Catheter design for use in treating pleural diseases

Patent metadata

Field	Value
Publication number	US-12004770-B2
Application number	US-202017068593-A
Country	US
Kind code	B2
Filing date	Oct 12, 2020
Priority date	May 7, 2010
Publication date	Jun 11, 2024
Grant date	Jun 11, 2024

Abstract

A catheter for use in treating pleural diseases, such as pleural effusions and pneumothorax, includes a tip portion that is configured to irritate the pleura when the catheter is inserted in the pleural cavity, thereby initiating mechanical pleurodesis. The tip portion has a substantially rough configuration and may include one or more protrusions that contact the pleura when the catheter is in use, thereby irritating the layers. This irritation causes the creation of fibrous adhesions between the parietal and visceral layers that close off the pleural cavity and prevent further fluid and/or air accumulations that occur as a result of pleural diseases.

First claim

What is claimed is:

1. A method of removing fluid and performing mechanical pleurodesis comprising:
inserting a catheter into a patient's pleural cavity, the catheter comprising a lumen and an outer wall at least partially surrounding the lumen with an external surface extending from a proximal end of the catheter to an opening of the lumen at a distal most tip of the catheter, wherein a distal end portion of the external surface of the catheter comprises a plurality of protrusions thereon;
using the lumen of the catheter to remove pleural fluid from the patient's pleural cavity; and
performing mechanical pleurodesis by irritating tissue of the pleural cavity to promote the creation of fibrous adhesions between visceral layers of the pleural cavity, wherein the mechanical pleurodesis is performed by moving the distal end portion of the catheter within the pleural cavity to cause contact between the plurality of protrusions and tissue of the pleural cavity.

2. The method of claim 1 , wherein the irritation caused by the plurality of protrusions at the distal end portion causes the creation of fibrous adhesions between a parietal and a visceral layer of the patient's pleura.

3. The method of claim 1 , wherein the removed pleural fluid is collected in a drainage container.

4. The method of claim 1 , wherein the catheter is formed of a material sufficiently rigid so that the protrusions are able to irritate the tissue of the pleural cavity.

5. The method of claim 4 , wherein the material is at least one of a silicone, polyvinyl chloride (PVC), polypropylene, polyurethane, or a thermoplastic elastomer.

6. The method of claim 1 , wherein the positioning of the catheter in the patient's body is assisted via use of a cuff that surrounds the outer wall of the catheter.

7. The method of claim 1 , wherein tissue that contacts protrusions at the distal end portion closest the distal most tip portion of the catheter is roughened less than tissue that contacts protrusions further from the distal most tip portion of the catheter.

8. The method of claim 7 , wherein at least one of a size or shape of the plurality of protrusions are varied along a length of the distal end portion such that larger protrusions are provided at a proximal end thereof and smaller protrusions are present at a distal end closest to the tip portion of the catheter.

9. The method of claim 1 , wherein the distal end portion extends from the tip of the catheter.

10. The method of claim 1 , wherein the protrusions have a shape selected from a group consisting of circular, elliptical, triangular, rectangular, or other polygonal.

11. A method of performing mechanical pleurodesis comprising:
inserting a catheter into a patient's pleural cavity, the catheter comprising a lumen and an outer wall at least partially surrounding the lumen with an external surface extending from a proximal end of the catheter to an opening of the lumen at a distal most tip of the catheter, wherein a distal end portion of the external surface of the catheter comprises a plurality of protrusions thereon;
performing mechanical pleurodesis by irritating tissue of the pleural cavity to promote the creation of fibrous adhesions between visceral layers of the pleural cavity, wherein the mechanical pleurodesis is performed by moving the distal end portion of the catheter within the pleural cavity to cause contact between the plurality of protrusions and tissue of the pleural cavity; and
using the lumen of the catheter to remove pleural fluid from the patient's plural cavity.

12. The method of claim 11 , wherein the removed pleural fluid is collected in a drainage container.

13. The method of claim 11 , wherein the irritation caused by the plurality of protrusions at the distal end portion causes the creation of fibrous adhesions between a parietal and a visceral layer of the pleura.

14. The method of claim 11 , wherein the catheter is formed of a material sufficiently rigid so that the protrusions are able to irritate the tissue of the pleural cavity.

15. The method of claim 12 , wherein the material is at least one of a silicone, polyvinyl chloride (PVC), polypropylene, polyurethane, or a thermoplastic elastomer.

16. An apparatus for removing fluid and performing mechanical pleurodesis between a parietal and a visceral layer of a patient's pleura, the apparatus comprising:
an elongated tubular member that extends between a proximal end and a distal most tip;
a lumen; and
an outer wall at least partially surrounding the lumen with an external surface extending from the proximal end of the tubular member to an opening of the lumen at a distal most tip of the of the tubular member, wherein a distal end portion of the external surface of the tubular member comprises a plurality of protrusions thereon, wherein the tubular member is configured to be inserted into a patient's pleural cavity to remove pleural fluid from the patients pleural cavity via the lumen and the plurality of protrusions at the distal end portion are used to irritate tissue of the pleural cavity to promote the creation of fibrous adhesions between the parietal and a visceral layer of the patient's pleura, wherein the mechanical pleurodesis is performed by moving the distal end portion of the tubular member within the pleural cavity to cause contact between the plurality of protrusions and tissue of the pleural cavity.

17. The apparatus of claim 16 , wherein the tubular member is formed of a material sufficiently rigid so that the protrusions are able to irritate the tissue of the pleural cavity.

18. The apparatus of claim 17 , wherein the material is at least one of a silicone, polyvinyl chloride (PVC), polypropylene, polyurethane, or a thermoplastic elastomer.

19. The apparatus of claim 16 , further comprising a cuff that surrounds the outer wall of the elongated tubular member, wherein the positioning of the elongated tubular member in the patient's body is assisted via use of the cuff.

20. The apparatus of claim 16 , wherein at least one of a size or shape of the plurality of protrusions are varied along a length of the distal end portion such that larger protrusions are provided at a proximal end thereof and smaller protrusions are present at a distal end closest to the tip portion of the tubular member.

21. The apparatus of claim 16 , wherein the protrusions have a shape selected from a group consisting of circular, elliptical, triangular, rectangular, or other polygonal.

Assignees

• Carefusion 2200 Inc

Inventors

• Looper Anthony
• Krueger John A
• Schmitt Jeffrey

Classifications

• A61M16/0406

  implanted flow modifiers · CPC title

• A61M2210/101

  Pleural cavity · CPC title

• A61M25/0068 Primary

  Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure · CPC title

• A61M2025/0096

  being laterally outward extensions or tools, e.g. hooks or fibres · CPC title

• A61M2025/006

  having a special surface topography or special surface properties, e.g. roughened or knurled surface · CPC title