Immunotherapeutic potential of modified lipooligosaccharides/lipid A

US12077793B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12077793-B2
Application numberUS-202117445708-A
CountryUS
Kind codeB2
Filing dateAug 23, 2021
Priority dateMar 7, 2013
Publication dateSep 3, 2024
Grant dateSep 3, 2024

How to read this patent

A practical reading order for non-experts. Skip the full description unless you need deep technical detail.

  1. Title

    What the patent document calls the invention.

  2. Abstract

    A short plain-language summary of the technical disclosure.

  3. Assignees and inventors

    Who owns or filed the patent and who is credited as inventor.

  4. Key dates

    Filing, priority, publication, and grant dates set the timeline.

  5. First independent claim

    The legal scope of protection — read this for what is actually claimed.

  6. CPC / IPC classifications

    Technology tags used to group this patent with similar filings.

  7. Citations and related patents

    Prior art links and similar publications in this corpus.

Abstract

Official abstract text for this publication.

Embodiments of the disclosure provide for unique lipooligosaccharide/lipid A-based mimetics for use as adjuvants. Methods of generating lipooligosaccharide/lipid A-based mimetics are provided that utilize recombinantly engineered bacteria to produce the mimetics, including, for example, addition of one or more particular enzymes such as acyltransferases, deacylases, phosphatases, or glycosyltransferases.

First claim

Opening claim text (preview).

What is claimed is: 1. A biosynthetic lipid polysaccharide compound of formula (I) or formula (II) or a salt thereof. 2. A kit, comprising one or both of the compounds of claim 1 . 3. The kit of claim 2 , further comprising one or both of an antigen and a pharmaceutically acceptable carrier.

Assignees

Inventors

Classifications

  • Phosphates; Phosphites; Polyphosphates · CPC title

  • Preparation of O-glycosides, e.g. glucosides {(polysaccharides and not substituted disaccharides C12P19/04, C12P19/12)} · CPC title

  • Preparation of nitrogen-containing carbohydrates · CPC title

  • Lipopolysaccharides; Lipid A; Monophosphoryl lipid A · CPC title

  • Lipopolysaccharides · CPC title

Patent family

Related publications grouped by family.

External sources

Frequently asked questions

Answers are generated from the same data shown on this page.

What does patent US12077793B2 cover?
Embodiments of the disclosure provide for unique lipooligosaccharide/lipid A-based mimetics for use as adjuvants. Methods of generating lipooligosaccharide/lipid A-based mimetics are provided that utilize recombinantly engineered bacteria to produce the mimetics, including, for example, addition of one or more particular enzymes such as acyltransferases, deacylases, phosphatases, or glycosyltra…
Who is the assignee on this patent?
Univ Maryland, Univ Washington
What technology area does this patent fall under?
Primary CPC classification C12P19/12. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Sep 03 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).