Production method of 226Ra target, production method of 225Ac, and electrodeposition solution for producing 226Ra target

Patent metadata

Field	Value
Publication number	US-12046385-B2
Application number	US-202017619275-A
Country	US
Kind code	B2
Filing date	Jun 18, 2020
Priority date	Jun 19, 2019
Publication date	Jul 23, 2024
Grant date	Jul 23, 2024

Abstract

One embodiment of the present invention relates to a production method of a 226Ra target, a production method of 225Ac, or an electrodeposition solution for producing a 226Ra target, and the production method of a 226Ra target includes an electrodeposition step of electrodepositing a 226Ra-containing substance on a substrate by using an electrodeposition solution that contains 226Ra ions and a pH buffer.

First claim

The invention claimed is:

1. A production method of a 226 Ra target, comprising an electrodeposition step of electrodepositing a 226 Ra-containing substance on a substrate by using an electrodeposition solution that contains 226 Ra ions and a pH buffer and that is substantially free of alcohols, wherein a value of an ON current is 0.1 to 0.3 A, and a value of an OFF current is 0.0 to 0.2 A in the electrodeposition step.

2. The production method according to claim 1 , wherein an ON time is 10 to 90 msec, and an OFF time is 10 to 90 msec in the electrodeposition step.

3. The production method according to claim 1 , wherein the electrodeposition solution further comprises carboxylate ions.

4. The production method according to claim 3 , wherein an ON time is 10 to 90 msec, and an OFF time is 10 to 90 msec in the electrodeposition step.

5. The production method according to claim 1 , wherein the electrodeposition solution further comprises one acid or two or more acids, and the acids are monovalent or divalent acids.

6. The production method according to claim 1 , wherein the electrodeposition solution is acidic at the start of the electrodeposition step.

7. The production method according to claim 1 , wherein the electrodeposition solution has a pH of 4 to 9 during the electrodeposition step.

8. The production method according to claim 1 , wherein the pH buffer is a monocarboxylate or dicarboxylate salt.

9. The production method according to claim 1 , wherein an alcohol or acetone content in the electrodeposition solution is 0.01 mass % or less.

10. The production method according to claim 1 , further comprising a purification step of purifying a 226 Ra salt-containing solution to concentrate 266 Ra ions and reduce impurities in the 226 Ra salt-containing solution,
wherein the electrodeposition step includes electrodepositing the 226 Ra-containing substance on the substrate by using the electrodeposition solution that contains 226 Ra ions obtained by the purification step.

11. The production method according to claim 10 , wherein the purification step includes an adsorption step of bringing the 226 Ra salt-containing solution into contact with a carrier having a function of selectively adsorbing divalent cations under an alkaline condition so as to cause 226 Ra ions to adsorb onto the carrier, and an elution step of causing the 226 Ra ions to elute from the carrier under an acidic condition.

12. The production method according to claim 11 , further comprising a step of an anion exchange step of passing a 226 Ra ion-containing solution eluted in the elution step through an anion exchange resin.

13. A production method of 225 Ac, comprising a step of producing a 226 Ra target by performing the production method of the 226 Ra target according to claim 1 and, an irradiating step of irradiating the 226 Ra target produced by the production method of the 226 Ra target with at least one selected from charged a particle, a photon, and a neutron.

Assignees

• Nihon Mediphysics Co Ltd

Inventors

• Kajishiro Ikuo
• Yano Shinya
• Ichinose Jun

Classifications

• G21G1/04

  outside nuclear reactors or particle accelerators · CPC title

• C25D3/54 Primary

  of metals not provided for in groups C25D3/04 - C25D3/50 · CPC title

• G21G2001/0089

  Actinium · CPC title

• G21G1/12

  by electromagnetic irradiation, e.g. with gamma or X-rays (applications of radiation G21H5/00; irradiation devices G21K5/00) · CPC title

• G21G1/10 Primary

  by bombardment with electrically charged particles (irradiation devices G21K5/00) · CPC title