Penicillin-G acylases
US-10865402-B2 · Dec 15, 2020 · US
Penicillin-G acylases
US12084697B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12084697-B2 |
| Application number | US-202318158339-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 23, 2023 |
| Priority date | Jan 5, 2017 |
| Publication date | Sep 10, 2024 |
| Grant date | Sep 10, 2024 |
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- Title
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- Abstract
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Abstract
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The present invention provides engineered penicillin G acylase (PGA) enzymes, polynucleotides encoding the enzymes, compositions comprising the enzymes, and methods of using the engineered PGA enzymes.
First claim
Opening claim text (preview).
We claim: 1. An engineered polynucleotide sequence encoding an engineered penicillin G acylase capable of acylating insulin, wherein the polypeptide sequence of said penicillin G acylase is at least 98%, 99% or more identical to SEQ ID NO:100. 2. The engineered polynucleotide sequence of claim 1 , wherein said sequence comprises a polynucleotide sequence that is at least 98%, 99% or more identical to SEQ ID NO: 99. 3. A vector comprising the polynucleotide sequence of claim 2 . 4. The vector of claim 3 , further comprising at least one control sequence. 5. A host cell comprising the vector of claim 3 .
Assignees
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Classifications
Penicillin amidase (3.5.1.11), i.e. penicillin-amidohydrolase · CPC title
Insulins · CPC title
having a known sequence of two or more amino acids, e.g. glutathione · CPC title
containing a His-tag · CPC title
- C12N9/84Primary
Penicillin amidase {(3.5.1.11)} · CPC title
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Frequently asked questions
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- What does patent US12084697B2 cover?
- The present invention provides engineered penicillin G acylase (PGA) enzymes, polynucleotides encoding the enzymes, compositions comprising the enzymes, and methods of using the engineered PGA enzymes.
- Who is the assignee on this patent?
- Codexis Inc
- What technology area does this patent fall under?
- Primary CPC classification C12N9/84. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Sep 10 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).