Novel Chiral Alfa-Amino Tertiary Boronic Esters
US-2020079799-A1 · Mar 12, 2020 · US
US11970432B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11970432-B2 |
| Application number | US-202318175740-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 28, 2023 |
| Priority date | Jun 7, 2021 |
| Publication date | Apr 30, 2024 |
| Grant date | Apr 30, 2024 |
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
What the patent document calls the invention.
A short plain-language summary of the technical disclosure.
Who owns or filed the patent and who is credited as inventor.
Filing, priority, publication, and grant dates set the timeline.
The legal scope of protection — read this for what is actually claimed.
Technology tags used to group this patent with similar filings.
Prior art links and similar publications in this corpus.
Official abstract text for this publication.
The present invention provides a process for preparing 2-methyl-N-(2′-methylbutyl)butanamide of the following formula (1): the process comprising: subjecting an α-arylethyl-2-methylbutylamine compound of the following general formula (2): wherein Ar represents a substituted or unsubstituted aryl group having 6 to 20 carbon atoms, to N-2-methylbutyrylation to form an N-α-arylethyl-2-methyl-N-(2′-methylbutyl)butanamide compound of the following general formula (3): wherein Ar is as defined above, and removing the α-arylethyl group of the resulting compound (3) to form 2-methyl-N-(2′-methylbutyl)butanamide (1).
Opening claim text (preview).
The invention claimed is: 1. A process for preparing a mixture of diastereomers of general formulae (2R*,αR*)-(2) and (2S*,αR*)-(2) of an α-arylethylamine compound: wherein the hashed bond and the bold bonds represent a relative configuration, and Ar represents a substituted or unsubstituted aryl group having 6 to 20 carbon atoms, the process comprising: separating the mixture of the diastereomers of general formulae (2R*,αR*)-(2) and (2S*,αR*)-(2) of the α-arylethylamine compound from an α-arylethyl-2-methylbutylamine compound of general formula (2): wherein Ar of general formula (2) represents a substituted or unsubstituted aryl group having 6 to 20 carbon atoms.
by formation of carboxamide groups together with reactions not involving the carboxamide groups · CPC title
by separation of optical isomers · CPC title
from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines · CPC title
Optical isomers · CPC title
by reactions not involving the formation of carboxamide groups · CPC title
Related publications grouped by family.
Answers are generated from the same data shown on this page.