No-view interfraction treatment target motion management using volumetric imaging

Patent metadata

Field	Value
Publication number	US-12128252-B2
Application number	US-201815862461-A
Country	US
Kind code	B2
Filing date	Jan 4, 2018
Priority date	Jan 6, 2017
Publication date	Oct 29, 2024
Grant date	Oct 29, 2024

Abstract

A method of the present disclosure includes identifying, based on a reference image, a full motion range of a target, wherein the full motion range of the target defines a full internal target volume (ITV). The method further includes identifying a non-target object in a motion image or the reference image. The method further includes performing a volumetric alignment of the ITV and the non-target object. The method further includes modifying a non-target to target displacement vector based on the volumetric alignment. The method further includes tracking the target based on the modified non-target to target displacement vector.

First claim

What is claimed is:

1. A method, comprising:
identifying, based on a reference image, a full motion range of a target, wherein the full motion range of the target defines a full internal target volume (ITV), wherein the reference image is a four-dimensional (4D) inhale and exhale planning image;
identifying a non-target object in a motion image or the reference image;
determining, based on a volumetric alignment of the ITV and the non-target object, a non-target to target displacement vector between a reference point on the non-target object and a center of the target as defined by the reference image based on the volumetric alignment, wherein the non-target to target displacement vector defines an estimated relative position of the target with respect to the non-target object; and
applying, by a processing device, the same non-target to target displacement vector at the reference point on the non-target object after each of a plurality of non-target object corrections to perform 0-view tracking of the target indirectly based on the non-target to target displacement vector without tracking the target directly in the motion image, wherein the target displacement vector is to compensate for gross motion of the target within a treatment fraction; and
compensating for baseline shift between treatment fractions based on the ITV.

2. The method of claim 1 , further comprising compensating for at least one of:, a setup error, a change in patient anatomy, or an intrafraction respiratory motion and baseline shift, based on the ITV.

3. The method of claim 1 , wherein the 4D inhale and exhale planning image is one of: a kilovoltage computed tomography (kV-CT) image, a magnetic resonance imaging (MRI) image, a kilovoltage cone beam computed tomography (kV-CBCT) image, or a megavoltage computed tomography (MVCT) image.

4. The method of claim 1 further comprising performing the volumetric alignment of the ITV and the non-target object including: performing two independent rigid registrations using determined registration regions of interest (ROI), or by deformable registration.

5. The method of claim 1 , wherein the reference image or the motion image are generated by an imaging source of a helical radiation delivery system or by one or more imaging sources at different positions with respect to a patient.

6. A system comprising:
a memory; and
a processing device, operatively coupled with the memory, to:
identify, based on a reference image, a full motion range of a target, wherein the full motion range of the target defines a full internal target volume (ITV), wherein the reference image is a four-dimensional (4D) inhale and exhale planning image;
identify a non-target object in a motion image or the reference image;
determine, based on a volumetric alignment of the ITV and the non-target object, a non-target to target displacement vector between a reference point on the non-target object and a center of the target defined by the reference image based on the volumetric alignment, wherein the non-target to target displacement vector defines an estimated relative position of the target with respect to the non-target object;
apply the same non-target to target displacement vector at the reference point on the non-target object after each of a plurality of non-target object corrections to perform 0-view tracking of the target indirectly based on the non-target to target displacement vector without tracking the target directly in the motion image, wherein the target displacement vector is to compensate for gross motion of the target within a treatment fraction; and
compensate for baseline shift between treatment fractions based on the ITV.

7. The system of claim 6 , wherein the processing device is further to compensate for at least one of: a setup error, a change in patient anatomy, or an intrafraction respiratory motion and baseline shift, based on the ITV.

8. The system of claim 6 , wherein the 4D inhale and exhale planning image is one of: a kilovoltage computed tomography (kV-CT) image, a magnetic resonance imaging (MRI) image, a kilovoltage cone beam computed tomography (kV-CBCT) image, or a megavoltage computed tomography (MVCT) image.

9. The system of claim 6 , wherein the processing device is further to perform the volumetric alignment of the ITV and the non-target object including to: perform two independent rigid registrations using determined registration regions of interest (ROI), or by deformable registration.

10. The system of claim 6 , wherein the reference image or the motion image are generated by an imaging source of a helical radiation delivery system or by one or more imaging sources at different positions with respect to a patient.

11. A non-transitory computer readable medium comprising instructions that, when executed by a processing device, cause the processing device to:
identify, based on a reference image, a full motion range of a target, wherein the full motion range of the target defines a full internal target volume (ITV);
identify a non-target object in a motion image or the reference image, wherein the motion image is a four-dimensional (4D) inhale and exhale intrafraction image;
determine, based on a volumetric alignment of the ITV and the non-target object, a non-target to target displacement vector between a reference point on the non-target object and a center of the target as defined by the reference image based on the volumetric alignment, wherein the non-target to target displacement vector defines an estimated relative position of the target with respect to the non-target object;
apply, by the processing device, the same non-target to target displacement vector at the reference point on the non-target object after each of a plurality of non-target object corrections to perform 0-view tracking of the target indirectly based on the non-target to target displacement vector without tracking the target directly in the motion image, wherein the target displacement vector is to compensate for gross motion of the target within a treatment fraction; and
compensate for baseline shift between treatment fractions based on the ITV.

12. The non-transitory computer readable medium of claim 11 , wherein the processing device is further to compensate for at least one of: a setup error, a change in patient anatomy, or an intrafraction respiratory motion and baseline shift, based on the ITV.

13. The non-transitory computer readable medium of claim 11 , wherein the reference image is a four-dimensional (4D) or a three-dimensional (3D) inhale and exhale planning image, and wherein the 4D inhale and exhale planning image is one of: a kilovoltage computed tomography (kV-CT) image, a magnetic resonance imaging (MRI) image, a kilovoltage cone beam computed tomography (kV-CBCT) image, or a megavoltage computed tomography (MVCT) image.

14. The non-transitory computer readable medium of claim 11 , wherein the reference image is a three-dimensional (3D) planning image, and wherein the 3D planning image is one of: a kilovoltage computed tomography (kV-CT) image, a magnetic resonance imaging (MRI) image, a kilovoltage cone beam computed tomography (kV-CBCT) image, or a megavoltage computed tomography (MVCT) image.

15. The non-transitory computer readable medium of claim 11 , wherein the processing device is further to perform the volumetric alignment of the ITV and the non-target object including to: perform two independent rigid registrations using determined registration regions of interest (ROI), or by deformable registration.

16. The non-transitory computer readable medium of claim 11 , wherein

Assignees

• Accuray Inc

Inventors

• Jordan Petr
• Maurer Jr Calvin R

Classifications

• A61N5/107

  in real time, i.e. during treatment · CPC title

• A61N5/1083

  Robot arm beam systems · CPC title

• A61B6/50

  specially adapted for specific body parts; specially adapted for specific clinical applications · CPC title

• A61B6/486

  involving generating temporal series of image data · CPC title

• A61B6/032

  Transmission computed tomography [CT] · CPC title