Stent including anti-migration capabilities

Patent metadata

Field	Value
Publication number	US-12023265-B2
Application number	US-202016743049-A
Country	US
Kind code	B2
Filing date	Jan 15, 2020
Priority date	Jan 16, 2019
Publication date	Jul 2, 2024
Grant date	Jul 2, 2024

Abstract

An example medical device for treating a body lumen is disclosed. The medical device includes an expandable scaffold including a first end region, a second end region opposite the first end region and an outer surface. The medical device also includes a covering disposed along the outer surface of the expandable scaffold, the covering having an outer surface. The medical device further includes a plurality of granular particles disposed along the covering. Additionally, the expandable scaffold is configured to shift from a collapsed state to an expanded state, the covering is configured to contact an inner surface of the body lumen in the expanded state and the granular particles are designed to prevent migration of the expandable scaffold upon implantation in the body lumen.

First claim

What is claimed is:

1. A medical device for treating a body lumen, comprising:
an expandable scaffold including a first end region, a second end region opposite the first end region and an outer surface;
a polymeric covering disposed along the outer surface of the expandable scaffold, the covering having an outer surface, wherein the polymeric covering is not biodegradable; and
a plurality of granular particles disposed along the covering, wherein the granular particles comprise at least a first microbead having a first outer diameter, and wherein the first outer diameter is between 0.5 mm and 0.9 mm wherein adjacent ones of the plurality of granular particles are stacked radially outward from the outer surface of the expandable scaffold one on top of another;
wherein the expandable scaffold is configured to shift from a collapsed state to an expanded state;
wherein the covering is configured to contact an inner surface of the body lumen in the expanded state;
wherein the granular particles are designed to prevent migration of the expandable scaffold upon implantation in the body lumen.

2. The medical device of claim 1 , wherein at least some of the plurality of granular particles are encapsulated within the covering.

3. The medical device of claim 2 , wherein some of the granular particles are disposed along the outer surface of the covering.

4. The medical device of claim 1 , wherein the first microbead is spherically-shaped.

5. The medical device of claim 1 , further comprising a second microbead, and wherein the second microbead extends radially outward from the outer surface of the expandable scaffold a greater distance than the first microbead extends from the outer surface of the expandable scaffold.

6. The medical device of claim 1 , wherein the expandable scaffold includes a plurality of interstices located therein, and wherein the covering spans at least one of the plurality of interstices.

7. The medical device of claim 1 , wherein the plurality of granular particles are arranged to create a surface texture having a variable surface roughness.

8. The medical device of claim 1 , wherein the covering includes a first thickness and a second thickness different from the first thickness.

9. The medical device of claim 1 , wherein the first end region, the second end region or both the first end region and the second end region include a flared portion.

10. The medical device of claim 1 , wherein the covering is disposed along the entire outer surface of the expandable scaffold.

11. A medical device for treating a body lumen, comprising:
an expandable scaffold including a first end region, a second end region opposite the first end region and an outer surface;
a polymeric covering disposed along the outer surface of the expandable scaffold, wherein the polymeric covering is not biodegradable; and
a plurality of microbeads disposed along the covering, the microbeads having a first outer diameter between 0.50 mm and 0.90 mm;
wherein the plurality of microbeads are disposed along the covering to form a variable surface texture, wherein adjacent ones of the plurality of microbeads are stacked radially outward from the outer surface of the expandable scaffold one on top of another;
wherein the covering is configured to contact an inner surface of the body lumen such that the plurality of microbeads prevent migration of the expandable scaffold upon implantation in the body lumen.

12. The medical device of claim 11 , wherein the plurality of microbeads are encapsulated within the covering.

13. The medical device of claim 11 , wherein at least some of the plurality of microbeads are spherically-shaped.

14. The medical device of claim 11 , wherein the plurality of microbeads includes a first microbead and a second microbead, and wherein the second microbead extends radially outward from the outer surface of the expandable scaffold a greater distance than the first microbead extends from the outer surface of the expandable scaffold.

15. The medical device of claim 11 , wherein the covering includes a first thickness and a second thickness different from the first thickness.

16. A medical device for treating a body lumen, comprising:
an expandable scaffold including a first end region, a second end region opposite the first end region and an outer surface;
a polymeric covering disposed along the outer surface of the expandable scaffold, the covering having an outer surface, wherein the polymeric covering is not biodegradable; and
a plurality of granular particles disposed along the covering, wherein the granular particles comprise at least a first microbead having a first outer diameter, and wherein the first outer diameter is between 0.5 mm and 0.9 mm, and wherein adjacent ones of the plurality of granular particles are stacked radially outward from the outer surface of the expandable scaffold one on top of the other wherein a first portion of the granular particles are fully embedded within the covering and a second portion of the granular particles extend radially outward from the outer surface of the polymeric covering;
wherein the expandable scaffold is configured to shift from a collapsed state to an expanded state;
wherein the covering is configured to contact an inner surface of the body lumen in the expanded state;
wherein the granular particles are designed to prevent migration of the expandable scaffold upon implantation in the body lumen.

Assignees

• Boston Scient Scimed Inc

Inventors

• Gilmartin Gary
• Toner Geraldine
• Tuck Daniel

Classifications

• A61F2250/0036

  differing in thickness · CPC title

• A61F2250/0025

  differing in roughness · CPC title

• A61F2220/0008

  Fixation appliances for connecting prostheses to the body · CPC title

• A61L2400/18

  Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment · CPC title

• A61L31/10

  Macromolecular materials · CPC title