Immunoglobulin constant region Fc receptor binding agents
US-9926362-B2 · Mar 27, 2018 · US
US12091444B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12091444-B2 |
| Application number | US-202016805425-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 28, 2020 |
| Priority date | Feb 5, 2016 |
| Publication date | Sep 17, 2024 |
| Grant date | Sep 17, 2024 |
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Official abstract text for this publication.
A method for administration of an IgG preparation by an intradermal (ID) route to a subject includes loading with a volume of the IgG preparation an ID delivery device including needles, applying the device to a skin delivery site, using the device to allow dermal penetration of the needles, delivering the volume of the IgG preparation at the skin delivery site, and removing the injection delivery device. The method can be used in the treatment of a disease, such as an immunodeficiency.
Opening claim text (preview).
What is claimed is: 1. A method for treating a disease selected from the group consisting of an immunodeficiency, a disease of autoimmune origin, or combinations thereof in a subject in need thereof, the method comprising: administering a pooled human plasma-derived intravenous IgG antibody solution further comprising IgA and IgM to the subject using an ID delivery device comprising needles, wherein the ID delivery device is applied to a skin delivery site to allow dermal penetration of the needles such that the pooled human plasma-derived intravenous IgG antibody solution further comprising IgA and IgM is delivered at the skin delivery site, wherein the pooled human plasma-derived IVIG antibody preparation is about 2 mL to about 8 mL in volume with a pH of about 6.5, and has IgG concentration of about 16.5% to about 20% (w/v). 2. The method according to claim 1 , wherein the subject is a pediatric patient. 3. The method according to claim 1 , wherein the subject is a non-pediatric patient. 4. The method according to claim 1 , wherein the immunodeficiency is one of a primary immunodeficiency, a secondary immunodeficiency or an acquired immunodeficiency.
Other apparatus for introducing media into the body (for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30); Percutany, i.e. introducing medicines into the body by diffusion through the skin (salt baths A61H33/04) · CPC title
Intradermal administration, e.g. through microneedle arrays or needleless injectors · CPC title
Medicinal preparations containing antigens or antibodies (materials for immunoassay G01N33/53) · CPC title
comprising antibodies · CPC title
characterised by the route of administration · CPC title
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