Real-time monitoring of fluid flow with flow sensing element in an aneurysm and associated devices, systems, and methods

Patent metadata

Field	Value
Publication number	US-12035919-B2
Application number	US-201816100667-A
Country	US
Kind code	B2
Filing date	Aug 10, 2018
Priority date	Aug 10, 2017
Publication date	Jul 16, 2024
Grant date	Jul 16, 2024

Abstract

Embodiments of the present disclosure are configured to assess effectiveness of an endovascular aneurysm coiling procedure. A system is provided that can include a flow sensing element supported by a structure that can position and retain the sensing element within the aneurysm. A computer in communication with the sensing element can detect a measurement of fluid flow entering the aneurysm based on data obtained by the sensing element after positioning the structure and element within an aneurysm. A wire segment can pass through the elongate member and form a coil in the aneurysm as the wire segment is passed through the elongate member. The sensing element can provide fluid flow measurements from within the aneurysm after the elongate member is removed from the vasculature.

First claim

What is claimed is:

1. A system comprising:
a structure configured to pass through a vasculature;
a wire segment configured to form a coil in an aneurysm, wherein, the wire segment has a first state that does not comprise a coil when the wire segment is disposed outside of the aneurysm and a second state once a portion of the wire segment is disposed inside of the aneurysm and forms a coil in the aneurysm;
a flow sensing element supported by the structure;
a flexible elongate member detachably attached to the structure, wherein the structure comprises a detached state when positioned in the aneurysm and retains the flow sensing element within the aneurysm; and
a computer in communication with the flow sensing element, the computer configured to:
detect, at the computer and after positioning the structure within the aneurysm in the vasculature, a measurement of fluid flow entering the aneurysm based on data obtained by the flow sensing element; and
provide a visual indication to a user as to whether the fluid flow measurement is at an unacceptable fluid flow level.

2. The system of claim 1 , further comprising a first flexible elongate member having a proximal portion, a distal portion, a central longitudinal axis, and a lumen extending along the central longitudinal axis, the first flexible elongate member sized and shaped for insertion into the vasculature.

3. The system of claim 2 , wherein the flow sensing element is a radio frequency transducer (RF) transducer that detects fluid flow entering the aneurysm.

4. The system of claim 3 , wherein the RF transducer communicates wirelessly with an RF transceiver.

5. The system of claim 4 , wherein the computer is further configured to interrogate the RF transducer, via the RF transceiver, and receive data from the RF transducer, via the RF transceiver, with the data being representative of fluid flow entering the aneurysm.

6. The system of claim 4 , wherein the computer is further configured to interrogate the RF transducer, via the RF transceiver, after the first flexible elongate member is removed from the vasculature and receive data from the RF transducer, via the RF transceiver, after the first flexible elongate member is removed.

7. The system of claim 2 , wherein the wire segment is configured to pass through the lumen, wherein the wire segment forms the coil in the aneurysm as the wire segment is passed through the lumen, and wherein the aneurysm is in a wall of a vessel in the vasculature.

8. The system of claim 7 , wherein the structure is selected from a group consisting of the wire segment, a substrate, a container, and a flexible material.

9. The system of claim 8 , wherein the structure can be delivered to the aneurysm via a second flexible elongate member and deposited in the aneurysm by a detachable connector that releasably connects the structure to a distal end of the second flexible elongate member, and wherein the structure and the flow sensing element remain in the aneurysm when the first and second flexible elongate members are removed from the vasculature.

10. The system of claim 7 , wherein the computer is further configured to detect, at the computer and after forming the coil in the aneurysm, the measurement of fluid flow entering the aneurysm.

11. The system of claim 7 , wherein the wire segment includes fibrous material fixedly attached along the wire segment, and wherein the fibrous material enhances clotting in and around the coil.

12. The system of claim 7 , wherein the wire segment comprises multiple wire segments, and each one of the wire segments forms a coil when the respective wire segment passes through the lumen and into the aneurysm.

13. The system of claim 1 , wherein the computer is further configured to:
determine, at the computer, that the fluid flow measurement is at or below an acceptable fluid flow level; and
provide a visual indication to a user as to whether the fluid flow measurement is at or below the acceptable fluid flow level.

14. A method of evaluating an endovascular aneurysm coiling procedure, the method comprising:
guiding a distal portion of a first flexible elongate member through a vasculature and into an aneurysm in a vessel of the vasculature;
delivering a flow sensing element to the aneurysm by guiding the flow sensing element through a lumen that extends through the first flexible elongate member, wherein the delivering further comprises passing a second flexible elongate member through the lumen, and depositing the flow sensing element in the aneurysm by releasing a detachable connector that releasably connects a structure, on which the flow sensing element is disposed, to a distal end of the second flexible elongate member;
detecting, at a computer and after positioning a coil within the aneurysm, a first measurement of fluid flow entering the aneurysm based on data obtained by the flow sensing element disposed in the aneurysm, with the flow sensing element in communication with the computer;
determining, at the computer, that the first fluid flow measurement is at or below an acceptable fluid flow level; and
outputting, to a display in communication with the computer, a first graphical representation that the first fluid flow measurement is at or below the acceptable fluid flow level.

15. The method of claim 14 , further positioning a further coil when the first fluid flow measurement is at an unacceptable level, wherein the positioning the further coil, detecting the first fluid flow measurement, the determining, and the outputting are repeated until the first fluid flow measurement is at or below the acceptable level.

16. The method of claim 14 , further comprising passing a wire segment through a first flexible elongate member such that the wire segment exits from a distal portion of the first flexible elongate member and gathers together in the aneurysm to form the coil in the aneurysm, thereby positioning the coil within the aneurysm.

17. The method of claim 14 , wherein the structure is selected from the group consisting of a wire segment, a substrate, a container, and a flexible material.

18. The method of claim 14 , further comprising:
removing the first and second flexible elongate members from the vasculature, wherein the structure remains in the aneurysm after the removing; and
detecting, at the computer and after the removing, a second measurement of fluid flow entering the aneurysm based on data obtained by the flow sensing element.

19. A system comprising:
a catheter configured to pass through a vasculature and having a lumen through which a wire segment passes, the catheter configured to perform an endovascular aneurysm coiling procedure in which the wire segment is pushed into an aneurysm of the vasculature and forms a blood flow-blocking coil within the aneurysm;
a flow sensing element disposed on a structure such that the flow sensing element can be pushed into the aneurysm via the catheter and is disposed in proximity to the blood flow-blocking coil formed within the aneurysm in the endovascular aneurysm coiling procedure;
a flexible elongate member attachable to the structure with a detachable connector, the flexible elongate member configured for delivering the flow sensing element to the aneurysm by guiding the structure through a lumen that extends through the catheter; and
a computer in communication with the flow sensing element, the computer configured to detect, at the computer and after the flow sensing element is pushed into the aneurysm with the wire segment and after formation of

Assignees

• Koninklijke Philips Nv
• Philips Image Guided Therapy Corp

Inventors

• Unser John

Classifications

• A61B5/027

  using catheters · CPC title

• A61B8/56

  Details of data transmission or power supply · CPC title

• A61B2017/00022

  Sensing or detecting at the treatment site · CPC title

• A61B8/06

  Measuring blood flow · CPC title

• A61B8/4483

  characterised by features of the ultrasound transducer · CPC title