Lumen morphology and vascular resistance measurements data collection systems apparatus and methods

Patent metadata

Field	Value
Publication number	US-12138017-B2
Application number	US-202117508502-A
Country	US
Kind code	B2
Filing date	Oct 22, 2021
Priority date	Sep 23, 2009
Publication date	Nov 12, 2024
Grant date	Nov 12, 2024

Abstract

A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

First claim

The invention claimed is:

1. A method for identifying treatment options for stenotic lesions within a vessel, comprising:
providing for display, by one or more processors, a 3D representation of a vessel based on vessel image data, wherein the display of the 3D representation of the vessel includes an indication of vessel narrowing;
providing for display, by the one or more processors, a proximal location indicator and a distal location indicator, wherein the proximal location indicator is located proximally to the indication of vessel narrowing and the distal location indicator is located distally to the indication of vessel narrowing;
receiving, by the one or more processors, user input for controlling a position for at least one of the proximal location indicator or the distal location indicator;
simulating, by the one or more processors, widening the vessel between the proximal location indicator and the distal location indicator by altering at least one of a 3D computational model or a resistance model; and
providing for display, by the one or more processors, an indication of at least one of vascular resistance or pressure based on simulating the widening of the vessel.

2. The method of claim 1 , wherein the indication of vessel narrowing identifies a minimum lumen area in connection with the 3D representation of the vessel.

3. The method of claim 1 , wherein the indication of at least one of vascular resistance or pressure comprises an indication of a resistance ratio within the vessel at a location proximal to the vessel narrowing and a location distal to the vessel narrowing.

4. The method of claim 1 , wherein the indication of at least one of vascular resistance or pressure comprises an indication of a pressure drop within the vessel.

5. The method of claim 1 , wherein providing for display the indication of at least one of vascular resistance or pressure further comprises providing for display a comparison of at least one of vascular resistance or pressure before and after simulating the widening of the vessel.

6. The method of claim 1 , wherein simulating widening of the vessel further comprises altering the 3D representation of the vessel.

7. The method of claim 6 , further comprising receiving, by the one or more processors, a user input for repositioning the stent within the 3D representation of the vessel.

8. A system for identifying treatment options for stenotic lesions within a vessel, comprising:
memory;
one or more processors in communication with the memory, the one or more processors configured to:
provide for display a 3D representation of a vessel based on vessel image data, wherein the display of the 3D representation of the vessel includes an indication of vessel narrowing;
provide for display a proximal location indicator and a distal location indicator, wherein the proximal location indicator is located proximally to the indication of vessel narrowing and the distal location indicator is located distally to the indication of vessel narrowing;
receive user input controlling position for at least one of the proximal location indicator or the distal location indicator;
simulate widening the vessel between the proximal location indicator and the distal location indicator by altering at least one of a 3D computational model or a resistance model; and
provide for display an indication of at least one of vascular resistance or pressure based on simulating the widening of the vessel.

9. The system of claim 8 , wherein the indication of vessel narrowing identifies a minimum lumen area in connection with the 3D representation of the vessel.

10. The system of claim 8 , wherein the indication of at least one of vascular resistance or pressure comprises an indication of a resistance ratio within the vessel at a location proximal to the vessel narrowing and a location distal to the vessel narrowing.

11. The system of claim 8 , wherein the indication of at least one of vascular resistance or pressure comprises an indication of a pressure drop within the vessel.

12. The system of claim 8 , wherein in providing for display the indication of at least one of vascular resistance or pressure the one or more processors are further configured to provide for display a comparison of at least one of vascular resistance or pressure before and after simulating the widening of the vessel.

13. The system of claim 8 , wherein simulating widening of the vessel further comprises altering the 3D representation of the vessel.

14. The system of claim 13 , wherein the one or more processors are further configured to receive a user input for repositioning the stent within the 3D representation of the vessel.

15. A non-transitory computer-readable medium storing instructions executable by one or more processors for performing a method of identifying treatment options for stenotic lesions within a vessel, comprising:
providing for display a 3D representation of a vessel based on vessel image data, wherein the display of the 3D representation of the vessel includes an indication of vessel narrowing;
providing for display a proximal location indicator and a distal location indicator, wherein the proximal location indicator is located proximally to the indication of vessel narrowing and the distal location indicator is located distally to the indication of vessel narrowing;
receiving user input controlling a position for at least one of the proximal location indicator or the distal location indicator;
simulating widening the vessel between the proximal location indicator and the distal location indicator by altering at least one of a 3D computational model or a resistance model; and
providing for display an indication of at least one of vascular resistance or pressure based on simulating the widening of the vessel.

16. The non-transitory computer-readable medium of claim 15 , wherein the indication of vessel narrowing identifies a minimum lumen area in connection with the 3D representation of the vessel.

17. The non-transitory computer-readable medium of claim 15 , wherein the indication of at least one of vascular resistance or pressure comprises an indication of a resistance ratio within the vessel at a location proximal to the vessel narrowing and a location distal to the vessel narrowing.

18. The non-transitory computer-readable medium of claim 15 wherein the indication of at least one of vascular resistance or pressure comprises an indication of a pressure drop within the vessel.

19. The non-transitory computer-readable medium of claim 15 , wherein providing for display the indication of at least one of vascular resistance or pressure further comprises providing for display a comparison of at least one of vascular resistance or pressure before and after simulating the widening of the vessel.

20. The non-transitory computer-readable medium of claim 15 , wherein simulating widening of the vessel comprises simulation of a stent, and further comprising receiving a user input for repositioning the stent within the 3D representation of the vessel.

Assignees

• Lightlab Imaging Inc

Inventors

• Schmitt Joseph M
• Friedman Joel M
• Petroff Christopher
• Elbasiony Amr

Classifications

• A61B5/0073

  by tomography, i.e. reconstruction of 3D images from 2D projections (A61B5/0066 takes precedence) · CPC title

• A61B5/0066

  Optical coherence imaging · CPC title

• A61B5/0084

  for introduction into the body, e.g. by catheters (A61B5/1459 takes precedence) · CPC title

• A61B5/02007 Primary

  Evaluating blood vessel condition, e.g. elasticity, compliance · CPC title