Living body internal temperature measuring device and living body internal temperature measuring method

Patent metadata

Field	Value
Publication number	US-11940333-B2
Application number	US-201917058555-A
Country	US
Kind code	B2
Filing date	May 14, 2019
Priority date	May 28, 2018
Publication date	Mar 26, 2024
Grant date	Mar 26, 2024

Abstract

A heat flux sensor including two temperature sensors is used to obtain time-series data of a core temperature of a living body, and a blood flow rate in a vicinity of the heat flux sensor is measured by a blood flow sensor. In an arithmetic circuit, a delay time until a fluctuation of the core temperature of the living body is reflected on an epidermis temperature is calculated on the basis of the blood flow rate measured by the blood flow sensor and a previously prepared relation between the blood flow rate and the delay time until the fluctuation of the core temperature of the living body is reflected on the epidermis temperature, and a time corresponding to the core temperature of the living body on the basis of the delay time is corrected.

First claim

The invention claimed is:

1. An internal body temperature measurement device comprising:
a temperature sensor configured to measure an epidermis temperature of a living body;
a heat flux sensor configured to measure a magnitude of a heat flux discharged from a body surface of the living body;
a blood flow sensor configured to measure a blood flow rate in a vicinity of the heat flux sensor;
a non-transitory memory which stores a relation between a plurality of different blood flow rates of the living body and a parameter, the parameter defining a respective delay time until a fluctuation of a core temperature of the living body is reflected on the epidermis temperature of the living body for each of the plurality of different blood flow rates; and
an arithmetic circuit configured to:
calculate the core temperature of the living body from the epidermis temperature and the magnitude of the heat flux;
calculate a delay time corresponding to the epidermis temperature measured by the temperature sensor by correlating the blood flow rate measured by the blood flow sensor in the vicinity of the heat flux sensor and the relation between the plurality of different blood flow rates and the parameter stored in non-transitory memory; and
correct a time corresponding to the core temperature of the living body based on the delay time, wherein correcting the time corresponding to the core temperature of the living body based on the delay time comprises correcting the time corresponding to the core temperature of the living body based on the delay time that is less than a predetermined threshold.

2. The internal body temperature measurement device according to claim 1 , wherein the arithmetic circuit includes:
a first calculator which calculates the core temperature of the living body from the epidermis temperature and the magnitude of the heat flux,
a second calculator which calculates the delay time based on of the blood flow rate in the vicinity of the heat flux sensor and the relation stored in the non-transitory memory, and
a corrector which corrects the time corresponding to the core temperature of the living body based on the delay time.

3. The internal body temperature measurement device according to claim 1 , wherein the parameter is a time constant of a fluctuation of the epidermis temperature with respect to the fluctuation of the core temperature of the living body or the delay time.

4. The internal body temperature measurement device according to claim 1 , further comprising:
a first blood flow sensor and a second blood flow sensor, wherein the arithmetic circuit obtains a representative value of a first blood flow rate measured by the first blood flow sensor and a second blood flow rate measured by the second blood flow sensor, and wherein the arithmetic circuit calculates the delay time based on the representative value and the relation stored in the non-transitory memory.

5. The internal body temperature measurement device according to claim 1 , wherein the core temperature is a temperature of a core of the living body, and wherein the core of the living body is separated from the body surface by subcutaneous tissue.

6. The internal body temperature measurement device according to claim 1 , wherein the non-transitory memory which stores the relation between the plurality of different blood flow rates and the parameter stores the relation as a table correlating each of the plurality of different blood flow rates with the respective delay time.

7. The internal body temperature measurement device according to claim 1 , wherein the non-transitory memory which stores the relation between the plurality of different blood flow rates and the parameter stores the relation as a function correlating each of the plurality of different blood flow rates with the respective delay time, wherein blood flow rate is a variable of the function.

8. An internal body temperature measurement method comprising:
measuring, by a temperature sensor, an epidermis temperature of a living body;
measuring, by a heat flux sensor, a magnitude of a heat flux discharged from a body surface of the living body;
measuring, by a blood flow sensor, a blood flow rate of the living body; and
calculating a core temperature of the living body from the epidermis temperature and the magnitude of the heat flux;
calculating a delay time corresponding to the epidermis temperature measured by the temperature sensor by correlating the blood flow rate measured by the blood flow sensor and a relation between a plurality of different blood flow rates and a parameter, the parameter defining a respective delay time until a fluctuation of the core temperature of the living body is reflected on the epidermis temperature of the living body with each of the plurality of different blood flow rates; and
correcting a time corresponding to the core temperature of the living body based on the delay time, wherein correcting the time corresponding to the core temperature of the living body based on the delay time comprises correcting the time corresponding to the core temperature of the living body based on the delay time that is less than a predetermined threshold.

9. The method according to claim 8 , wherein the relation between the blood flow rate and the parameter was stored prior to calculating the delay time.

10. The method according to claim 8 , wherein the parameter is a time constant of a fluctuation of the epidermis temperature with respect to the fluctuation of the core temperature of the living body or the delay time.

11. The method according to claim 8 , wherein the core temperature is a temperature of a core of the living body, and wherein the core of the living body is separated from the body surface by subcutaneous tissue.

12. The method according to claim 8 , wherein the relation is stored as a table correlating each of the plurality of different blood flow rates with the respective delay time.

13. The method according to claim 8 , wherein the relation is stored as a function correlating each of the plurality of different blood flow rates with the respective delay time, wherein blood flow rate is a variable of the function.

Assignees

• Nippon Telegraph & Telephone

Inventors

• Seyama Michiko
• Matsunaga Daichi
• Tanaka Yujiro

Classifications

• G01K13/20 Primary

  Clinical contact thermometers for use with humans or animals · CPC title

• A61B5/01

  Measuring temperature of body parts {; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue} (clinical contact thermometers G01K13/20) · CPC title

• A61B5/026

  Measuring blood flow {(A61B3/1233, A61B3/1241 take precedence)} · CPC title

• G01K7/42

  Circuits effecting compensation of thermal inertia; Circuits for predicting the stationary value of a temperature · CPC title

• G01K17/20

  across a radiating surface, combined with ascertainment of the heat-transmission coefficient · CPC title