System and method for wirelessly powering a sensor in a bio-processing environment

Patent metadata

Field	Value
Publication number	US-11987783-B2
Application number	US-201816607544-A
Country	US
Kind code	B2
Filing date	Apr 18, 2018
Priority date	Apr 28, 2017
Publication date	May 21, 2024
Grant date	May 21, 2024

Abstract

A bio-processing system ( 100 ) for wirelessly powering one or more sensors ( 116 - 128, 400 ) is presented. The system ( 100 ) includes bio-processing units ( 106 - 110 ), process supporting devices ( 112 - 114 ), energy sources ( 146 - 148 ), and sensors ( 116 - 128, 400 ) including an energy harvesting unit ( 402 ) and an energy storage unit ( 404 ). The system ( 100 ) includes a power management subsystem ( 104, 200 ) wirelessly coupled to the sensors ( 116 - 128, 400 ) and including a processor ( 202 ) configured to wirelessly monitor energy consumption of the sensors ( 116 - 128, 400 ) and a level of energy stored in corresponding energy storage units ( 404 ), select at least one sensor ( 116 - 128, 400 ) based on the energy consumption of the sensors ( 116 - 128, 400 ) and corresponding levels of energy stored in the energy storage units ( 404 ), and identify at least one active energy source ( 146 - 148 ) as a power source, where the identified power source is configured to wirelessly transfer power to the selected sensor ( 116 - 128, 400 ).

First claim

The invention claimed is:

1. A bio-processing system for wirelessly powering one or more sensors, the system comprising:
one or more bio-processing units configured to perform at least one bio-processing operation;
one or more process supporting devices operatively coupled to the one or more bio-processing units, wherein the one or more process supporting devices are configured to aid the one or more bio-processing units in performing the at least one bio-processing operation;
one or more energy sources, wherein the one or more energy sources comprise one or more active energy sources and one or more ambient energy sources;
one or more sensors operatively coupled to at least one of the one or more bio-processing units and the one or more process supporting devices, wherein at least one sensor of the one or more sensors comprises:
an energy harvesting unit configured to harvest energy from at least one energy source of the one or more energy sources, and
an energy storage unit operatively coupled to the energy harvesting unit and configured to store the harvested energy;

a power management subsystem wirelessly coupled to the one or more sensors, wherein the power management subsystem comprises a processor configured to:
wirelessly monitor energy consumption of the one or more sensors and a level of energy stored in corresponding energy storage units of the one or more sensors;
select at least one energy-deficient sensor being unable to power itself and enable a self-sustaining sensor operation of the one or more sensors based on the energy consumption of the one or more sensors and corresponding levels of energy stored in the energy storage units of the one or more sensors; and
identify at least one active energy source of the one or more active energy sources as a power source, wherein the identified power source is configured to wirelessly transfer power to the selected at least one energy-deficient sensor.

2. The bio-processing system of claim 1 , wherein the one or more bio-processing units comprise one or more disposable components formed using a polymeric material.

3. The bio-processing system of claim 2 , wherein the one or more sensors are disposed on one or more of the one or more disposable components of the one or more bio-processing units and disposable flexible tubing used to operatively couple the one or more bio-processing units and the one or more process supporting devices in the bio-processing system.

4. The bio-processing system of claim 1 , wherein the one or more sensors comprise a pressure sensor, a temperature sensor, a pH sensor, a conductivity sensor, a glucose sensor, a biomass sensor, a cell viability sensor, an oxygen sensor, a carbon-dioxide sensor, an ultraviolet sensor, a flow sensor, a foam sensor, or combinations thereof.

5. The bio-processing system of claim 1 , wherein to identify the at least one active energy source of the one or more active energy sources as the power source, the processor is further configured to:
generate a power management user interface based on the one or more sensors, the one or more energy sources, the energy consumption of the at least one sensor, and the level of energy stored in the energy storage unit of the at least one sensor, wherein the power management user interface comprises one or more recommendations for powering the at least one sensor;
visualize the power management user interface on a display unit of the power management subsystem;
receive control inputs via the power management user interface; and
activate the identified power source based on the control inputs to power the selected at least one sensor.

