Inhibitors of glucosylceramide degradation in the treatment of diseases of the motor units

US12083091B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12083091-B2
Application numberUS-202017036860-A
CountryUS
Kind codeB2
Filing dateSep 29, 2020
Priority dateApr 11, 2016
Publication dateSep 10, 2024
Grant dateSep 10, 2024

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

Inhibitors of glucosylceramide degradation, to pharmaceutical compositions containing same and to the use of same in the treatment of diseases of the motor units, such as amyotrophic lateral sclerosis.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method for the treatment of a disease of the motor units, wherein the disease is Amyotrophic Lateral Sclerosis (ALS), and wherein the method comprises administering to a patient in need thereof a pharmaceutical composition consisting of ambroxol and/or a pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable carrier. 2. The method according to claim 1 wherein the pharmaceutical composition is administered to the patient at a dose of 0.01 to 500 mg/kg of body weight/day. 3. The method according to claim 1 wherein the pharmaceutical composition is administered to the patient at a dose of 0.1 to 250 mg/kg of body weight/day.

Assignees

Inventors

Classifications

  • Drugs for disorders of the muscular or neuromuscular system · CPC title

  • not condensed and containing further heterocyclic rings, e.g. cromakalim · CPC title

  • Carboxylic acids, e.g. valproic acid (salicylic acid A61K31/60) · CPC title

  • only substituted in position 1, e.g. propipocaine, diperodon · CPC title

  • Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine {or methadone} · CPC title

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Frequently asked questions

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What does patent US12083091B2 cover?
Inhibitors of glucosylceramide degradation, to pharmaceutical compositions containing same and to the use of same in the treatment of diseases of the motor units, such as amyotrophic lateral sclerosis.
Who is the assignee on this patent?
Spedding Res Solutions, Univ Strasbourg, Inserm—Institut National De La Sante Et De La Rech Medicale
What technology area does this patent fall under?
Primary CPC classification A61K31/336. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Sep 10 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).