Single insertion delivery system for treating embolism and associated systems and methods

Patent metadata

Field	Value
Publication number	US-12016580-B2
Application number	US-202117498642-A
Country	US
Kind code	B2
Filing date	Oct 11, 2021
Priority date	Jan 26, 2018
Publication date	Jun 25, 2024
Grant date	Jun 25, 2024

Abstract

Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, engaging an interventional device of a catheter system with clot material in a blood vessel and withdrawing the interventional device and the portion of the clot material through a guide catheter. In some embodiments, the catheter system can include an attachment/valve member coupled to a proximal portion of the guide catheter, and the method can include unsealing the attachment/valve member to facilitate withdrawing the interventional device through the attachment/valve member without significant retention of clot material within the attachment/valve member. The method can further include resealing and aspirating the guide catheter before advancing another interventional device to the clot material to again engage and remove clot material from the blood vessel.

First claim

We claim:

1. A method for the intravascular treatment of clot material within a blood vessel, the method comprising:
positioning a distal portion of an elongated shaft proximate to the clot material within the blood vessel;
pre-charging a vacuum in a pressure source;
fluidly connecting the pressure source to the elongated shaft to apply the pre-charged vacuum to the elongated shaft to aspirate a first portion of the clot material into the elongated shaft;
unsealing an attachment member coupled to a proximal portion of the elongated shaft;
advancing an interventional device distally through the attachment member and the elongated shaft; and
engaging the interventional device with a second portion of the clot material remaining within the blood vessel.

2. The method of claim 1 wherein the method further comprises withdrawing the interventional device and the second portion of the clot material into the elongated shaft.

3. The method of claim 2 wherein the method further comprises withdrawing the interventional device and the second portion of the clot material through the attachment member.

4. The method of claim 3 wherein the method further comprises unsealing the attachment member before withdrawing the interventional device and the second portion of the clot material through the attachment member.

5. The method of claim 1 wherein unsealing the attachment member includes exercising a valve of the attachment member such that a lumen of the attachment member has a diameter that is about equal to an inner diameter of the elongated shaft.

6. The method of claim 1 wherein unsealing the attachment member includes pressing one or more buttons on the attachment member.

7. The method of claim 1 wherein the pressure source is a syringe.

8. The method of claim 7 wherein pre-charging the vacuum includes withdrawing a plunger of the syringe.

9. The method of claim 1 wherein fluidly connecting the pressure source to the elongated shaft to apply the pre-charged vacuum generates suction at the distal portion of the elongated shaft.

10. The method of claim 1 wherein the blood vessel is a pulmonary blood vessel.

11. The method of claim 1 wherein the pressure source is fluidly coupled to the elongated shaft via a fluid control device, and wherein (a) opening of the fluid control device fluidly connects the pressure source to the elongated shaft and (b) closing of the fluid control device fluidly disconnects the pressure source from the elongated shaft.

12. The method of claim 11 wherein pre-charging the vacuum in the pressure source includes activating the pressure source while the fluid control device is closed, and wherein fluidly connecting the pressure source to the elongated shaft includes opening the fluid control device.

13. The method of claim 11 wherein the fluid control device comprises a user-actuatable valve.

14. The method of claim 1 wherein the attachment member comprises a hemostasis valve.

15. The method of claim 14 wherein the hemostasis valve includes a tubular member, a button, and a filament coupled to the button and the tubular member, and wherein unsealing the hemostasis valve includes pressing the button to loosen the filament to allow the tubular member to expand.

16. The method of claim 15 wherein the method further comprises, after at least partially advancing the interventional device distally through the hemostasis valve, releasing the button to tighten the filament to allow the tubular member to collapse and seal about a portion of the interventional device.

17. The method of claim 16 wherein the hemostasis valve further includes a spring, and wherein releasing the button to tighten the filament includes driving the button with the spring to tighten the filament.

18. The method of claim 1 wherein the method further comprises collecting at least some of the first portion of the clot material within a filter chamber fluidly coupled between the pressure source and the elongated shaft.

19. The method of claim 18 wherein the method further comprises removing a filter from within the filter chamber to provide access to the at least some of the first portion of the clot material.

20. The method of claim 19 wherein the filter includes a plurality of pores sized to inhibit the clot material from flowing therethrough and to permit blood to flow therethrough.

21. The method of claim 18 wherein the filter chamber is fluidly coupled to the elongated shaft via a first fluid path, wherein the attachment member is fluidly coupled to the elongated shaft along a second fluid path, and wherein the first fluid path branches from the second fluid path.

22. The method of claim 21 wherein the attachment member is a hemostasis valve.

23. The method of claim 22 wherein unsealing the hemostasis valve includes actuating at least one button of the hemostasis valve.

24. The method of claim 18 wherein the filter chamber is spaced apart from the pressure source and connected to the pressure source via at least one tube.

25. The method of claim 18 wherein the filter chamber comprises a housing and a filter within the housing, and wherein the housing includes—
a port configured to be fluidly coupled to the elongated shaft via at least one first tube; and
a fluid connector configured to be coupled to the pressure source via at least one second tube, wherein the filter is in the housing and fluidly coupled between the port and the fluid connector, and wherein the elongated shaft is fluidly coupled to the pressure source via the filter chamber.

26. The method of claim 25 wherein the elongated shaft is fluidly coupled to the pressure source via the filter chamber along a first fluid path.

27. The method of claim 26 wherein the attachment member is fluidly coupled to the elongated shaft along a second fluid path at least partially different than the first fluid path.

28. The method of claim 27 wherein the attachment member comprises a hemostasis valve.

29. The method of claim 28 wherein unsealing the hemostasis valve includes actuating at least one button of the hemostasis valve.

30. The method of claim 1 wherein engaging the interventional device with the second portion of the clot material remaining within the blood vessel includes translating the interventional device relative to the elongated shaft.

31. The method of claim 1 wherein the method further comprises flushing the clot container with a fluid after aspirating the first portion of the clot material into the elongated shaft and/or after engaging the interventional device with the second portion of the clot material.

32. The method of claim 31 wherein the fluid is saline.

33. The method of claim 1 wherein the pressure source is coupled to the elongated shaft via at least one tube, and wherein the method further comprises flushing the at least one tube with a fluid after aspirating the first portion of the clot material into the elongated shaft and/or after engaging the interventional device with the second portion of the clot material.

34. The method of claim 33 wherein the fluid is saline.

Assignees

• Inari Medical Inc

Inventors

• Quick Richard
• Merritt Benjamin Edward
• Thress John Coleman
• Lubock Paul
• Tu Thomas M

Classifications

• A61B17/221

  Gripping devices in the form of loops or baskets {for gripping calculi or similar types of obstructions (surgical snare instruments A61B17/32056)} · CPC title

• A61M39/06

  Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof · CPC title

• A61B2217/005

  with suction drainage system · CPC title

• A61B2017/00907

  for light · CPC title

• A61B17/22 Primary

  Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for · CPC title