Method for unsealing an opening of a laboratory sample container, method for handling a laboratory sample container, laboratory apparatus and laboratory automation system

Patent metadata

Field	Value
Publication number	US-12078650-B2
Application number	US-201916295179-A
Country	US
Kind code	B2
Filing date	Mar 7, 2019
Priority date	Mar 26, 2018
Publication date	Sep 3, 2024
Grant date	Sep 3, 2024

Abstract

A method for unsealing an opening of a laboratory sample container containing a sample is presented. The opening is sealed by a closure attached to the laboratory sample container by an adhesive. An adhesive strength of the adhesive is lowerable by treatment. The method comprises treating the adhesive such that its adhesive strength is lowered and removing the closure from the laboratory sample container.

First claim

I claim:

1. A laboratory apparatus for unsealing an opening of a laboratory sample container containing a liquid sample, wherein the opening is sealed by a closure attached to the laboratory sample container by an adhesive, wherein an adhesive strength of the adhesive is lowerable by treatment, the laboratory apparatus comprising:
a UV radiation treater that during operation causes the a material of the adhesive to undergo an adhesive strength reduction through crosslinking, the UV radiation treater configured to impart radiation to the adhesive along a direction that is substantially perpendicular to a line between the adhesive and the liquid sample;
a remover comprising at least one roller receptacle and mover; and
a movement unit configured to convey the sample container containing the liquid sample to keep the opening in an upright position, as well as to place the sample container in contact with the remover such that during operation the remover attaches a take-up to the closure by another adhesive that has an adhesive strength such that an adhesive force between the take-up and the attached closure is higher than an adhesive force between the closure and the laboratory sample container such that the take-up with the attached closure is removed from the laboratory sample container while keeping the sample container in the upright position, wherein the at least one roller receptacle and mover are configured to supply the take-up by a roller tape and to move the roller tape with the take-up with the attached closure from the laboratory sample container.

2. The laboratory apparatus according to claim 1 , wherein the remover further comprises a sucker cooperative with the closure to effect a vacuum-based removal of the closure from the laboratory sample container.

3. A laboratory automation system for handling the laboratory sample container containing the liquid sample, the laboratory automation system comprising:
a sealer, wherein the sealer is configured to seal the opening of the laboratory sample container by attaching the closure to the laboratory sample container by the adhesive, wherein the adhesive strength of the adhesive is lowerable by treatment; and
a laboratory apparatus according to claim 1 .

4. The laboratory automation system according to claim 3 , wherein the sealer comprises at least one roller receptacle and mover, wherein the roller receptacle and mover of the sealer is configured to supply the closure by a roller tape of the sealer and to move the roller tape of the sealer with the closure to the opening of the laboratory sample container for the sealing.

5. The laboratory apparatus according to claim 1 , wherein the UV radiation treater further comprises a heat source.

6. The laboratory apparatus according to claim 1 , further comprising a holder placed on the movement unit to convey the laboratory sample container into selective cooperation with at least one of the treater and remover.

7. The laboratory apparatus according to claim 6 , wherein the holder is configured to circumferentially contain at least a lower portion of the laboratory sample container.

8. The laboratory apparatus according to claim 1 , wherein the UV radiation treater is angled to impart the radiation to the adhesive while not to the liquid sample.

Assignees

• Roche Diagnostics Operations Inc

Inventors

• Mueller Daniel

Classifications

• B01F25/00

  Flow mixers; Mixers for falling materials, e.g. solid particles (centrifugal mixers B04) · CPC title

• B23P19/00

  Machines for simply fitting together or separating metal parts or objects, or metal and non-metal parts, whether or not involving some deformation {(connecting metal parts or objects by metal-working procedures B21J, B23K)}; Tools or devices therefor so far as not provided for in other classes (hand tools in general B25) · CPC title

• G01N33/543

  with an insoluble carrier for immobilising immunochemicals · CPC title

• G01N21/77

  by observing the effect on a chemical indicator · CPC title

• B01L3/02

  Burettes; Pipettes · CPC title