Conducting reactions in Leidenfrost-levitated droplets
US-10774044-B2 · Sep 15, 2020 · US
US12157725B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12157725-B2 |
| Application number | US-202217893399-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 23, 2022 |
| Priority date | Jun 6, 2016 |
| Publication date | Dec 3, 2024 |
| Grant date | Dec 3, 2024 |
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The invention generally relates to conducting reactions in Leidenfrost-levitated droplets.
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What is claimed is: 1. A method for forming a reaction product, the method comprising conducting multiple reactions in multiple separate Leidenfrost-levitated droplets while maintaining a substantially constant volume of each of the multiple separate Leidenfrost-levitated droplets; and merging the multiple separate Leidenfrost-levitated droplets into a single common Leidenfrost-levitated droplet, thereby forming a reaction product within the single common Leidenfrost-levitated droplet. 2. The method of claim 1 , further comprising collecting the reaction product in the single common Leidenfrost-levitated droplet without evaporating the single common Leidenfrost-levitated droplet. 3. The method according to claim 2 , further comprising analyzing the reaction product. 4. The method according to claim 3 , wherein analyzing is by a mass spectrometry technique. 5. The method according to claim 3 , wherein maintaining the substantially constant volume comprises introducing droplets of a pure solvent or a respective reaction mixture to each of the multiple separate Leidenfrost-levitated droplets. 6. The method according to claim 5 , wherein a rate at which the droplets of the pure solvent or the respective reaction mixture are introduced to each of the multiple separate Leidenfrost-levitated droplets is dependent on an evaporation rate of each of the multiple separate Leidenfrost-levitated droplets. 7. The method according to claim 1 , wherein the multiple reactions are the same. 8. The method according to claim 1 , wherein the multiple reactions are different. 9. The method according to claim 1 , wherein the method is conducted without the use of surfactants. 10. The method according to claim 1 , wherein the multiple separate Leidenfrost-levitated droplets are maintained separately by physical barriers between the multiple separate Leidenfrost-levitated droplets. 11. The method according to claim 10 , wherein the multiple separate Leidenfrost-levitated droplets are merged by removing the physical barriers between the multiple separate Leidenfrost-levitated droplets.
by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups · CPC title
the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton · CPC title
Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone · CPC title
having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom · CPC title
containing six-membered aromatic rings · CPC title
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