Acoustic sub-aperture processing for ultrasound imaging

Patent metadata

Field	Value
Publication number	US-12019156-B2
Application number	US-201716310181-A
Country	US
Kind code	B2
Filing date	Jun 16, 2017
Priority date	Jun 16, 2016
Publication date	Jun 25, 2024
Grant date	Jun 25, 2024

Abstract

A method for ultrasound data processing includes transmitting an ultrasound excitation signal from each element of a transducer array and receiving a response signal from each element of a transducer array. Each response signal corresponds to a respective channel. Each response signal is sampled at one or more time points in the response signal to create a plurality of samples, each sample corresponding to a channel and a time point. The samples are divided into at least two groups. Response signals from the first group are beamformed and response signals from the second group are beamformed separately. The process is repeated over multiple data frames. The beamformed signals of each group are correlated over the multiple data frames and beamformed signals having a lower degree of correlation or negative correlation are selectively attenuated. An image output is generated from the correlation output.

First claim

The invention claimed is:

1. A method for ultrasound data processing comprising:
i) transmitting ultrasound excitation signals from elements of a transducer array;
ii) receiving response signals from elements of the transducer array, each response signal corresponding to a respective channel;
iii) sampling each response signal at one or more time points in the response signal to create a plurality of samples, each sample corresponding to a channel and a time point;
iv) dividing the plurality of samples into at least two different or partially overlapping groups;
v) beamforming the response signals from the first group;
vi) beamforming the response signals from the second group;
vii) repeating steps i) to vi) for M data frames, wherein a data frame comprises sampled response signals in respect of each of a plurality of pixels of an image space for a given ultrasound transmission and where M is greater than 1;
viii) multiplying pixelwise the beamformed signals of each group and averaging the multiplication over the M data frames, resulting in improved signal-to-noise ratio and comprising:
generating, for each data frame of the M data frames, a sample output, wherein the sample output comprises an integral over the M data frames or the M data frames-temporal frequency of the beamformed response signals from the first group multiplied by the beamformed response signals from the second group for that data frame, wherein the beamformed response signals from the first or second group is conjugate transformed before integration, and
averaging the sample output for a first data frame with the sample outputs from subsequent data frames up to the M th data frame; and

ix) providing the averaged sample outputs as an image output for at least a first pixel of the plurality of pixels of the image space.

2. The method of claim 1 in which the first group comprises samples from the same time point of each of a plurality of channels and the second group comprises samples from that same time point of each of a different plurality of channels.

3. The method of claim 1 in which the first group comprises samples from a first time point of each of a plurality of channels and the second group comprises samples from a second time point of each of the same plurality of channels.

4. The method of claim 1 in which the first group comprises samples from a first time point of each of a first plurality of channels and a second time point of each of a second plurality of channels, and the second group comprises samples from the first time point of each of the second plurality of channels and the second time point of each of the first plurality of channels.

5. The method of claim 1 in which the at least two groups of samples are selected according to at least one of the following conditions:
each sample is allocated to only one group;
each group has the same number of samples;
a majority of adjacent elements in the array are allocated to different groups;
a majority of the data samples are not common in the different groups,
samples are allocated to the groups randomly or adaptively by optimizing a measure of the received data.

6. The method of claim 1 further including filtering each beamformed set of response signals to suppress clutter signal components or other unwanted components.

7. The method of claim 6 in which filtering each beamformed set of response signals comprises filtering with a high pass filter.

8. The method of claim 7 in which the high pass filter is one of a derivative estimator; a second order FIR filter and an IIR filter.

9. The method of claim 1 in which step viii) comprises attenuating the multiplied beamformed signals as a function of the phase value of the multiplied beamformed signals.

10. The method of claim 1 in which step viii) produces a final sample output and further comprises applying different filters for each group of response signals so as to include the phase of a Doppler spectrum in the final sample output, to infer blood dynamics information or using phase components of the multiplied beamformed signals to infer blood dynamics information.

11. The method of claim 10 in which the blood dynamics information comprises direction of flow.

12. The method of claim 1 further including normalizing the sample outputs with respect to the magnitude of the beamformed response signals.

13. The method of claim 6 in which step viii) comprises using different filters for each group, thereby obtaining a more complex filtering and/or include phase information in the multiplication to select different flow velocities.

14. The method of claim 13 in which the different filters are designed with a phase shift between positive and negative frequencies, in order to extract flow direction information.

15. The method of claim 1 further including displaying a magnitude of the averaged sample outputs for each of the plurality of pixels in a two dimensional array of pixels of image space, in a process of ultrasound imaging.

16. The method of claim 1 in which the process is carried out substantially in real time with the collection of response signals in respect of each of the plurality of pixels of image space and for a succession of the M data frames.

17. An ultrasound processing apparatus configured to:
i) transmit ultrasound excitation signals from elements of a transducer array;
ii) receive response signals from elements of the transducer array, each response signal corresponding to a respective channel;
iii) sample each response signal at one or more time points in the response signal to create a plurality of samples, each sample corresponding to a channel and a time point;
iv) divide the plurality of samples into at least two different or partially overlapping groups;
v) beamform the response signals from the first group;
vi) beamform the response signals from the second group;
vii) repeat steps i) to vi) for M data frames, wherein a data frame comprises sampled response signals in respect of each of a plurality of pixels of an image space fora given ultrasound transmission and where M is greater than 1;
viii) multiply pixelwise the beamformed signals of each group and average the multiplication over the M data frames, resulting in improved signal-to-noise ratio and comprising:
generating, for each data frame of the M data frames, a sample output, wherein the sample output comprises an integral over the M data frames or the M data frames-temporal frequency of the beamformed response signals from the first group multiplied by the beamformed response signals from the second group for that data frame, wherein the beamformed response signals from the first or second group is conjugate transformed before integration, and
averaging the sample output for a first data frame with the sample outputs from subsequent data frames up to the Mth data frame; and

ix) provide the averaged sample outputs as an image output for at least a first pixel of the plurality of pixels of the image space.

Assignees

• Imperial College Innovations Ltd

Inventors

• Stanziola Antonio
• Tang Mengxing

Classifications

• A61B8/06

  Measuring blood flow · CPC title

• A61B8/488

  involving Doppler signals · CPC title

• G01S7/52039

  exploiting the non-linear response of a contrast enhancer, e.g. a contrast agent (diagnostic techniques involving the use of contrast agents A61B8/481) · CPC title

• G10K11/341

  Circuits therefor · CPC title

• G01S15/8915 Primary

  using a transducer array · CPC title