Blood gas exchanger with restriction element or elements to reduce gas exchange

Patent metadata

Field	Value
Publication number	US-12053565-B2
Application number	US-202016875889-A
Country	US
Kind code	B2
Filing date	May 15, 2020
Priority date	May 12, 2015
Publication date	Aug 6, 2024
Grant date	Aug 6, 2024

Abstract

Described is a gas exchanger with a restriction element or elements to reduce gas exchange as desired to avoid hypo-capnia and hyper-oxygenation in small patients. The gas exchanger includes a gas exchanger housing with an outer wall and a core which defines an inner wall and having a blood inlet for receiving a blood supply and a blood outlet. The gas exchanger also includes: a hollow fiber bundle disposed within the housing between the core and the outer wall; and a gas inlet compartment for receiving an oxygen supply and directing the oxygen supply to first ends of the hollow fiber bundle, wherein the gas inlet compartment includes at least one restriction element configured to allow the oxygen supply to reach only a portion of the hollow fiber bundle.

First claim

What is claimed is:

1. A gas exchanger comprising:
a gas exchanger housing including an outer wall and having a blood inlet for receiving a blood supply and a blood outlet;
a hollow fiber bundle disposed within the housing and comprising hollow gas permeable fibers, each hollow gas permeable fiber having first and second ends and a hollow interior; and
a gas inlet compartment for receiving a gas supply including oxygen and directing the gas supply to the first ends of the hollow gas permeable fibers;
wherein the gas inlet compartment includes a gas inlet configured to receive the gas supply; and
at least one restriction element, the at least one restriction element configured to allow the gas supply to reach and flow through only a portion of the hollow gas permeable fibers.

2. The gas exchanger of claim 1 , wherein the at least one restriction element is moveable between a first position and a second position.

3. The gas exchanger of claim 2 , wherein the gas supply is permitted to reach a first quantity of the hollow gas permeable fibers in the first position, and the gas supply is permitted to reach a second quantity of the hollow gas permeable fibers in the second position, the first quantity being different from the second quantity.

4. The gas exchanger of claim 1 , wherein the at least one restriction element surrounds the gas inlet.

5. The gas exchanger of claim 4 , wherein the at least one restriction element includes a gasket.

6. The gas exchanger of claim 1 , wherein the housing further comprises a purge port configured to purge air bubble from an interior of the housing.

7. The gas exchanger of claim 6 , wherein the purge port includes a threaded cap.

8. The gas exchanger of claim 6 , wherein the purge port includes a valve.

9. A gas exchanger comprising:
a gas exchanger housing including a blood inlet for receiving a blood supply and a blood outlet;
a hollow fiber bundle disposed within the housing, the hollow fiber bundle including a plurality of hollow gas permeable fibers, each hollow gas permeable fiber having a first end, a second end, and a lumen extending therethrough;
a gas inlet compartment for receiving a gas supply including oxygen; and
a restriction element located in the gas inlet compartment, wherein the restriction element is moveable from a first position to a second position, wherein when in the first position, the restriction element allows the gas supply to flow through the lumens of a first portion of the hollow gas permeable fibers and a second portion of the hollow gas permeable fibers, and when in the second position, the restriction element allows the gas supply to flow through the lumens of all the first portion of the hollow gas permeable fibers while preventing the gas supply from flowing through lumens of the second portion of the hollow gas permeable fibers.

10. The gas exchanger of claim 9 , wherein the restriction element is moveable only within the gas inlet compartment between the first position and the second position.

11. The gas exchanger of claim 10 , wherein the gas supply is permitted to reach a first quantity of the hollow gas permeable fibers in the first position, and the gas supply is permitted to reach a second quantity of the hollow gas permeable fibers in the second position, the first quantity being different from the second quantity.

12. The gas exchanger of claim 9 , wherein the restriction element surrounds the gas inlet.

13. The gas exchanger of claim 12 , wherein the restriction element includes a gasket.

14. The gas exchanger of claim 9 , wherein the blood supply is configured to flow past the first portion of the hollow gas permeable fibers including the gas supply, and the blood supply is configured to flow past the second portion of the hollow gas permeable fibers.

15. A gas exchanger comprising:
a gas exchanger housing including a blood inlet for receiving a blood supply and a blood outlet;
a hollow fiber bundle disposed within the housing, the hollow fiber bundle including a plurality of hollow gas permeable fibers, each hollow gas permeable fiber having a first end, a second end, and a lumen extending therethrough, the first ends of the hollow gas permeable fibers arranged at a first end of the hollow fiber bundle and the second ends of the hollow gas permeable fibers arranged at a second end of the hollow fiber bundle; and
a gas inlet compartment for receiving a gas supply including oxygen;
wherein the gas supply is configured to flow into the lumens of a first portion of the hollow gas permeable fibers at the first end of the hollow fiber bundle while the gas supply is prevented from flowing into the lumens of a second portion of the hollow gas permeable fibers at the first end of the hollow fiber bundle;
wherein the blood supply is configured to flow through the hollow fiber bundle to oxygenate the blood supply.

16. The gas exchanger of claim 15 , wherein the gas exchanger housing is configured to direct the blood supply from the blood inlet, past the first portion of the hollow gas permeable fibers including the gas supply, and past the second portion of the hollow gas permeable fibers to the blood outlet.

17. The gas exchanger of claim 15 , wherein the housing further comprises a purge port configured to purge air bubble from an interior of the housing.

18. The gas exchanger of claim 17 , wherein the purge port includes a threaded cap.

19. The gas exchanger of claim 17 , wherein the purge port includes a valve.

20. The gas exchanger of claim 15 , further comprising potting at the first end of the hollow fiber bundle and potting at the second end of the hollow fiber bundle, wherein the first ends of both the first and second portions of hollow gas permeable fibers are embedded in the potting at the first end of the hollow fiber bundle, and the second ends of both the first and second portions of hollow gas permeable fibers are embedded in the potting at the second end of the hollow fiber bundle.

Assignees

• Sorin Group Italia Srl

Inventors

• Mazzoli Adriano
• Reggiani Stefano

Classifications

• B01D63/034

  Lumen open in more than two directions · CPC title

• B01D63/031

  Two or more types of hollow fibres within one bundle or within one potting or tube-sheet · CPC title

• A61M1/3623

  Means for actively controlling temperature of blood · CPC title

• B01D2313/19

  Specific flow restrictors · CPC title

• B01D2313/08

  Flow guidance means within the module or the apparatus · CPC title