Transcatheter heart valve prostheses

Patent metadata

Field	Value
Publication number	US-12144728-B2
Application number	US-202117540304-A
Country	US
Kind code	B2
Filing date	Dec 2, 2021
Priority date	Dec 7, 2020
Publication date	Nov 19, 2024
Grant date	Nov 19, 2024

Abstract

Transcatheter aortic valve prostheses for improving the cardiac function of a patient suffering from coronary artery disease. Transcatheter aortic valve prostheses include a valve component and a frame. The valve component includes valve leaflets and a skirt. The frame includes access cells that improve access to a patient's coronary arteries if further intervention is required and/or includes a window or conduction protection cell that is oriented to align with a portion of conduction system of the heart in situ to reduce conduction disturbances of the anatomy. Suture patterns for attaching a commissure to a commissure post of the frame, and for attaching a tissue bumper to the commissure post, are also described.

First claim

The invention claimed is:

1. A transcatheter aortic valve prosthesis for replacement of a native heart valve, the transcatheter aortic valve prosthesis comprising:
a frame having a plurality of struts, a plurality of crowns at an inflow end, a plurality of crowns at an outflow end, a plurality of commissure posts or commissure cells, a plurality of first cells, and at least one access cell, wherein the frame includes a row of the plurality of struts which includes a plurality of standard struts and a plurality of optimized struts, each standard strut of the plurality of standard struts having a first width profile and a first length, and each optimized strut of the plurality of optimized struts having a width profile that is different from the first width profile and a length that is different from the first length; and
a valve component including two or more valve leaflets disposed within the frame, wherein a commissure is formed where two valve leaflets of the two or more valve leaflets are attached to each other and each commissure is secured to a commissure post or commissure cell of the plurality of commissure posts or commissure cells of the frame, and
wherein an area of a first cell directly adjacent to the at least one access cell has a first area and the at least one access cell has a second area, the second area being at least twice as large as the first area, and
wherein the at least one access cell is centered in a circumferential direction between two commissure posts or commissure cells of the plurality of commissure posts or commissure cells of the frame, and
wherein the row of the plurality of struts which includes the plurality of standard struts and the plurality of optimized struts is disposed at an inflow end or an outflow end of the at least one access cell, and
wherein the frame includes at least three rows of struts between the inflow end of the frame and the inflow end of the at least one access cell.

2. A transcatheter aortic valve prosthesis for replacement of a native heart valve, the transcatheter aortic valve prosthesis comprising:
a frame having a plurality of struts, a plurality of crowns at an inflow end, a plurality of crowns at an outflow end, a plurality of commissure posts or commissure cells, a plurality of first cells, and at least one access cell, wherein the frame includes a row of the plurality of struts which includes a plurality of standard struts and a plurality of optimized struts, each standard strut of the plurality of standard struts having a first width profile and a first length, and each optimized strut of the plurality of optimized struts having a width profile that is different from the first width profile and a length that is different from the first length; and
a valve component including two or more valve leaflets disposed within the frame, wherein a commissure is formed where two valve leaflets of the two or more valve leaflets are attached to each other and each commissure is secured to a commissure post or commissure cell of the plurality of commissure posts or commissure cells of the frame, and
wherein an area of a first cell directly adjacent to the at least one access cell has a first area and the at least one access cell has a second area, the second area being at least twice as large as the first area, wherein the first area is approximately 25% of the second area, and
wherein the at least one access cell is centered in a circumferential direction between two commissure posts or commissure cells of the plurality of commissure posts or commissure cells of the frame, and
wherein the row of the plurality of struts which includes the plurality of standard struts and the plurality of optimized struts is disposed at an inflow end or an outflow end of the at least one access cell.

3. The transcatheter aortic valve prosthesis of claim 2 , wherein the plurality of optimized struts include a first optimized strut, a second optimized strut, a third optimized strut, and a fourth optimized strut, and wherein the first optimized strut and the second optimized strut enclose a portion of the at least one access cell, and wherein the third optimized strut is disposed directly adjacent to the first optimized strut and the fourth optimized strut is disposed directly adjacent to the second optimized strut.

4. The transcatheter aortic valve prosthesis of claim 2 , wherein the row of the plurality of struts which includes the plurality of standard struts and the plurality of optimized struts is a first row and the first row is disposed at the inflow end of the at least one access cell, and wherein the frame also includes a second row of the plurality of struts which includes the plurality of standard struts and the plurality of optimized struts and the second row is disposed at the outflow end of the at least one access cell.

5. The transcatheter aortic valve prosthesis of claim 2 , wherein the frame includes exactly three access cells and exactly three commissure cells.

6. The transcatheter aortic valve prosthesis of claim 2 , wherein the frame includes exactly three access cells and each access cell is disposed in a circumferential direction between two first cells.

7. The transcatheter aortic valve prosthesis of claim 1 , wherein the first area is approximately 33% of the second area.

8. The transcatheter aortic valve prosthesis of claim 1 , wherein the first area is approximately 14% of the second area.

9. The transcatheter aortic valve prosthesis of claim 1 , wherein the first area is approximately 12% of the second area.

10. The transcatheter aortic valve prosthesis of claim 1 , wherein the plurality of optimized struts include a first optimized strut, a second optimized strut, a third optimized strut, and a fourth optimized strut, and wherein the first optimized strut and the second optimized strut enclose a portion of the at least one access cell, and wherein the third optimized strut is disposed directly adjacent to the first optimized strut and the fourth optimized strut is disposed directly adjacent to the second optimized strut.

11. The transcatheter aortic valve prosthesis of claim 1 , wherein the row of the plurality of struts which includes the plurality of standard struts and the plurality of optimized struts is a first row and the first row is disposed at the inflow end of the at least one access cell, and wherein the frame also includes a second row of the plurality of struts which includes the plurality of standard struts and the plurality of optimized struts and the second row is disposed at the outflow end of the at least one access cell.

12. A transcatheter aortic valve prosthesis for replacement of a native heart valve, the transcatheter aortic valve prosthesis comprising:
a frame having a plurality of struts, a plurality of crowns at an inflow end, a plurality of crowns at an outflow end, a plurality of commissure posts or commissure cells, a plurality of first cells, and at least one access cell, wherein the frame includes a row of the plurality of struts which includes a plurality of standard struts and a plurality of optimized struts, each standard strut of the plurality of standard struts having a first width profile and a first length, and each optimized strut of the plurality of optimized struts having a width profile that is different from the first width profile and a length that is different from the first length; and
a valve component including two or more valve leaflets disposed within the frame, wherein a commissure is formed where two valve leaflets of the two or more valve leaflets are attached to each other and each commissure is secured to a commissure post or commissure cell of the plurality of commiss

Assignees

• Medtronic Inc

Inventors

• Baldwin Matthew
• Hallak Amy
• Bell Rodney
• Weston Matthew
• Darekar Yogesh
• Falk Wayne
• Martin David Michael
• Conerney Mike
• Nolan David
• Mcveigh Cahal
• Olney Karl
• Dunaway Jamie
• Fatemi Far Fatemeh

Classifications

• A61F2250/0037

  differing in height or in length · CPC title

• A61F2250/0036

  differing in thickness · CPC title

• A61F2250/0039

  differing in diameter · CPC title

• A61F2/2418 Primary

  Scaffolds therefor, e.g. support stents · CPC title