Apparatus and process for producing a filter element

Patent metadata

Field	Value
Publication number	US-12042767-B2
Application number	US-202017788066-A
Country	US
Kind code	B2
Filing date	Dec 29, 2020
Priority date	Dec 31, 2019
Publication date	Jul 23, 2024
Grant date	Jul 23, 2024

Abstract

The present disclosure relates to an apparatus used in the production of a sterilizing filter for dead-end filtration of medical liquids which comprises a plurality of microporous hollow fiber membranes having a large inner diameter, and to a process for operating the apparatus.

First claim

The invention claimed is:

1. An apparatus for producing a filter element, comprising a picker arm having a plurality of grooves, wherein each groove is configured to hold a hollow fiber membrane having an outer diameter which is larger than 3 mm and smaller than 4.5 mm, and being in fluid connection with a suction device;
wherein the picker arm being mounted on a moveable block and being rotatable around its longitudinal axis (C), around a horizontal axis (A) of the moveable block which is perpendicular to the longitudinal axis (C) of the picker arm, and moved in a vertical direction (Z) with the moveable block;
a slide moveable in a horizontal direction (X) and being configured to receive a fiber cartridge holding a plurality of hollow fiber membranes having an outer diameter which is larger than 3 mm and smaller than 4.5 mm arranged in parallel and oriented in a direction perpendicular to the horizontal direction (X);
at least one heated metal pin having a conical shape, the maximum diameter of the heated metal pin being larger than an inner diameter of the hollow fiber membranes, the least one heated metal pin moveable in a vertical direction (Z 1 ) and, optionally, in a horizontal direction (XI).

2. The apparatus of claim 1 , comprising two sets of heated metal pins having a conical shape, the maximum diameter of the heated metal pins being larger than the inner diameter of the hollow fiber membranes, each of the sets comprising at least one heated metal pin.

3. The apparatus of claim 2 , wherein each of the two sets of heated metal pins is moveable in a vertical direction (Z 1 ) and in a horizontal direction (XI).

4. The apparatus of claim 1 , wherein the number of grooves on the picker arm is in the range of from 5 to 8.

5. The apparatus of claim 1 , wherein each groove of the picker arm features an elongated depression.

6. The apparatus of claim 1 , wherein each groove of the picker arm features a plurality of small bores in fluid connection with the suction device.

7. The apparatus of claim 1 , wherein the slide is configured to receive a fiber cartridge holding a number of hollow fiber membranes which is in the range of from 5 to 8.

8. The apparatus of claim 1 , wherein bolts are present on the moveable slide which are configured to interact with the fiber cartridge and ensure a defined position of the fiber cartridge on the moveable slide.

9. The apparatus of claim 1 , wherein the at least one heated metal pin is covered with a non-stick coating.

10. The apparatus of claim 1 , wherein the number of heated metal pins is equal to the number of grooves on the picker arm.

11. A process for the production of a filter element, comprising mounting a fiber cartridge comprising a plurality of hollow fiber membranes having an outer diameter which is larger than 3 mm and smaller than 4.5 mm on the moveable slide of the apparatus of claim 1 , attaching the hollow fiber membranes from the fiber cartridge to the grooves of the picker arm of the apparatus of claim 1 , threading the hollow fiber membranes through bores of a disc comprised of a thermoplastic material, introducing at least one heated metal pin of the apparatus of claim 1 into ends of the hollow fiber membranes protruding from the disc, widening the ends of the hollow fiber membranes and subsequently pushing the ends of the hollow fiber membranes into the bores of the disc and welding them to the wall of the bores of the disc.

12. The process of claim 11 , wherein different heated metal pins are used for widening the ends of the hollow fiber membranes and for pushing the ends of the hollow fiber membranes into the bores of the disc and welding them to the wall of the bores of the disc.

13. The process of claim 11 , wherein a single heated metal pin is used in sequence for widening the end of every hollow fiber membrane and for pushing the end of the hollow fiber membrane into the corresponding bore of the disc and welding it to the wall of the bore of the disc.

14. The process of claim 11 , wherein the hollow fiber membranes comprise at least one polyethersulfone (PESU) and at least one polyvinyl pyrrolidone (PVP).

15. The process of claim 11 , wherein the hollow fiber membranes additionally comprise a polymer bearing cationic charges.

Assignees

• Gambro Lundia Ab

Inventors

• Beck Christof
• Blickle Rainer
• Ermantraut Stefan
• Hertzler Bernd
• Wagner Steffen

Classifications

• B29L2031/14

  Filters {(optical filters B29L2011/0066, sieves or screens B29L2031/737)} · CPC title

• B29C65/7876

  oscillating around an axis (B29C65/7888 takes precedence) · CPC title

• B29C65/7847

  using vacuum to hold at least one of the parts to be joined (vacuum work holders in general B25B11/005) · CPC title

• B29C65/18

  using heated tools · CPC title

• B01D2323/42

  Details of membrane preparation apparatus · CPC title