Lactobacillus having various functions, and use thereof
US-11202811-B2 · Dec 21, 2021 · US
US12115200B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12115200-B2 |
| Application number | US-201917290516-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 30, 2019 |
| Priority date | Nov 2, 2017 |
| Publication date | Oct 15, 2024 |
| Grant date | Oct 15, 2024 |
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The present disclosure relates to Lactobacillus plantarum NK3 and Bifidobacterium longum NK49, which are novel lactic acid bacteria, and, more particularly, to a composition comprising novel lactic acid bacteria that are useful for the prevention or treatment of female menopausal disorders.
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The invention claimed is: 1. A method for treating a female menopausal disorder comprising administering to a subject in need thereof an effective amount of Bifidobacterium longum NK49 having the accession number KCCM12088P, wherein the subject is a female having a sign of loss of female reproductive function, and wherein the female menopausal disorder is at least one selected from the group consisting of depression, anxiety, obesity, and osteoporosis. 2. The method of claim 1 , wherein the method further comprises administering an effective amount of Lactobacillus plantarum NK3 having the accession number KCCM12089P. 3. The method of claim 1 , wherein the Bifidobacterium longum NK49 having the accession number KCCM12088P comprises a 16S rDNA sequence of SEQ ID NO: 2. 4. The method of claim 2 , wherein Lactobacillus plantarum NK3 having the accession number KCCM12089P comprises a 16S rDNA sequence of SEQ ID NO: 1. 5. The method of claim 1 , wherein the female menopausal disorder is osteoporosis, obesity, or depression. 6. The method of claim 1 , the Bifidobacterium longum NK49 having the accession number KCCM12088P is a live bacterial body thereof, a dead bacterial body thereof, a culture thereof, a lysate thereof, or an extract thereof. 7. The method of claim 2 , the Lactobacillus plantarum NK3 having the accession number KCCM12089P is a live bacterial body thereof, a dead bacterial body thereof, a culture thereof, a lysate thereof, or an extract thereof. 8. The method of claim 2 , wherein a ratio of mixture of Lactobacillus plantarum NK3 having the accession number KCCM12089P and Bifidobacterium longum NK49 having the accession number KCCM12088P is 1:1 to 4:1 CFU.
Bacteria; Culture media therefor · CPC title
for osteoporosis · CPC title
Antidepressants · CPC title
Anorexiants; Antiobesity agents · CPC title
Probiotics · CPC title
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