18F-tagged inhibitors of prostate specific membrane antigen (PSMA) and their use as imaging agents for prostate cancer

US12054458B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-12054458-B2
Application numberUS-202318186043-A
CountryUS
Kind codeB2
Filing dateMar 17, 2023
Priority dateSep 30, 2015
Publication dateAug 6, 2024
Grant dateAug 6, 2024

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  1. Title

    What the patent document calls the invention.

  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

    Technology tags used to group this patent with similar filings.

  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers and imaging agents for various disease states of prostate cancer.

First claim

Opening claim text (preview).

The invention claimed is: 1. A compound of formula Number: 1 or a salt thereof 2. The compound or salt thereof according to claim 1 , wherein the compound or salt is lyophilized. 3. A composition comprising: (a) the compound and/or the salt thereof according to claim 1 ; and (b) optionally a pharmaceutically acceptable carrier. 4. The composition of claim 3 , wherein the composition further comprises an excipient. 5. The composition of claim 3 , wherein the composition is a buffered solution. 6. The composition of claim 3 , wherein the compound and/or a salt thereof, and optionally the pharmaceutical acceptable carrier, are lyophilized. 7. A compound of formula number: 1a or a salt thereof 8. The compound or salt thereof according to claim 7 , wherein the compound or salt is lyophilized. 9. A composition comprising: (c) the compound and/or the salt thereof according to claim 7 ; and (d) optionally a pharmaceutically acceptable carrier. 10. The composition of claim 9 , wherein the composition further comprises an excipient. 11. The composition of claim 9 , wherein the composition is a buffered solution. 12. The composition of claim 9 , wherein the compound and/or a salt thereof, and optionally the pharmaceutical acceptable carrier, are lyophilized.

Assignees

Inventors

Classifications

  • of the prostate · CPC title

  • Isotopically modified compounds, e.g. labelled · CPC title

  • Antineoplastic agents · CPC title

  • Medicinal preparations containing peptides (peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00) · CPC title

  • Linear peptides containing at least one abnormal peptide link · CPC title

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Frequently asked questions

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What does patent US12054458B2 cover?
The present invention generally relates to the field of radiopharmaceuticals and their use in nuclear medicine as tracers and imaging agents for various disease states of prostate cancer.
Who is the assignee on this patent?
Deutsches Krebsforsch, Univ Heidelberg Ruprecht Karls
What technology area does this patent fall under?
Primary CPC classification C07D213/61. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Aug 06 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 6 related publications on this page (citations in our corpus or others sharing the same primary CPC).