Agent delivery systems and methods of using the same

Patent metadata

Field	Value
Publication number	US-12102749-B2
Application number	US-202017135571-A
Country	US
Kind code	B2
Filing date	Dec 28, 2020
Priority date	Jan 6, 2020
Publication date	Oct 1, 2024
Grant date	Oct 1, 2024

Abstract

A medical device that includes an enclosure for storing an agent, an agitator positioned adjacent to or within the enclosure and configured to oscillate relative to the enclosure, and an outlet having a first end in fluid communication with the enclosure and a second end in fluid communication with a channel of a delivery tube. Oscillation of the agitator causes the agent to move toward the outlet.

First claim

We claim:

1. A medical device comprising:
an enclosure for storing an agent, the enclosure having an inlet and an outlet;
an agitator positioned within the enclosure between the inlet and the outlet, the agitator includes a diaphragm that is flexibly deformable and configured to oscillate between the inlet and the outlet of the enclosure; and
wherein the outlet includes a first end in fluid communication with the enclosure and a second end in fluid communication with a channel of a delivery tube;
wherein oscillation of the agitator below the inlet and above the outlet causes the agent to move away from the inlet and toward the outlet.

2. The medical device of claim 1 , wherein the enclosure is in fluid communication with a first pressure medium source via the inlet, wherein the first pressure medium source stores a first pressurized fluid, and the delivery tube is in fluid communication with a second pressurized medium source that stores a second pressurized fluid.

3. The medical device of claim 2 , wherein the enclosure receives the first pressurized fluid through the inlet such that the diaphragm is configured to oscillate in response to the enclosure receiving the first pressurized fluid at the inlet above the diaphragm; and
wherein the delivery tube receives the second pressurized fluid through the delivery tube such that the delivery tube is configured to deliver the agent received from the outlet through the delivery tube via the second pressurized fluid.

4. The medical device of claim 1 , wherein the enclosure is fluidly coupled to the first pressure medium source via a valve.

5. The medical device of claim 4 , wherein the valve is configured to permit delivery of the first pressurized fluid from the first pressure medium source to the enclosure in response to actuation of the valve.

6. The medical device of claim 5 , wherein the agitator is configured to oscillate relative to the enclosure in response to the enclosure receiving the first pressurized fluid from the first pressure medium source.

7. The medical device of claim 1 , wherein the agent includes a hemostatic powder.

8. The medical device of claim 1 , wherein the diaphragm is configured to flex between a plurality of positions when oscillating between the inlet and the outlet.

9. The medical device of claim 1 , wherein the outlet includes a valve.

10. The medical device of claim 1 , wherein the agitator includes the diaphragm and one or more walls that define a void, wherein at least one of the one or more walls is configured to move relative to the enclosure in response to movement of the diaphragm.

11. The medical device of claim 10 , wherein the diaphragm and the at least one of the one or more walls are configured to oscillate when the first pressurized fluid from the first pressurized medium source is received within the void via the inlet.

12. The medical device of claim 1 , further comprising a coupling rod and a wheel, wherein the coupling rod has a first end coupled to the wheel and a second end coupled to the agitator.

13. The medical device of claim 12 , wherein the coupling rod is configured to oscillate the agitator in response to the wheel rotating.

14. The medical device of claim 13 , wherein the wheel is coupled to a motor that is operable to rotate the wheel.

15. A medical device comprising:
an enclosure having an inlet and an outlet, the enclosure configured for storing an agent below the inlet and above the outlet; and
an agitator positioned within the enclosure below the inlet and above the outlet, wherein the agitator includes a diaphragm that is flexibly deformable and configured to create pressure change within the enclosure via oscillation of the agitator between the inlet and the outlet of the enclosure;
wherein the outlet includes a first end in fluid communication with the enclosure and a second end in fluid communication with a delivery tube; and
wherein in response to oscillation of the agitator between the inlet and the outlet, the agent is moved away from the inlet and towards the outlet for receipt in the delivery tube, such that initiating a pressurized fluid propels the agent through the delivery tube.

16. The medical device of claim 15 , wherein the outlet is configured to control a dose of the agent outputted from the enclosure toward the delivery tube.

17. The medical device of claim 16 , wherein the agitator includes the diaphragm, one or more walls coupled to the diaphragm, and a void defined between the diaphragm and the one or more walls.

18. The medical device of claim 17 , wherein the diaphragm is configured to oscillate relative to the enclosure in response to the void receiving a pressurized medium and at least one of the one or more walls moving away from the diaphragm.

19. A method of delivering an agent to a target site via a medical device that includes an enclosure, an agitator, and a delivery tube, the method comprising:
delivering a first pressurized fluid into the enclosure via an inlet in response to actuating a first source of pressure, wherein the agitator is positioned within the enclosure relatively below the inlet such that the first pressurized fluid enters the enclosure above the agitator;
oscillating the agitator repeatedly between a plurality of positions relative to the enclosure to direct the agent stored within the enclosure away from the inlet and to an outlet of the enclosure that is in fluid communication with the delivery tube, wherein the agitator is positioned within the enclosure relatively above the outlet and oscillated in response to actuation of the first source of pressure that is in fluid communication with the enclosure; and
delivering the agent to the target site via the delivery tube with a second pressurized fluid entering the delivery tube, in response to actuation of a second source of pressure that is in fluid communication with the delivery tube.

20. The method of claim 19 , wherein the agitator includes a flexibly deformable diaphragm configured to flex upon the enclosure receiving the first pressurized fluid via the inlet.

Assignees

• Boston Scient Scimed Inc

Inventors

• Lehtinen Laurie
• Lydecker Lauren
• Pic Andrew
• Fredrickson Gerald
• Nam Ra

Classifications

• A61M2205/07

  having air pumping means · CPC title

• A61M2202/064

  Powder · CPC title

• A61M39/22

  Valves or arrangement of valves {(A61M39/02, A61M39/0247, A61M39/16 take precedence; regulating valves in infusion systems A61M5/16881; in devices worn by the patient for the reception of urine, faeces, catamenial or other discharge, or in colostomy devices A61F5/4405)} · CPC title

• A61B17/12186

  liquid materials adapted to be injected · CPC title

• A61B2017/12004

  for haemostasis, for prevention of bleeding · CPC title