Compositions comprising constituents, derivatives or extracts of cannabis
US-2024415913-A1 · Dec 19, 2024 · US
Use of cannabinoids in the treatment of a neurodegenerative disease or disorder
US11944600B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11944600-B2 |
| Application number | US-201816629722-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 10, 2018 |
| Priority date | Jul 12, 2017 |
| Publication date | Apr 2, 2024 |
| Grant date | Apr 2, 2024 |
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- Title
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Abstract
Official abstract text for this publication.
The present invention relates to the use of cannabinoids in the treatment of a neurodegenerative disease or disorder. In particular the cannabinoids cannabidiolic acid (CBDA) and cannabidivarin (CBDV) were able to produce neuroprotective effects in a mouse model of neurodegenerative disease. In particular these effects were associated with the symptoms associated with amyotrophic lateral sclerosis (ALS). Furthermore, the combination of the cannabinoid tetrahydrocannabinol (THC) with the drug olexisome provided a synergistic disease modifying effect in a mouse model of neurodegenerative disease. In particular these effects were associated with the symptoms associated with ALS.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method of treating a patient with amyotrophic lateral sclerosis (ALS) comprising administering to the patient tetrahydrocannabinol (THC) in combination with olesoxime. 2. The method of claim 1 , wherein the THC is present as an extract of a cannabis plant. 3. The method of claim 2 , wherein the extract of the cannabis plant is a botanical drug substance (BDS). 4. The method of claim 1 , wherein the THC is present as a highly purified, isolated or synthetic cannabinoid. 5. The method of claim 2 , wherein the THC is present as a highly purified, isolated or synthetic cannabinoid.
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Classifications
Cannabis · CPC title
- A61K31/658Primary
o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol · CPC title
having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid {(cannabinoids A61K31/658)} · CPC title
3,4-Dihydrobenzopyrans, e.g. chroman, catechin · CPC title
substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol · CPC title
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- What does patent US11944600B2 cover?
- The present invention relates to the use of cannabinoids in the treatment of a neurodegenerative disease or disorder. In particular the cannabinoids cannabidiolic acid (CBDA) and cannabidivarin (CBDV) were able to produce neuroprotective effects in a mouse model of neurodegenerative disease. In particular these effects were associated with the symptoms associated with amyotrophic lateral sclero…
- Who is the assignee on this patent?
- Gw Res Ltd
- What technology area does this patent fall under?
- Primary CPC classification A61K31/658. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Apr 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).