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Steroid derivative regulators, method for preparing the same, and uses thereof
US12139508B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12139508-B2 |
| Application number | US-201916969133-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 31, 2019 |
| Priority date | Feb 11, 2018 |
| Publication date | Nov 12, 2024 |
| Grant date | Nov 12, 2024 |
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- Title
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Abstract
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Steroid derivative regulators, a method for preparing the same, and uses thereof are described. Specifically, a compound of formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and uses thereof as a regulator the of GABA A receptor for treating depression, convulsion, Parkinson's disease, and nervous system diseases are described, wherein the substituents of the formula (I) are as defined in the description.
First claim
Opening claim text (preview).
What is claimed is: 1. A compound of or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical composition, comprising a therapeutically effective amount of the compound according to claim 1 , the stereoisomer thereof, or the pharmaceutically acceptable salt thereof, and one or more pharmaceutically acceptable carriers, diluents or excipients. 3. A method of treating depression or epilepsy in a subject in need thereof, comprising administering the pharmaceutical composition according to claim 2 to the subject.
Assignees
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Classifications
containing nitrile radicals, including thiocyanide radicals · CPC title
Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane · CPC title
by only one oxygen atom doubly bound · CPC title
Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane · CPC title
Drugs for disorders of the nervous system · CPC title
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- What does patent US12139508B2 cover?
- Steroid derivative regulators, a method for preparing the same, and uses thereof are described. Specifically, a compound of formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and uses thereof as a regulator the of GABA A receptor for treating depression, convulsion, Parkinson's disease, and nervous system diseases are described, wherein the substi…
- Who is the assignee on this patent?
- Jiangsu Hansoh Pharmaceutical Group Co Ltd, Shanghai Hansoh Biomedical Co Ltd
- What technology area does this patent fall under?
- Primary CPC classification C07J43/003. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Nov 12 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).