Tissue collection device for catheter

Patent metadata

Field	Value
Publication number	US-11980386-B2
Application number	US-202117445648-A
Country	US
Kind code	B2
Filing date	Aug 23, 2021
Priority date	Mar 15, 2013
Publication date	May 14, 2024
Grant date	May 14, 2024

Abstract

Versatile tissue collection devices that can provide reduced crossing profiles, fluid pressure release, and/or easy cleaning or removal. In particular, devices having tissue collection devices with multiple configurations to facilitate navigation through narrow vessel cross-sections while also providing adequate tissue storage capacity. Additionally, the devices may include detachable components that allow easy removal, cleaning, and replacement during a procedure. Furthermore, venting elements and sections may be included to relieve fluid buildup in storage reservoirs.

First claim

What is claimed is:

1. A tissue collection device comprising:
a proximal end and a distal end defining a length of the device;
a shaft located along at least a portion of the length, the shaft defining a lumen;
a tendon member residing in the shaft lumen; and
a tissue storage reservoir having an adjustable cross-section, wherein the tissue storage reservoir is movable between a first configuration and a second configuration, the second configuration having a smaller crossing profile and a reduced cross-section relative to the first configuration,
wherein the proximal end is adapted to couple to a catheter and further comprises an opening configured to communicate with the catheter when the catheter is coupled thereto such that excised tissue from the catheter can enter the tissue storage reservoir, and
wherein the tissue storage reservoir comprises a plurality of gaps having a width from 50 μm to 200 μm.

2. The device of claim 1 , wherein the tissue storage reservoir is configured to compress when moved to the second configuration and expand when moved to the first configuration.

3. The device of claim 1 , wherein the tissue storage reservoir comprises a mesh, the mesh configured to collapse when the tissue storage reservoir is moved from the first configuration to the second configuration.

4. The device of claim 1 , wherein the tissue storage reservoir comprises a wire frame that is configured to collapse when the tissue storage reservoir moves from the first configuration to the second configuration.

5. The device of claim 1 , wherein the tissue storage reservoir is formed from a braided nitinol mesh that is configured to collapse and expand between the first and second configurations.

6. The device of claim 1 , wherein the tissue storage reservoir comprises an elastic material.

7. The device of claim 1 , wherein the tissue storage reservoir comprises a resilient material.

8. The device of claim 1 , wherein the tissue storage reservoir comprises a shape-memory material.

9. The device of claim 1 , wherein the tissue storage reservoir is configured to move from the first configuration to the second configuration by applying a distally directed force along a longitudinal axis of the device.

10. The device of claim 9 , wherein the distally directed force is applied to the distal end of the device.

11. The device of claim 1 , wherein the tissue storage reservoir is configured to move from the first configuration to the second configuration by extending the length of the device.

12. The device of claim 1 , further comprising a guidewire lumen and a guidewire residing in the guidewire lumen, wherein distally moving the guidewire against the distal end of the device applies a distally directed force to thereby move the tissue storage reservoir from the first configuration to the second configuration.

13. The device of claim 12 , wherein the tissue storage reservoir is configured to return to the first configuration from the second configuration after the distal force is released.

14. The device of claim 12 , wherein the tissue storage reservoir is configured to return to the first configuration from the second configuration by applying a proximally directed force at the distal end.

15. The device of claim 1 , wherein the first configuration has a crossing profile of 0.080 inches.

16. The device of claim 1 , wherein the second configuration has a crossing profile of 0.020 inches.

17. The device of claim 1 , wherein the length is from 10 mm to 100 mm.

18. The device of claim 1 , wherein a crossing profile of the tip portion is from 0.020 inches to 0.080 inches.

19. The device of claim 1 , wherein the tissue storage reservoir comprises a porous member configured to allow fluid movement out of the storage reservoir.

20. The device of claim 1 , the tissue storage reservoir further comprising a third configuration, the third configuration having a greater crossing profile relative to the first configuration.

21. The device of claim 1 , wherein the tissue storage reservoir is adapted to be biased towards the first configuration.

22. The device of claim 1 , wherein the device is configured such that distally moving the tendon member against a distal end of the device applies a distally directed force to thereby move the tissue storage reservoir from the first configuration to the second configuration.

23. The device of claim 22 , wherein the device is configured such that proximally moving the tendon member moves the tissue storage reservoir from the second configuration to the first configuration.

24. The device of claim 1 , wherein the tissue storage reservoir has a distal end and a proximal end, and the distal end of the tissue storage reservoir is fixed to the tendon member and the proximal end of the tissue storage reservoir is fixed to the shaft.

25. The device of claim 24 , wherein the tissue storage reservoir is adapted to transition to the second configuration by distally moving the tendon member relative to the shaft.

26. The device of claim 24 , wherein the tissue storage reservoir is adapted to transition to the second configuration by rotating the tissue storage reservoir about the shaft to form a coiled collapsed configuration.

27. The device of claim 24 , wherein the tissue storage reservoir comprises a resilient frame configured to naturally return to the first configuration.

28. A tissue collection device comprising:
a proximal end and a distal end defining a length of the device;
a shaft located along at least a portion of the length, the shaft defining a lumen;
a tendon member residing in the shaft lumen; and
a tissue storage reservoir having an adjustable cross-section, wherein the tissue storage reservoir is movable between a first configuration and a second configuration, the second configuration having a smaller crossing profile and a reduced cross-section relative to the first configuration,
wherein the proximal end is adapted to couple to a catheter, and wherein the proximal end further comprises an opening configured to communicate with the catheter when the catheter is coupled thereto such that excised tissue from the catheter can enter the tissue storage reservoir, and
wherein the tissue storage reservoir comprises a plurality of gaps of between 0.01 mm to 0.5 mm.

Assignees

• Avinger Inc

Inventors

• Gupta Priyanshu
• Van Christina
• Spinelli Nicholas J
• Simpson John B

Classifications

• A61B17/320783 Primary

  through side-hole, e.g. sliding or rotating cutter inside catheter · CPC title

• A61B10/0275

  with sample notch, e.g. on the side of inner stylet · CPC title

• A61B2017/320064

  with tissue or sample retaining means · CPC title

• A61B2017/320791

  with cutter extending outside the cutting window · CPC title