Bench-top Time of Flight mass spectrometer

Patent metadata

Field	Value
Publication number	US-12027359-B2
Application number	US-201917056999-A
Country	US
Kind code	B2
Filing date	May 31, 2019
Priority date	May 31, 2018
Publication date	Jul 2, 2024
Grant date	Jul 2, 2024

Abstract

A Time of Flight analyser comprising a flight tube ( 160 ) and a reflectron ( 170 ), wherein the reflectron comprises a stack of electrodes ( 172 ) that are compressed against the flight tube such that they remain parallel to each other under compression.

First claim

The invention claimed is:

1. A Time of Flight analyser comprising:
a flight tube having:
a plurality of radially extending protrusions formed around a circumference of the flight tube, wherein each of the plurality of radially extending protrusions has a respective recess formed therein;

a reflectron mounted to an end of the flight tube such that it receives ions passing through the end of the flight tube, wherein the reflectron comprises a stack of electrodes that are compressed against the end of the flight tube and each of the electrodes includes apertures;
a plurality of rods, wherein each of the rods extends through selected ones of the apertures in the electrodes and into a respective one of the recesses formed in a respective one of the plurality of radially extending protrusions, wherein each of plurality of rods includes an aperture that is exposed at the respective one of the recesses in the respective one of the plurality of radially extending protrusions and,
a plurality of pins, wherein, for each rod of the plurality of rods, a pin is inserted through the aperture of the rod that is exposed at the respective one of the recesses in the respective one of the plurality of radially extending protrusions for preventing the rod from moving in a direction away from the flight tube; and
wherein the Time of Flight analyser comprises one or more resilient members configured to bias the stack of electrodes towards the flight tube, so as to compress the stack of electrodes against the flight tube.

2. A Time of Flight analyser as claimed in claim 1 , wherein the stack of electrodes comprises a plurality of ring electrodes.

3. A Time of Flight analyser as claimed in claim 1 , wherein the stack of electrodes are compressed such that they remain parallel to each other under compression.

4. A Time of Flight analyser as claimed in claim 1 , wherein each of the one or more resilient members are biased between a respective one of the rods and the stack of electrodes to compress the stack of electrodes against the flight tube.

5. A Time of Flight analyser as claimed in claim 4 , wherein each of the one or more resilient members urges against a foot of a respective one of the rods and a portion of the reflectron.

6. A Time of Flight analyser as claimed in claim 5 , wherein the portion of the reflectron is a bottom surface or plate thereof.

7. A Time of Flight analyser as claimed in claim 4 , further comprising a plurality of electrically insulating spacers in between each of the electrodes in the stack of electrodes, wherein each spacer extends around a respective one of the one or more rods and is compressed between the electrodes by the biasing force exerted by the resilient member.

8. A Time of Flight analyser as claimed in claim 7 , wherein the spacers define the separation distance of the electrodes in the stack of electrodes.

9. A Time of Flight analyser as claimed in claim 8 , wherein the separation distance corresponds to the spacing between the electrodes in a direction parallel to a central, longitudinal axis of the reflection.

10. A Time of Flight analyser as claimed in claim 7 , wherein the spacers are all of the same size.

11. A Time of Flight analyser as claimed in claim 1 , wherein each rod is straight and the selected apertures in the electrodes are aligned so as to receive the straight rod and insertion of the straight rod through the selected apertures in the electrodes aligns the electrodes in an in use orientation.

12. A method of constructing a Time of Flight analyser as claimed in claim 1 , the method comprising the steps of:
(i) assembling a stack of electrodes to form a reflectron; and
(ii) compressing the stack of electrodes against a flight tube.

13. A Time of Flight analyser as claimed in claim 1 , wherein the one or more resilient members are one or more springs configured to urge the stack of electrodes towards the flight tube.

14. A Time of Flight analyser as claimed in claim 1 , wherein the flight tube and reflectron have a central axis that is substantially vertical.

Assignees

• Micromass Ltd

Inventors

• Carney Peter
• Chummar Soji
• Wildgoose Jason Lee
• Wamsley Ruth

Classifications

• H01J49/405

  characterised by the reflectron, e.g. curved field, electrode shapes · CPC title

• H01J49/401

  characterised by orthogonal acceleration, e.g. focusing or selecting the ions, pusher electrode · CPC title

• H01J49/065

  having stacked electrodes, e.g. ring stack, plate stack · CPC title

• H01J49/04

  Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components · CPC title

• H01J49/0031

  Step by step routines describing the use of the apparatus (H01J49/0081 takes precedence) · CPC title