Occlusion resolution in medication delivery devices, systems, and methods

Patent metadata

Field	Value
Publication number	US-12106837-B2
Application number	US-202016802753-A
Country	US
Kind code	B2
Filing date	Feb 27, 2020
Priority date	Jan 14, 2016
Publication date	Oct 1, 2024
Grant date	Oct 1, 2024

Abstract

Methods, devices, and systems of delivering infusion fluid (e.g., medication such as insulin) can detect, at multiple times during a dispensation period of time, a pressure level of the infusion fluid in an infusion fluid pathway, either directly or indirectly. Based on the detected pressure levels, one or more actual dispensation times that are after an intended dispensation time can be determined. In some cases, methods, devices, and systems provided herein can use variable occlusion alarm thresholds, which can depend on variables such as an age of an infusion set and/or a current analyte level. In some cases, methods, devices, and systems provided herein can automate medication delivery and use the actual dispensation times in a control algorithm determining medication deliveries.

First claim

What is claimed is:

1. A method for detecting an occlusion in an automated medication delivery system comprising:
detecting at least one real-time analyte level for a user;
based at least partially on the detected at least one real-time analyte level, determining a variable pressure threshold;
determining a dosage of medication for delivery to the user based on the at least one real-time analyte level, wherein the dosage of medication is determined without user input;
initiating a dispensation of the determined dosage of the medication using a medication delivery device;
measuring a pressure of the medication in an infusion fluid pathway of the medication delivery device; and
initiating an occlusion alarm if the measured pressure exceeds the variable pressure threshold.

2. The method of claim 1 , wherein the variable pressure threshold is further dependent on a timing of one or more recent dispensations, amount of one or more recent dispensations, type of one or more recent dispensations, or a combination thereof.

3. The method of claim 1 , wherein the medication is insulin and the analyte levels are glucose levels.

4. The method of claim 1 , wherein measuring the pressure of the medication in the infusion fluid pathway of the medication delivery device comprises measuring the pressure of the medication in the infusion fluid pathway of the medication delivery device at multiple times during a dispensation period of time, the method further comprising:
comparing each of the pressure measurements detected at the multiple times during the dispensation period to the variable pressure threshold; and
determining, based on one or more of the detected pressure measurements exceeding the variable pressure threshold, that an intended dispensation did not enter the user.

5. The method of claim 1 , wherein measuring the pressure of the medication in the infusion fluid pathway of the medication delivery device comprises measuring the pressure of the medication in the infusion fluid pathway of the medication delivery device at multiple times during a dispensation period of time, the method further comprising:
comparing each of the pressure measurements detected at the multiple times during the dispensation period to the variable pressure threshold; and
indicating via an alert, based on one or more of the detected pressure measurements exceeding the variable pressure threshold, that the dispensation was delayed.

6. A method for detecting an occlusion in an automated medication delivery system comprising:
detecting at least one real-time analyte level for a user;
based at least partially on the detected at least one real-time analyte level, determining a variable pressure threshold;
determining a dosage of medication for delivery to the user based on the at least one real-time analyte level;
initiating a dispensation of the determined dosage of the medication using a medication delivery device;
measuring a pressure of the medication in an infusion fluid pathway of the medication delivery device; and
initiating an occlusion alarm if the measured pressure exceeds the variable pressure threshold.

7. The method of claim 6 , wherein the variable pressure threshold is further dependent on a timing of one or more recent dispensations, amount of one or more recent dispensations, type of one or more recent dispensations, or a combination thereof.

8. The method of claim 6 , wherein the medication is insulin and the analyte is glucose.

Assignees

• Bigfoot Biomedical Inc
• Insulet Corp

Inventors

• Mazlish Bryan
• Desborough Lane
• Raghunathan Ravi Shankar Rontala

Classifications

• A61M2230/201

  Glucose concentration · CPC title

• A61M2205/587

  Lighting arrangements · CPC title

• A61M2205/583

  by visual feedback · CPC title

• A61M2205/582

  by tactile feedback · CPC title

• A61M2205/581

  by audible feedback · CPC title