Surgical applications with integrated visualization camera and optical coherence tomography

Patent metadata

Field	Value
Publication number	US-11986240-B2
Application number	US-202017108481-A
Country	US
Kind code	B2
Filing date	Dec 1, 2020
Priority date	Dec 5, 2019
Publication date	May 21, 2024
Grant date	May 21, 2024

Abstract

A system for guiding an ophthalmic procedure is disclosed. The system includes a housing assembly with a head unit configured to be at least partially directed towards a target site in an eye. An optical coherence tomography (OCT) module and stereoscopic visualization camera are at least partially located in the head unit and configured to obtain a first set and a second set of volumetric data, respectively. A controller is configured to register the first set and second set of volumetric data to create a third set of registered volumetric data. The third set and second set of registered volumetric data are rendered, via a volumetric render module, to a first and second region. The first region and the second region are overlaid to obtain a shared composite view of the target site. The controller is configured to extract structural features and/or enable visualization of the target site.

First claim

What is claimed is:

1. A system for guiding an ophthalmic procedure, the system comprising:
a housing assembly having a head unit configured to be at least partially directed towards a target site in an eye;
an optical coherence tomography (OCT) module at least partially located in the head unit and configured to obtain a first set of volumetric data of the target site;
a stereoscopic visualization camera at least partially located in the head unit and configured to obtain a second set of volumetric data of the target site, the second set of volumetric data including first and second views of the target site;
a controller in communication with the stereoscopic visualization camera and the OCT module;
a volumetric render module selectively executable by the controller;
wherein the controller has a processor and tangible, non-transitory memory on which instructions are recorded, execution of the instructions causing the controller to:
register the first set of volumetric data from the OCT module with the second set of volumetric data from the stereoscopic visualization camera to create a third set of registered volumetric data;
render the third set of registered volumetric data to a first region to obtain a two-dimensional OCT view, via the volumetric render module;
render the second set of volumetric data from the stereoscopic visualization camera to a second region to obtain a live two-dimensional stereoscopic view, via the volumetric render module;
obtain a plurality of depth scans extending through a corneal surface, each of the plurality of depth scans defining respective starting points;
collect respective three-dimensional locations corresponding to the respective starting points of the plurality of depth scans as a point cloud, and convert the point cloud to obtain an extracted curvature, including interpolating between the respective starting points; and
overlay the first region and the second region to obtain a shared composite view of the target site and at least one of visualize and extract features of the target site.

2. The system of claim 1 , wherein:
the extracted curvature is characterized by a plurality of depths; and
the controller is configured to visualize the shared composite view with a plurality of topographic levels; and
the plurality of topographic levels respectively represent the plurality of depths such that the extracted curvature may be visualized.

3. The system of claim 1 , wherein:
the ophthalmic procedure is a cataract surgery including implantation of an intraocular lens into an eye;
the controller is configured to add at least one annotation over the shared composite view on a display, the at least one annotation indicating the extracted curvature;
to maintain a relative position of the at least one annotation in the shared composite view; and
employ the extracted curvature to guide alignment of an intraocular device to the eye.

4. The system of claim 3 , wherein:
the first set of volumetric data is configured to be updated at a first frequency and the second set of volumetric data is configured to be updated at a second frequency; and
the updating of the first set of volumetric data and the second set of volumetric data is synchronized to facilitate the alignment of the intraocular device to the eye.

5. The system of claim 1 , wherein:
the controller is configured to obtain respective axial length measurements in real time repeatedly during the ophthalmic procedure by switching the OCT module between a first resolution mode and a second resolution mode.

6. The system of claim 1 , further comprising:
a robotic arm operatively connected to and configured to selectively move the head unit; and
wherein the robotic arm is selectively operable to extend a viewing range of the OCT module in an axial direction, a first transverse direction and a second transverse direction.

7. The system of claim 1 , wherein:
the stereoscopic visualization camera and the OCT module define a respective latency;
the controller includes a first set of image buffers configured to selectively delay a display of the two-dimensional OCT view to match the respective latency of the stereoscopic visualization camera; and
the controller includes a second set of image buffers configured to selectively delay the display of the live two-dimensional stereoscopic view to match the respective latency of the OCT module.

8. The system of claim 1 , wherein the controller is configured to:
add at least one annotation over the shared composite view on a display, the at least one annotation indicating a landmark of the eye; and
to maintain a relative position of the at least one annotation in the live two-dimensional stereoscopic view.

9. The system of claim 1 , wherein registering the first set of volumetric data from the OCT module with the second set of volumetric data from the stereoscopic visualization camera includes:
aligning the first and second views of the stereoscopic visualization camera respectively in rotation, translation and scale to the volumetric render module; and
matching respective perspectives of the first and second views of the stereoscopic visualization camera to the volumetric render module.

10. The system of claim 1 , wherein registering the first set of volumetric data with the second set of volumetric data includes:
finding a respective location and respective orientation of a center of projection of a first two-dimensional visualization module and a second two-dimensional visualization module of the stereoscopic visualization camera relative to the respective location and the respective orientation of a respective data space of the OCT module.

11. The system of claim 1 , wherein registering the first set of volumetric data with the second set of volumetric data includes:
aligning a local area of interest in the first set of volumetric data in position, orientation and size with the second set of volumetric data; and
wherein the local area of interest includes at least one of a corneal limbus and a scleral vasculature.

12. The system of claim 1 , wherein prior to registering the first set of volumetric data with the second set of volumetric data, the controller is configured to:
calibrate the OCT module and calibrate the stereoscopic visualization camera, including placing a calibration device at the target site and fitting respective lines to respective surfaces of the calibration device in each of three orthogonal views.

13. The system of claim 1 , further comprising:
an oblique visualization module selectively executable by the controller to produce an off-axis view of the shared composite view such that a respective representation of the first set of volumetric data and the second set of volumetric data is viewed at a predefined oblique angle; and
wherein execution of the oblique visualization module causes the controller to:
form a virtual image based in part on the first set of volumetric data;
render the virtual image as a first pair of stereo images;
render the second set of volumetric data as a second pair of stereo images; and
fuse the first pair of stereo images and the second pair of stereo images to form the off-axis view.

14. The system of claim 13 , wherein:
the predefined oblique angle is selectable by a user via a user interface.

15. A system for guiding an ophthalmic procedure, the system comprising:
a housing assembly having a head unit configured to be at least partially directed towards a target site in an eye;
an optical coherence tomography (OCT) module at least partially located in the head unit and configu

Assignees

• Alcon Inc

Inventors

• Tripathi Ashok Burton
• Polchin George Charles
• Ramirez Luna Maximiliano
• Terry Patrick
• Riederer Thomas Paul

Classifications

• A61B3/102 Primary

  for optical coherence tomography [OCT] · CPC title

• A61B3/08

  for testing binocular or stereoscopic vision, e.g. strabismus · CPC title

• A61B3/107

  for determining the shape or measuring the curvature of the cornea · CPC title

• A61F9/00736

  Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments (A61F9/008 takes precedence) · CPC title

• A61F9/00834

  Inlays; Onlays; Intraocular lenses [IOL] · CPC title