Low-profile intercranial device

Patent metadata

Field	Value
Publication number	US-12150858-B2
Application number	US-202117357115-A
Country	US
Kind code	B2
Filing date	Jun 24, 2021
Priority date	Sep 4, 2015
Publication date	Nov 26, 2024
Grant date	Nov 26, 2024

Abstract

Provided is a functional, low-profile intercranial device (LID). The LID includes a base portion; at least one cavity associated with the base portion and configured to accept at least one functional component; and at least one conduit having a first end in communication with the at least one cavity. The at least one functional component includes a medicinal, electronic, or optic therapeutic. The at least one conduit is configured to accept the medicinal therapeutic and a second end configured to dispense the therapeutic.

First claim

What is claimed is:

1. A functional, low-profile intercranial device (LID), comprising:
a base portion comprising a cranial or craniofacial implant having a geometry that is configured to conform with a resected portion of a skull of a patient and has a thickness configured to provide strategic bulking for concomitant temporal hollowing correction, the base portion including a curvature specific to that of the skull to ensure a fit with absence of gaps along a periphery of the base portion, and the base portion being configured to address a patient clinical care algorithm both from a skull bone perspective and from an underlying regional brain perspective such that the cranial or craniofacial implant is configured to correct deformities and/or defects by placement at least partially within the resected portion of the skull during a surgical procedure to replace missing bone and provide cerebral protection from injury;
at least one functional component;
at least one cavity formed within the base portion as a void space within the base portion, the at least one cavity configured to encase the at least one functional component; and at least one conduit comprising an end configured to be in communication with the at least one cavity, wherein an orientation of at least one of the at least one conduit or the at least one functional component is configured to be customizable for the patient.

2. The functional, low-profile intercranial device of claim 1 , wherein the conduit is configured to provide for transit of a therapeutic from a functional component, of the at least one functional component, to a brain of the patient.

3. The functional, low-profile intercranial device claim 1 , wherein the conduit is configured to provide for transit of computer-guided responsive stimulation from a functional component, of the at least one functional component, to a brain of the patient.

4. The functional, low-profile intercranial device of claim 1 , wherein the at least one functional component is detachably connected to the base portion.

5. The functional, low-profile intercranial device of claim 1 , wherein the conduit is configured to provide for transit of signals from a functional component, of the at least one functional component, to a brain of the patient.

6. The functional, low-profile intercranial device of claim 1 , wherein the cranial or craniofacial implant is radiolucent.

7. The functional, low-profile intercranial device of claim 1 , wherein the cranial or craniofacial implant comprises polymethylmethacrylate (PMMA), polyether ether ketone (PEEK), or polyethylene.

8. The functional, low-profile intercranial device of claim 1 , wherein the cranial or craniofacial implant is a custom cranial or craniofacial implant.

9. A functional intercranial implant, comprising:
a base portion comprising a cranial or craniofacial implant having (i) a first portion with a geometry that is configured to conform with a resected portion of a skull of a patient to ensure a fit with absence of gaps along a periphery of the base portion and (ii) a second portion of increased thickness configured to provide strategic bulking for concomitant temporal hollowing correction, the second portion having space for accommodating a functional component, the cranial or craniofacial implant being configured to address a patient clinical care algorithm both from a skull bone perspective and from an underlying regional brain perspective such that the cranial or craniofacial implant is configured to correct deformities and/or defects by placement at least partially within the resected portion of the skull during a surgical procedure to replace missing bone and provide cerebral protection from injury; and
a conduit comprising an end configured to be in communication with the functional component, an orientation of at least the conduit or the functional component being configurable to be customizable for the patient.

10. The functional intercranial implant of claim 9 , wherein the functional component is configured to deliver a medicinal therapeutic.

11. The functional intercranial implant of claim 10 , wherein the end is a first end configured to be in communication with the functional component to accept the medicinal therapeutic, and wherein the conduit further comprising a second end configured to dispense the medicinal therapeutic.

12. The functional intercranial implant of claim 9 , wherein the conduit is configured to provide for transit of a therapeutic.

13. The functional intercranial implant of claim 9 , wherein the conduit is configured to provide for transit of computer-guided responsive stimulation from the functional component.

14. The functional intercranial implant of claim 9 , wherein the conduit is configured to provide for transit of signals from the functional component to a brain of the patient.

15. The functional intercranial implant of claim 9 , wherein the cranial or craniofacial implant is radiolucent.

16. The functional intercranial implant of claim 9 , wherein the cranial or craniofacial implant comprises polymethylmethacrylate (PMMA).

17. The functional intercranial implant of claim 9 , wherein the cranial or craniofacial implant is a custom cranial or craniofacial implant.

18. The functional intercranial implant of claim 9 , wherein the first portion has a thickness of around 4-12 millimeters.

19. The functional intercranial implant of claim 9 , wherein the functional component is a medicinal pump.

20. The functional intercranial implant of claim 9 , wherein the base portion comprises at least one porous surface through which a syringe needle can penetrate or at least one access port for accepting the syringe needle.

Assignees

• Univ Johns Hopkins

Inventors

• Gordon Chad

Classifications

• A61B5/37

  Intracranial electroencephalography [IC-EEG], e.g. electrocorticography [ECoG] · CPC title

• A61F2002/30948

  using computerized tomography, i.e. CT scans · CPC title

• A61F2/482

  Electrical means · CPC title

• A61B5/0036

  including treatment, e.g., using an implantable medical device, ablating, ventilating · CPC title

• G06T2207/20128

  Atlas-based segmentation · CPC title