Organic salt, hydroxy-radical sensor including same, and detection medium

Patent metadata

Field	Value
Publication number	US-12078644-B2
Application number	US-201917253507-A
Country	US
Kind code	B2
Filing date	Apr 18, 2019
Priority date	Jun 22, 2018
Publication date	Sep 3, 2024
Grant date	Sep 3, 2024

Abstract

An organic salt of the present disclosure contains terephthalic acid and at least one kind of primary alkylamine. An alkyl group constituting the primary alkylamine has 6 or more and 17 or less carbon atoms. The organic salt of the present disclosure can be used to detect a hydroxy radical contained in a gas, for example. The present disclosure provides: an organic salt that makes it possible to detect a hydroxy radical more easily as well as to detect a hydroxy radical generated in a living body; and a hydroxy-radical sensor adopting the organic salt.

First claim

The invention claimed is:

1. An organic salt comprising terephthalic acid and at least one kind primary alkylamine, wherein
an alkyl group constituting the primary alkylamine has 6 or more and 9 or less carbon atoms.

2. The organic salt according to claim 1 , wherein the alkyl group is a normal alkyl group.

3. The organic salt according to claim 1 , wherein the alkyl group has 8 or more carbon atoms.

4. The organic salt according to claim 1 , wherein the organic salt has a supramolecular crystal structure including a molecule of the primary alkylamine and a molecule of the terephthalic acid.

5. The organic salt according to claim 4 , wherein the supramolecular crystal structure has a void between the molecule of the primary alkylamine and the molecule of the terephthalic acid.

6. The organic salt according to claim 1 , wherein the organic salt is for detecting a hydroxy radical contained in a gas.

7. A hydroxy-radical sensor configured to detect a hydroxy radical contained in a gas, comprising:
an exposure unit that includes an organic salt and has a structure in which the organic salt can be in contact with the gas;
a light source configured to irradiate the organic salt of the exposure unit with ultraviolet light; and
a light detector configured to detect fluorescence generated from the organic salt by the irradiation with the ultraviolet light, wherein
the hydroxy-radical sensor detects the hydroxy radical contained in the gas based on the fluorescence detected by the light detector,
the organic salt comprises terephthalic acid and at least one primary alkylamine, and an alkyl group constituting the primary alkylamine has 6 or more and 17 or less carbon atoms.

8. The hydroxy-radical sensor according to claim 7 , wherein the exposure unit is detachable as a detection medium.

9. A detection medium configured to be used for detecting a hydroxy radical contained in a gas,
comprising the organic salt according to claim 1 and
having a structure configured so that the organic salt can be in contact with the gas and allow for detection of a hydroxy radical contained in the gas.

10. A method comprising:
exposing an organic salt to a gas to be tested for presence of hydroxy radical, the organic salt including terephthalic acid and at least one primary alkylamine;
irradiating the organic salt with light from a light source;
detecting with a light detector fluorescence generated from the organic salt by the irradiating of the organic salt; and
determining the presence of hydroxy radical in the tested gas based on the detected fluorescence,
wherein an alkyl group constituting the primary alkylamine has 6 or more and 17 or less carbon atoms.

Assignees

• Panasonic Corp
• Panasonic Holdings Corp

Inventors

• Hosokawa Teppei
• Tohnai Norimitsu

Classifications

• G01N21/6486

  Measuring fluorescence of biological material, e.g. DNA, RNA, cells (G01N21/6428 takes precedence) · CPC title

• C07C211/07 Primary

  containing one, two or three alkyl groups, each having the same number of carbon atoms in excess of three · CPC title

• C07C63/28

  Salts thereof · CPC title

• G01N2800/7009

  Oxidative stress · CPC title

• G01N33/50

  Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing (measuring or testing processes involving enzymes or microorganisms, compositions or test papers therefor; processes for forming such compositions, condition responsive control in microbiological or enzymological processes C12Q) · CPC title