Devices and methods for extraction of analytes

Patent metadata

Field	Value
Publication number	US-12158403-B2
Application number	US-202218045640-A
Country	US
Kind code	B2
Filing date	Oct 11, 2022
Priority date	Oct 11, 2022
Publication date	Dec 3, 2024
Grant date	Dec 3, 2024

Abstract

Devices and methods for use in extraction procedures of analytes (organic and inorganic, including heavy metals) from matrices (e.g., complex matrices) in various fields (e.g., biological, clinical, chemical, environmental, toxicological, and forensic) are provided. The device can comprise a support structure acting as a rigid and stable support for extraction materials that can be inserted thereinto. The device can comprise a plurality of windows in the support structure through which the extraction materials can be exposed. The device can include two portions that can join together (e.g., using an interlocking system).

First claim

What is claimed is:

1. A device for extraction of one or more analytes from one or more matrices, the device comprising:
a first portion comprising a plurality of protrusions and a first section of a compartment configured to contain a magnetic stirrer; and
a second portion comprising a plurality of holes or grooves and a second section of the compartment configured to contain the magnetic stirrer,
the plurality of protrusions respectively corresponding to the plurality of holes or grooves to form an interlocking system to removably interlock the first portion and the second portion with each other to give a closed state of the device,
the device comprising a plurality of windows configured to have a plurality of extractive materials respectively disposed therewithin when the device is in the closed state,
the device further comprising the plurality of extractive materials respectively disposed within the plurality of windows,
each extractive material of the plurality of extractive materials being in a form of a planar membrane,
the device further comprising the magnetic stirrer disposed in the compartment,
one of the first portion or the second portion comprising a raised edge around each window of the plurality of windows,
the other of the first portion or the second portion comprising a depression, corresponding in size to the corresponding raised edge, around each window of the plurality of windows,
the plurality of windows comprising at least six windows,
the plurality of protrusions comprising at least eight protrusions,
the plurality of holes or grooves comprising at least eight holes,
a material of the first portion and a material of the second portion both being inert with respect to the one or more analytes and the one or more matrices,
a height of the device being no more than 3.5 centimeters (cm),
a maximum width of the device being no more than 3.5 cm,
a maximum thickness of the device being no more than 1.1 cm, and
a maximum width of each window of the plurality of windows being no more than 0.7 cm.

Assignees

• The Florida International Univ Board Of Trustees
• Univ Degli Studi “G Dannunzio” Chieti Pescara

Inventors

• Kabir Abuzar
• Furton Kenneth G
• Locatelli Marcello
• Tartaglia Angela

Classifications

• G01N1/38

  Diluting, dispersing or mixing samples · CPC title

• G01N2001/386

  Other diluting or mixing processes · CPC title

• G01N2001/381

  by membrane diffusion; Permeation tubes · CPC title

• G01N1/4005

  by transferring a selected component through a membrane · CPC title

• G01N1/405

  by adsorption or absorption · CPC title