6. The bio-processing system of claim 5 , wherein to generate the power management user interface the processor is configured to:
obtain a desirable power for powering the at least one sensor;
compare the level of energy stored in the energy storage unit of the at least one sensor with the desirable power corresponding to the at least one sensor; and
create, based on the comparison, one or more recommendations for identifying the at least one active energy source as the power source for powering the at least one sensor.

7. The bio-processing system of claim 1 , wherein the at least one sensor further comprises a power converter disposed between the energy harvesting unit and the energy storage unit, and wherein the power converter is configured to enhance a level of the harvested energy.

8. The bio-processing system of claim 1 , wherein the at least one sensor further comprises:
a sensing unit configured to sense a process parameter corresponding to the at least one bio-processing operation; and
a wireless communication unit operatively coupled to the sensing unit and configured to communicate data corresponding to the sensed process parameter to the processor,
wherein the sensing unit and the wireless communication unit are powered via the stored energy in the energy storage unit.

9. The bio-processing system of claim 1 , wherein the energy harvesting unit comprises a thermo-electric generator, a Peltier element, a photovoltaic module, an electromagnetic power generation module, a piezo electric device, an inductive device, or combinations thereof, and the energy storage unit includes a rechargeable battery, a solid-state battery, a capacitor, a super-capacitor, an ultra-capacitor, or a combination thereof.

10. The bio-processing system of claim 1 , wherein the power management subsystem further comprises a master wireless communication unit configured to aid in wireless communication between the processor and the one or more energy sources to activate the identified power source to power the at least one sensor.

11. The bio-processing system of claim 1 , further comprising a smart switching device configured to operatively couple the processor to the one or more energy sources, wherein the smart switching device is configured to activate the identified power source.

12. The bio-processing system of claim 1 , wherein the one or more active energy sources comprise a radio frequency source, a light source, a heat source, a vibration source, an ultrasound energy source, or combinations thereof.

13. The bio-processing system of claim 1 , wherein the one or more ambient energy sources comprise an ambient temperature, an ambient pressure, an ambient light, an ambient radio frequency source, or combinations thereof.

14. The bio-processing system of claim 1 , wherein the one or more bio-processing units comprise a bioreactor for cell cultivation, a wave rocker, a cell banking unit, a cell harvesting unit, a chromatography unit, a protein concentration unit, a sterile filtration unit, a virus removal unit, a product holding unit, a buffer preparation unit, a media preparation unit, a buffer holding unit, a media holding unit, or combinations thereof, and the one or more process supporting devices comprise a pump, a weighing scale, a flow restriction clamp, a temperature management device, or combinations thereof.

15. A method for wirelessly powering one or more sensors in a bio-processing system comprising one or more bio-processing units, one or more process supporting devices, the one or more sensors, one or more energy sources, and a power management subsystem, the method comprising:
wirelessly harvesting, via an energy harvesting unit in the one or more sensors, energy from at least one energy source of the one or more energy sources in the bio-processing system, wherein the one more energy sources comprise one or more active energy sources and one or more ambient energy sources;
storing, via an energy storage unit in the one o

Assignees

• Cytiva Sweden Ab

Inventors

• Bhat Suma Memana Narayana
• Rao Veena B N
• Axen Andreas
• Aravind Deepak
• Kavoori Sethumadhavan Nagapriya
• Lakhani Hanish
• Halder Purbasha
• Jose Victor

Classifications

• H02J7/42

  with electronic devices having internal batteries, e.g. mobile phones · CPC title

• C12M27/16 Primary

  Vibrating; Shaking; Tilting · CPC title

• C12M21/02

  Photobioreactors (culturing algae A01G33/00, A01H4/001, C12N1/12) · CPC title

• C12M43/08

  Bioreactors or fermenters combined with devices or plants for production of electricity · CPC title

• C12M47/02

  Separating microorganisms from the culture medium; Concentration of biomass (separating microorganisms from their culture media C12N1/02) · CPC title