Methods, compositions, and devices for supplying dietary fatty acid needs
US-12059391-B2 · Aug 13, 2024 · US
Method of treatment of obesity
US12023313B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12023313-B2 |
| Application number | US-202117156894-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 25, 2021 |
| Priority date | Mar 15, 2016 |
| Publication date | Jul 2, 2024 |
| Grant date | Jul 2, 2024 |
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- Title
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Abstract
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The present invention provides compositions and pharmaceutical compositions of GPR84 agonists and GPR120 agonists for use in the treatment of obesity and overweight. The invention provides methods of treatment accordingly as well as a kit for use in the treatment of obesity and overweight.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method of treating obesity and overweight comprising administering to a subject in need thereof a composition comprising a GPR84 agonist and a GPR120 agonist, wherein the GPR84 agonist is 3,3′-diindolylmethane and wherein the GPR120 agonist is α-linolenic acid (ALA) or an ester thereof, wherein the composition is a delayed release formulation for release in the distal small intestine and large intestine. 2. The method as claimed in claim 1 , in which the GPR120 agonist is from a natural source. 3. The method as claimed in claim 2 , in which the natural source of GPR120 agonist is a plant seed oil. 4. The method as claimed in claim 1 , wherein the composition further comprises an amino acid. 5. The method as claimed in claim 1 , wherein the composition is administered orally. 6. The method as claimed in claim 1 , wherein the delayed release formulation is a delayed release capsule. 7. The method as claimed in claim 6 , wherein the delayed release capsule comprises a polymer of methacrylic acid and methyl methacrylate. 8. The method as claimed in claim 1 , wherein the composition further comprises the GPR84 agonist lauric acid.
Assignees
Inventors
Classifications
having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid {(cannabinoids A61K31/658)} · CPC title
Linaceae (Flax family), e.g. Linum · CPC title
Anorexiants; Antiobesity agents · CPC title
- A61K31/20Primary
having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids · CPC title
- A61K31/01Primary
Hydrocarbons · CPC title
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Frequently asked questions
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- What does patent US12023313B2 cover?
- The present invention provides compositions and pharmaceutical compositions of GPR84 agonists and GPR120 agonists for use in the treatment of obesity and overweight. The invention provides methods of treatment accordingly as well as a kit for use in the treatment of obesity and overweight.
- Who is the assignee on this patent?
- Univ London Queen Mary
- What technology area does this patent fall under?
- Primary CPC classification A61K31/20. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jul 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).