Covers for drug container piston arrays or piston nests and packages for cover and piston nest assemblies
US-2017348476-A1 · Dec 7, 2017 · US
US12059387B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12059387-B2 |
| Application number | US-202017017752-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 11, 2020 |
| Priority date | Sep 11, 2019 |
| Publication date | Aug 13, 2024 |
| Grant date | Aug 13, 2024 |
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A charge device is provided that includes a charge barrel having a charge. The charge barrel has an exit aperture and a flexible positioning device at the exit aperture. The charge is located inside the charge barrel. The charge barrel is adapted and arranged so that the charge is able to exit the charge barrel via the exit aperture.
Opening claim text (preview).
The invention claimed is: 1. A charge device comprising: a charge barrel having an exit aperture and a flexible positioning device at the exit aperture, wherein the flexible positioning device comprises an outer face with a top end, the flexible positioning device having a circumferential recess positioned in the outer face where the top end meets the charge barrel, and wherein, below the circumferential recess, the flexible positioning device has a thickest point after which the flexible positioning device tapers towards a lower end; and a charge located inside the charge barrel, wherein the charge barrel is adapted and arranged so that the charge is able to exit the charge barrel via the exit aperture. 2. The charge device of claim 1 , further comprising a plurality of the charge barrels. 3. The charge device of claim 1 , wherein the charge barrel further comprises a venting device adapted and arranged to allow gas to escape from the charge barrel as the charge exits the charge barrel through the exit aperture. 4. The charge device of claim 3 , wherein the venting device is a hole or a slot. 5. The charge device of claim 1 , wherein the charge barrel comprises a polymer. 6. The charge device of claim 1 , wherein the charge barrel has a length that is not more than 3 times a length of the charge. 7. The charge device of claim 1 , wherein the charge barrel is configured so that a distance of the charge from the exit aperture is not more than 4 times a length of the charge. 8. The charge device of claim 1 , wherein the flexible positioning device is an incomplete hollow prism or cylinder having one or more holes in a sidewall. 9. The charge device of claim 1 , wherein the flexible positioning device has an inner diameter that is smaller than an inner diameter of the charge barrel. 10. The charge device of claim 1 , further comprising a sterile container, wherein the charge barrel is located inside the sterile container. 11. The charge device of claim 1 , wherein the charge is selected from a group consisting of a plunger, a stopper, a seal, and a seal cap. 12. The charge device of claim 1 , wherein the charge comprises a material having a Young's modulus less than that of the charge barrel. 13. The charge device of claim 1 , wherein the charge comprises a thermoplastic elastomer. 14. The charge device of claim 1 , wherein the circumferential recess is configured to facilitate air flow and flexion of the positioning device. 15. A kit comprising: a charge device comprising a charge barrel and a charge, the charge barrel having an exit aperture and a flexible positioning device at the exit aperture, the charge being located inside the charge barrel, wherein the charge barrel is adapted and arranged so that the charge is able to exit the charge barrel via the exit aperture, and wherein the flexible positioning device comprises an outer face with a top end, the flexible positioning device having a circumferential recess positioned in the outer face where the top end meets the charge barrel, and wherein, below the circumferential recess, the flexible positioning device has a thickest point after which the flexible positioning device tapers towards a lower end; and a receptacle device comprising a receptacle barrel having a receptacle located inside it, wherein the receptacle has an entry aperture that is configured to receive the charge from the charge barrel through the entry aperture. 16. The kit of claim 15 , wherein one the receptacle is selected from a group consisting of a cartridge, a syringe, a syringe precursor, and a vial. 17. The kit of claim 15 , wherein the charge barrel further comprises a venting device adapted and arranged to allow gas to escape from the charge barrel as the charge exits the charge barrel through the exit aperture. 18. The kit of claim 15 , wherein the flexible positioning device has an exterior diameter, which is smaller than an interior diameter of the receptacle so that the flexible positioning device can be inserted into the receptacle. 19. The kit of claim 15 , wherein, when the charge is received in the receptacle through the entry aperture, the flexible positioning device has a top end having a vent channel that remains outside of the entry aperture of the receptacle. 20. A charge device comprising: a charge barrel having an exit aperture and a flexible positioning device at the exit aperture, wherein the flexible positioning device comprises an outer face with a top end, the flexible positioning device having a circumferential recess positioned in the outer face where the top end meets the charge barrel; a charge located inside the charge barrel, wherein the charge barrel is adapted and arranged so that the charge is able to exit the charge barrel via the exit aperture; and a venting device adapted and arranged to allow gas to escape from the charge barrel as the charge exits the charge barrel through the exit aperture, wherein the venting device is in the flexible positioning device and extends from a bottom end towards the top end and through the circumferential recess.
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