Methods, devices and systems for distinguishing over-sensed R-R intervals from true R-R intervals

Patent metadata

Field	Value
Publication number	US-12042292-B2
Application number	US-202218146870-A
Country	US
Kind code	B2
Filing date	Dec 27, 2022
Priority date	Jan 30, 2020
Publication date	Jul 23, 2024
Grant date	Jul 23, 2024

Abstract

Described herein are methods, devices, and systems that monitor heart rate and/or for arrhythmic episodes based on sensed intervals that can include true R-R intervals as well as over-sensed R-R intervals. True R-R intervals are initially identified from an ordered list of the sensed intervals by comparing individual sensed intervals to a sum of an immediately preceding two intervals, and/or an immediately following two intervals. True R-R intervals are also identified by comparing sensed intervals to a mean or median of durations of sensed intervals already identified as true R-R intervals. Individual intervals in a remaining ordered list of sensed intervals (from which true R-R intervals have been removed) are classified as either a short interval or a long interval, and over-sensed R-R intervals are identified based on the results thereof. Such embodiments can be used, e.g., to reduce the reporting of and/or inappropriate responses to false positive tachycardia detections.

First claim

What is claimed is:

1. A method performed by at least one of a processor or controller of a device or system, the method comprising:
obtaining a list of sensed intervals associated with an arrhythmic episode detection;
identifying one or more true R-R intervals within the list of sensed intervals;
removing the one or more true R-R intervals, from the list of sensed intervals, to thereby produce a remaining list of sensed intervals;
classifying some individual intervals, in the remaining list of sensed intervals, as a short interval to thereby produce a list of short intervals;
using multiple discrimination criteria to classify one or more intervals in the list of short intervals as over-sensed R-R intervals; and
determining whether the arrhythmic episode detection was a false positive detection, based on results of the using the multiple discrimination criteria to classify one or more intervals in the list of short intervals as over-sensed R-R intervals.

2. The method of claim 1 , wherein each sensed interval in the list of sensed intervals has a corresponding duration, and wherein the identifying the one or more true R-R intervals within the list of sensed intervals comprises:
identifying as a said true R-R interval, each said sensed interval whose said corresponding duration is within a first specified threshold of a sum of the durations of an immediately preceding or following two intervals in the list of sensed intervals.

3. The method of claim 2 , wherein the identifying the one or more true R-R intervals within the list of sensed intervals further comprises:
identifying as a said true R-R interval, each said sensed interval whose said duration is within a second specified threshold of a mean or median of the durations of the sensed intervals already identified as true R-R intervals, wherein the second specified threshold may or may not equal the first specified threshold.

4. The method of claim 1 , wherein the multiple discrimination criteria, used to classify one or more intervals in the list of short intervals as over-sensed R-R intervals, include:
a short interval variability criterion;
a short-long interval discrepancy criterion; and
a short interval duration criterion;
wherein a said sensed interval classified as a said short interval is classified as a said over-sensed R-R interval in response to all of the short interval variability criterion, the short-long interval discrepancy criterion, and the short interval duration criterion being satisfied.

5. The method of claim 4 , wherein for a said sensed interval classified as a said short interval:
the short interval variability criterion is satisfied when a difference between the corresponding duration of the sensed interval and the corresponding duration of an immediately preceding sensed interval classified as a said short interval is within a specified threshold;
the short-long interval discrepancy criterion is satisfied when a difference between the corresponding duration of the sensed interval and the corresponding duration of an immediately following sensed interval classified as a said long interval is greater than a further specified threshold; and
the short interval duration criterion is satisfied when the corresponding duration of the sensed interval is less than another specified threshold.

