second central axis being arranged with respect to the first inlet axis at an angle that is neither parallel with nor at right angles to the first inlet axis. 2. The directional air knife as set forth in claim 1 , wherein the outlet opening lies in a plane parallel to the first inlet axis. 3. The directional air knife as set forth in claim 2 , wherein the housing includes first and second internal walls defining opposite sides of the discharge channel, the first and second internal walls each making an angle that is neither parallel with nor at right angles to the first inlet axis. 4. The directional air knife as set forth in claim 3 , wherein the housing includes an inlet portion containing the chamber, the inlet portion of the housing having laterally opposite end surfaces, the discharge duct projecting laterally outward from a projection of one of the opposite end surfaces of the inlet portion of the housing. 5. The directional air knife as set forth in claim 4 , wherein the outlet opening is elongate in a direction between the first and second internal walls. 6. The directional air knife as set forth in claim 1 , wherein the discharge channel opens into the chamber along a side of the chamber. 7. The directional air knife as set forth in claim 6 , wherein the discharge channel opens into the chamber at a location offset laterally from the inlet opening. 8. The directional air knife as set forth in claim 1 , wherein the chamber is defined in part by a rounded internal wall of the housing opposite the inlet opening. 9. The directional air knife as set forth in claim 8 , wherein a portion of the rounded wall transitions smoothly into an internal wall of the housing forming a side of the discharge channel. 10. The directional air knife as set forth in claim 1 , further comprising a baffle mounted on the housing and at least partially located in the discharge channel, the baffle being movable with respect to the housing for changing the direction of flow of the air under pressure passing through the discharge channel to the outlet opening. 11. A directional air knife for use in applying air to an edge of a film as the film is being formed, the directional air knife comprising a housing including an inlet opening for receiving air under pressure into the housing, a chamber defined within the housing and positioned to receive air passing through the inlet opening, a discharge duct defined by the housing and including a discharge channel within the discharge duct in fluid communication with the chamber for receiving the air under pressure and an outlet opening through which the air under pressure passes out of the discharge duct, the housing including an inlet portion containing the chamber, the discharge duct extending from the inlet portion, the inlet portion of the housing having laterally opposite end surfaces, the discharge duct projecting laterally outward from a projection of one of the opposite end surfaces of the inlet portion of the housing, a first of the end surfaces being located opposite of the inlet opening, the first end surface being curved to an intersection with the discharge duct. 12. The directional air knife as set forth in claim 11 , wherein the discharge duct is free of any portion projecting laterally outward from a projection of the other of the opposite end surfaces of the inlet portion of the housing. 13. The directional air knife as set forth in claim 12 , wherein the opposite end surfaces of the inlet portion of the housing intersect respective end surface planes, the end surface planes being parallel to each other and generally perpendicular to an inlet axis passing through the inlet opening, the discharge duct intersecting one of the end surface planes, but not the other of the end surface planes. 14. The directional air knife as set forth in claim 11 , wherein the outlet opening lies in a plane parallel to the inlet axis. 15. The directional air knife as set forth in claim 14 , wherein the housing includes first and second internal walls defining opposite sides of the discharge channel, the first and second internal walls each making an angle that is neither parallel with nor at right angles to the inlet axis. 16. The directional air knife as set forth in claim 15 , wherein the outlet opening is elongate in a direction between the first and second internal walls. 17. The directional air knife as set forth in claim 11 , wherein the discharge channel opens into the chamber along a side of the chamber. 18. The directional air knife as set forth in claim 17 , wherein the discharge channel opens into the chamber at a location offset laterally from the inlet opening. 19. The directional air knife as set forth in claim 11 , wherein the chamber is defined in part by a rounded internal wall of the housing opposite the inlet opening. 20. The directional air knife as set forth in claim 19 , wherein a portion of the rounded wall transitions smoothly into an internal wall of the housing forming a side of the discharge channel.
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