Inhalable Antimicrobial Particles and Methods of Making the Same
US-2020179287-A1 · Jun 11, 2020 · US
Microgel composition comprising collagen and method of preparing the same
US12005152B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-12005152-B2 |
| Application number | US-202117168780-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 5, 2021 |
| Priority date | Feb 7, 2020 |
| Publication date | Jun 11, 2024 |
| Grant date | Jun 11, 2024 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
The present disclosure relates to a microgel composition comprising collagen and hyaluronic acid and a method of preparing the same. The microgel according to an embodiment is composed of natural biocompatible substances and is non-toxic and has high mechanical stability or long persistence, and thus can be effectively used in a microgel composition, a three-dimensional scaffold composition, and a tissue-engineering scaffold.
First claim
Opening claim text (preview).
What is claimed is: 1. A microgel composition comprising 10% (w/v) of collagen and 2.5% (w/v) to 5% (w/v) of hyaluronic acid, wherein the composition has a zeta potential of −50 mV to −30 mV, wherein the composition has a pH of 4 to 11, and wherein the microgel is in the form of a nonwoven fabric; a woven fabric; a knitted fabric; a fiber bundle; a cylinder including a fiber bundle and a tube into which the fiber bundle is inserted; or a combination of two or more thereof. 2. The microgel composition of claim 1 , wherein the microgel has a size of 10 μm to 250 μm. 3. The microgel composition of claim 1 , wherein the composition is a cell-laden microgel. 4. The microgel composition of claim 1 , wherein the composition does not comprise a chemical crosslinking agent. 5. A three-dimensional scaffold comprising 10% (w/v) of collagen and 2.5% (w/v) to 5% (w/v) of hyaluronic acid, wherein the scaffold has a zeta potential of −50 mV to −30 mV, and wherein the scaffold is in the form of a nonwoven fabric; a woven fabric; a knitted fabric; a fiber bundle; a cylinder including a fiber bundle and a tube into which the fiber bundle is inserted; or a combination of two or more thereof. 6. A scaffold for tissue engineering, comprising 10% (w/v) of collagen and 2.5% (w/v) to 5% (w/v) of hyaluronic acid, wherein the scaffold has a zeta potential of −50 mV to −30 mV, and wherein the scaffold is in the form of a nonwoven fabric; a woven fabric; a knitted fabric; a fiber bundle; a cylinder including a fiber bundle and a tube into which the fiber bundle is inserted; or a combination of two or more thereof. 7. A method of preparing a microgel composition, the method comprising: forming an electrostatic collagen-hyaluronic acid complex by reacting 10% (w/v) of collagen and 2.5% (w/v) to 5% (w/v) of hyaluronic acid; preparing a dispersion of a microgel by breaking the collagen-hyaluronic acid complex; and adjusting pH level of the dispersion to 4-11, subjecting the dispersion of the microgel to natural sedimentation, wherein the composition has a zeta potential of −50 mV to −30 mV, and wherein the microgel is in the form of a nonwoven fabric; a woven fabric; a knitted fabric; a fiber bundle; a cylinder including a fiber bundle and a tube into which the fiber bundle is inserted; or a combination of two or more thereof. 8. The method of claim 7 , wherein the subjecting of the dispersion to natural sedimentation is performed in a temperature range of 20-30° C. for 12-36 hours.
Assignees
Inventors
Classifications
characterised by a special physical form · CPC title
Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines · CPC title
Glycosaminoglycans, e.g. heparin, hyaluronic acid, chondroitin · CPC title
Tissue-regenerating or healing or proliferative agents · CPC title
Polysaccharides · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US12005152B2 cover?
- The present disclosure relates to a microgel composition comprising collagen and hyaluronic acid and a method of preparing the same. The microgel according to an embodiment is composed of natural biocompatible substances and is non-toxic and has high mechanical stability or long persistence, and thus can be effectively used in a microgel composition, a three-dimensional scaffold composition, an…
- Who is the assignee on this patent?
- Korea Inst Sci & Tech
- What technology area does this patent fall under?
- Primary CPC classification A61L26/008. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jun 11 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).