6. The method of claim 1 , further comprising:
classifying other individual intervals, in the remaining list of sensed intervals, as a long interval;
classifying one or more intervals that had been classified as a said long interval as over-sensed R-R intervals, in response to an immediately preceding or following sensed interval classified as a said short interval having been identified as an over-sensed R-R interval; and
wherein the determining whether the arrhythmic episode detection was a false positive detection, is also based on results of the classifying one or more intervals that had been classified as a said long interval as over-sensed R-R intervals.

7. The method of claim 1 , wherein the determining whether the arrhythmic episode detection was a false positive detection comprises:
determining an oversensing score based on how many of the sensed intervals are classified as over-sensed R-R intervals; and
determining, based on the oversensing score, whether the arrhythmic episode detection was a false positive detection.

8. The method of claim 1 , wherein the determining whether the arrhythmic episode detection was a false positive detection comprises:
determining what percentage of the sensed intervals in the list of short intervals were classified as the over-sensed R-R intervals; and
determining the arrhythmic episode detection was a false positive detection in response to the determined percentage exceeding a specified percentage threshold.

9. The method of claim 1 , wherein the method is performed by an implantable medical device (IMD) in response to the arrhythmic episode detection being detected by the IMD.

10. The method of claim 9 , wherein the IMD is configured to transmit, to an external device that is communicatively coupled to a patient care network, data corresponding to the arrhythmic episode that is detected by the IMD, and wherein the method further comprises:
the IMD preventing or limiting transmitting, to the external device that is communicatively coupled to the patient care network, of data corresponding to the arrhythmic episode that is detected by the IMD and is thereafter determined by the IMD as being a false positive detection.

11. The method of claim 9 , wherein the obtaining the list of sensed intervals comprises:
obtaining an electrogram (EGM) segment associated with the arrhythmic episode detection;
identifying potential R-waves within the EGM segment; and
determining intervals between consecutive ones of the potential R-waves to thereby produce the list of sensed intervals.

12. The method of claim 9 , wherein the IMD comprises one of the following:
an insertable cardiac monitor (ICM);
a cardiac pacemaker to which one or more leads are attached;
a leadless cardiac pacemaker (LCP); or
an implantable cardioverter defibrillator (ICD).

13. The method of claim 9 , wherein the IMD is configured to selectively deliver therapy, and the method further comprises:
inhibiting delivery of the therapy in response to determining the arrhythmic episode detection was a false positive detection.

14. The method of claim 13 , wherein the therapy that the IMD is configured to selectively deliver, and the delivery of which is inhibited in response to determining the arrhythmic episode detection was a false positive detection, comprises at least one of anti-tachycardia pacing (ATP) or a defibrillation shock.

15. The method of claim 9 , wherein the IMD is configured to selectively deliver therapy, and the method further comprises:
causing delivery of the therapy in response to determining the arrhythmic episode detection was not a false positive detection.

16. The method of claim 15 , wherein the therapy that the IMD is configured to selectively deliver, and the delivery of which is caused in response to the arrhythmic episode detection not being determined to be a false positive detection, comprises at least one of anti-tachycardia pacing (ATP) or a defibrillation shock.

17. A device, comprising:
one or more electrodes;
a sensing circuitry coupled to the one or more electrodes and configured to obtain a signal indicative of electrical activity of a patient's heart; and
at least one of a processor or controller configured to:
detect an arrhythmic episode

Assignees

• Pacesetter Inc

Inventors

• Badie Nima
• Qu Fujian
• Gill Jong

Classifications

• A61B5/686

  Permanently implanted devices, e.g. pacemakers, other stimulators, biochips (A61B5/6861 takes precedence) · CPC title

• A61B5/0245

  by using sensing means generating electric signals, {i.e. ECG signals} · CPC title

• A61N1/3925

  Monitoring; Protecting · CPC title

• A61N1/3621

  for treating or preventing abnormally high heart rate · CPC title

• A61B5/7282

  Event detection, e.g. detecting unique waveforms indicative of a medical condition (cough events A61B5/0823; seizures A61B5/4094; sleep apnoea A61B5/4818) · CPC title