Intradermal administration of immunoglobulin G preparation

US12091444B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12091444-B2
Application numberUS-202016805425-A
CountryUS
Kind codeB2
Filing dateFeb 28, 2020
Priority dateFeb 5, 2016
Publication dateSep 17, 2024
Grant dateSep 17, 2024

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A method for administration of an IgG preparation by an intradermal (ID) route to a subject includes loading with a volume of the IgG preparation an ID delivery device including needles, applying the device to a skin delivery site, using the device to allow dermal penetration of the needles, delivering the volume of the IgG preparation at the skin delivery site, and removing the injection delivery device. The method can be used in the treatment of a disease, such as an immunodeficiency.

First claim

Opening claim text (preview).

What is claimed is: 1. A method for treating a disease selected from the group consisting of an immunodeficiency, a disease of autoimmune origin, or combinations thereof in a subject in need thereof, the method comprising: administering a pooled human plasma-derived intravenous IgG antibody solution further comprising IgA and IgM to the subject using an ID delivery device comprising needles, wherein the ID delivery device is applied to a skin delivery site to allow dermal penetration of the needles such that the pooled human plasma-derived intravenous IgG antibody solution further comprising IgA and IgM is delivered at the skin delivery site, wherein the pooled human plasma-derived IVIG antibody preparation is about 2 mL to about 8 mL in volume with a pH of about 6.5, and has IgG concentration of about 16.5% to about 20% (w/v). 2. The method according to claim 1 , wherein the subject is a pediatric patient. 3. The method according to claim 1 , wherein the subject is a non-pediatric patient. 4. The method according to claim 1 , wherein the immunodeficiency is one of a primary immunodeficiency, a secondary immunodeficiency or an acquired immunodeficiency.

Assignees

Inventors

Classifications

  • Other apparatus for introducing media into the body (for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30); Percutany, i.e. introducing medicines into the body by diffusion through the skin (salt baths A61H33/04) · CPC title

  • A61K9/0021Primary

    Intradermal administration, e.g. through microneedle arrays or needleless injectors · CPC title

  • Medicinal preparations containing antigens or antibodies (materials for immunoassay G01N33/53) · CPC title

  • comprising antibodies · CPC title

  • characterised by the route of administration · CPC title

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What does patent US12091444B2 cover?
A method for administration of an IgG preparation by an intradermal (ID) route to a subject includes loading with a volume of the IgG preparation an ID delivery device including needles, applying the device to a skin delivery site, using the device to allow dermal penetration of the needles, delivering the volume of the IgG preparation at the skin delivery site, and removing the injection deliv…
Who is the assignee on this patent?
Grifols Worldwide Operations Ltd
What technology area does this patent fall under?
Primary CPC classification A61K9/0021. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Sep 17 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).