Cartridge and apparatus for preparing a biological sample
US-2015316454-A1 · Nov 5, 2015 · US
US12019094B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12019094-B2 |
| Application number | US-201716603013-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 21, 2017 |
| Priority date | Apr 6, 2017 |
| Publication date | Jun 25, 2024 |
| Grant date | Jun 25, 2024 |
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Provided is a device for measuring a microfluid flow velocity, having a structure separable by an ultra-thin film, the device including a first panel including a flow velocity measurement structure configured to measure a flow velocity of a fluid, a second panel configured to be separated from the first panel and including a microfluid channel through which a sample passes, and the ultra-thin film formed in a portion where the first panel and the second panel adjoin each other, the ultra-thin film being configured to separate the first panel and the second panel so that the sample passing through the microfluid channel does not come into direct contact with the flow velocity measurement structure, in which the first panel including the flow velocity measurement structure is usable multiple times repeatedly.
Opening claim text (preview).
The invention claimed is: 1. A device for measuring a microfluid flow velocity, the device comprising: a first panel comprising a flow velocity measurement structure configured to measure a flow velocity of a fluid; a second panel configured to be separated from the first panel and comprising a microfluid channel through which a sample passes, a vacuum groove being formed in a lower surface of the second panel, and a vacuum suction portion being formed in a lateral surface of the first panel or the second panel to communicate with the vacuum groove; and an ultra-thin film detachably placed, without being coated onto the first panel or the second panel, in a portion between the vacuum groove and the vacuum suction portion where the first panel and the second panel adjoin each other, the ultra-thin film being configured to separate the first panel and the second panel so that the sample passing through the microfluid channel does not come into direct contact with the flow velocity measurement structure, wherein the first panel comprising the flow velocity measurement structure is usable multiple times repeatedly, and wherein a material of the ultra-thin film comprises one or more materials selected from polydimethyl siloxane (PDMS) and polyimide (PI). 2. The device of claim 1 , wherein the flow velocity measurement structure comprises: a heater configured to apply heat to the sample passing through the microfluid channel; and two temperature measuring electrodes installed at front and rear sides of the heater to measure a resistance difference in accordance with a change in temperature of the sample when the temperature of the sample is increased by the heat generated by the heater. 3. The device of claim 1 , further comprising: a vacuum attachment means configured to apply a vacuum to hold the first panel and the second panel by the vacuum. 4. The device of claim 3 , wherein the vacuum attachment means comprises: a vacuum suction portion configured to communicate with the vacuum groove to apply the vacuum and hold, by the vacuum, the first panel and the second panel so that an air layer between the first panel and the second panel is completely removed. 5. The device of claim 4 , wherein the vacuum groove is shaped and positioned to surround the microfluid channel. 6. The device of claim 1 , wherein the microfluid channel comprises: a fluid injection port configured to inject the sample; a fluid channel through which the sample introduced into the fluid injection port flows; and a fluid discharge port from which the sample flowing through the fluid channel is discharged. 7. The device of claim 1 , wherein the first panel and the second panel are separable, and the second panel comprising the microfluid channel through which the sample passes is replaced and used in accordance with a measuring range of a fluid flow velocity intended to be measured by a user, such that the first panel is usable universally without limiting a measurable range of the flow velocity. 8. The device of claim 1 , wherein the material of the ultra-thin film comprises polydimethyl siloxane (PDMS). 9. The device of claim 1 , wherein the material of the ultra-thin film comprises polyimide (PI). 10. The device of claim 1 , wherein the material of the ultra-thin film comprises polydimethyl siloxane (PDMS) and polyimide (PI).
Sensor or part of a sensor is integrated · CPC title
Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks · CPC title
Means for pressure control · CPC title
Specific details about materials · CPC title
Whole sensors · CPC title
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