Systems and methods for synthesizing a reaction product and increasing yield of the same

Patent metadata

Field	Value
Publication number	US-12157126-B2
Application number	US-202117183691-A
Country	US
Kind code	B2
Filing date	Feb 24, 2021
Priority date	Mar 25, 2020
Publication date	Dec 3, 2024
Grant date	Dec 3, 2024

Abstract

The invention generally relates to systems and methods for synthesizing a reaction product and increasing yield of the same. In certain aspects, the invention provides a multi-mode reaction system in which in a first mode one or more valves of the system are configured to cause reagents to flow from one or more reagent reservoirs of the system through one or more components of the system to generate a reaction product; and in a second mode the one or more valves are configured to change flow within the system such that the one or more reagent reservoirs are isolated from a remainder of the system and the generated reaction product and any remaining reactants are recycled back through the multi-mode reaction system to increase a yield of the reaction product.

First claim

What is claimed is:

1. A method of producing a reaction product,
using a multi-mode reaction system comprising a pneumatic sprayer, a pump, one or more reagent reservoirs, a first heated reaction chamber, a second cooled condenser chamber and one or more valves, the multi-mode reaction system having a first mode in which the pump and the one or more valves cause reagents to flow from one or more reagent reservoirs and through a pneumatic sprayer to generate a reaction product via microdroplet formation and thin film reactions and second mode in which the one or more valves change the reaction product and unreacted reagents flow within the multi-mode system, isolate the one or more reagent reservoirs from other remaining sections of the multi-mode system and recycle the reaction product and the unreacted reagents back through the multi-mode reaction system to increase a yield of the reaction;
the method comprising:
with the one or more valves in the first mode, generating a reaction product via microdroplet formation and thin film reactions by flowing the reagents from the one or more reagent reservoirs through the pneumatic sprayer and into the first heated reaction chamber;
condensing the reaction product and the unreacted reagents in the second cooled condenser chamber by flowing the reaction product and the unreacted reagents from the first heated reaction chamber into the second cooled condenser chamber;
changing the reaction product and the unreacted reagents flow within the multi-mode system and isolating the one or more reagent reservoirs from the other sections of the multi-mode system by switching the one or more valves from the first mode to the second mode; and
with the one or more valves in the second mode, increasing the yield of the reaction by recycling the reaction product and the unreacted reactant back through the pneumatic sprayer, the first heated reaction chamber and the second cooled condenser chamber by causing the reaction product and the unreacted reactants to flow back from the second cooled condenser chamber and through the pneumatic sprayer.

2. The method of claim 1 , wherein the one or more valves comprises a first valve and a second valve wherein the first valve is disposed between the one or more reagent reservoirs and a pump and the second valve is disposed between the pneumatic sprayer and the pump.

3. The method of claim 2 , wherein in the first mode, the first valve is open and the second valve is closed.

4. The method of claim 2 , wherein, in the second mode, the second valve is open and the first valve is closed.

5. The method of claim 2 , wherein the generating the reaction product via microdroplet formation and thin film reactions comprises producing droplets of the reagents in a first reaction reservoir by producing a pneumatic spray of the reagents in the first reaction reservoir with the multi-mode reaction system further comprising the first reaction reservoir and a channel coupled to a gas line, the channel located after the pump, the channel configured to produce a pneumatic spray of the reagents into the first reaction reservoir to thereby produce droplets of the reagents in the first reaction reservoir, wherein a reaction rate of the reagents within the droplets in the first reaction reservoir is greater than a reaction rate of the reagents under a bulk state, wherein in the bulk state no droplets are formed.

6. The method of claim 1 , wherein the increasing the reaction yield of the reaction is performed with the multi-mode reaction system comprising a second reaction reservoir and a channel operably coupled to a second valve of the one or more valves and by flowing the reaction product and the unreacted reactants from the second reaction reservoir and through the channel operably coupled to the second valve and back through the pump, wherein the second valve is in an open position and a first valve of the one or more valves is in a closed condition.

7. The method of claim 1 , wherein the generating the reaction product via microdroplet formation and thin film reactions is performed with the reagents in a single reaction reservoir.

8. The method of claim 7 , wherein the generating the reaction product via microdroplet formation and thin film reactions is performed with the reagents in multiple reaction reservoirs.

Assignees

• Purdue Research Foundation

Inventors

• Cooks Robert Graham
• Wei Zhenwei

Classifications

• B01L2300/087

  Multiple sequential chambers · CPC title

• B01L2400/0487

  fluid pressure, pneumatics · CPC title

• B01L2300/1894

  Cooling means; Cryo cooling · CPC title

• B01L7/02

  Water baths; Sand baths; Air baths · CPC title

• B01J2204/002

  the feeding side being of particular interest · CPC title