Milk protein concentrate-based microencapsulation wall material and microcapsules

Patent metadata

Field	Value
Publication number	US-11964249-B2
Application number	US-202017123415-A
Country	US
Kind code	B2
Filing date	Dec 16, 2020
Priority date	Jun 27, 2018
Publication date	Apr 23, 2024
Grant date	Apr 23, 2024

Abstract

The disclosure discloses a milk protein concentrate-based microencapsulation wall material and microcapsules, and belongs to the technical field of microcapsule preparation. In the disclosure, liquid or solid microcapsules are prepared by performing cation exchange treatment on milk protein concentrates, and then using the treated milk protein concentrates as a wall material. The prepared microcapsules have good physical and chemical stability during storage, and are suitable for protecting active functional factors and to be applied in the fields of food, medicine, health care products, cosmetics, daily chemicals and the like.

First claim

What is claimed is:

1. A microcapsule, comprising:
a wall material, and
a core material,
wherein the wall material comprises a pretreated milk protein concentrate (MPC),
wherein the core material comprises one or more of vitamins, unsaturated fatty acids, probiotics, vaccines, and essential oils; and
wherein the pretreated MPC is prepared by subjecting the MPC to any one or more of the following:
a) stirring ion exchange resin with the MPC,
b) adding an acid to the MPC, wherein the acid is selected from one or more of hydrochloric acid, sulfuric acid, acetic acid, and glucolactone, and then subjecting the MPC to ultrafiltration, and
c) adding a calcium ion chelator to the MPC, wherein the chelator is selected from one or more of ethylene diamine tetraacetic acid (EDTA), citric acid, malic acid, and tartrate.

2. The microcapsule of claim 1 , wherein a mass ratio of the ion exchange resin to the MPC in dry weight is 1:30 to 3:1.

3. The microcapsule of claim 1 , wherein stirring the ion exchange resin with the MPC is performed and comprises:
adding 0.1 g to 30 g of the ion exchange resin to 100 g of the MPC to obtain a mixed solution, and
stirring the mixed solution for a period of time for treatment.

4. The microcapsule of claim 1 , wherein the pretreatment is performed until a decalcification rate is 45% or above.

5. The microcapsule of claim 1 , wherein when the ion exchange resin is used, a mass ratio of the ion exchange resin to the MPC in dry weight is 1:30 to 3:1; and wherein the pretreatment is performed until a decalcification rate is 45% or above.

6. The microcapsule of claim 1 , wherein preparing the microcapsule comprises:
homogenizing the pretreated MPC at 10 Mpa to 50 MPa,
adding the core material according to a mass ratio of the core material to the wall material of 1:50 to 1:1 (w/w);
stirring,
dispersing by a high-speed shearing disperser; and
homogenizing the mixture 2 to 6 times at a pressure of 10 MPa to 50 MPa to obtain a uniform emulsion.

7. The microcapsule of claim 6 , wherein wherein preparing the microcapsule further comprises:
spray-drying or freeze-drying the uniform emulsion to prepare microcapsule powder;
wherein the spray-drying is performed at an inlet temperature of 120° C. to 160° C. and an outlet temperature controlled at 60° C. to 90° C.; and
wherein the freeze-drying is performed by freezing the emulsion into a solid state under liquid nitrogen or at −80° C.

8. The microcapsule of claim 1 , wherein an encapsulation rate of the core material is from about 84.4% to about 96.3%.

9. The microcapsule of claim 1 , wherein the core material is an unsaturated fatty acid.

10. The microcapsule of claim 6 , wherein the microcapsule emulsion forms a continuous viscoelastic interface.

Assignees

• Univ Jiangnan

Inventors

• Zhou Peng
• Hu Jinhua
• Zhuang Fengchen
• Li Xiang
• Jin Yuejie
• Zhang Chaoyue
• Cheng Minjun
• Liang Yongxue

Classifications

• B01J13/04 Primary

  by physical processes, e.g. drying, spraying · CPC title

• B01D15/361

  Ion-exchange · CPC title

• B01F23/4105

  Methods of emulsifying · CPC title

• B01F23/804

  Drying the mixture · CPC title

• B01F23/809

  Freezing the mixture · CPC title