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Composition for preventing or treating dry eye syndrome, containing Aucuba japonica extract
US11938162B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11938162-B2 |
| Application number | US-201816965754-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 30, 2018 |
| Priority date | Jan 29, 2018 |
| Publication date | Mar 26, 2024 |
| Grant date | Mar 26, 2024 |
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- Title
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Abstract
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Provided is a composition for preventing, alleviating or treating dry eye syndrome, containing an Aucuba japonica extract as an active ingredient. The composition containing an Aucuba japonica extract can be effectively used in the prevention, alleviation or treatment of dry eye syndrome.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method for treating dry eye syndrome, comprising administering a therapeutically effective amount of an Aucuba japonica extract to a subject in need of treating the dry eye syndrome, wherein the Aucuba japonica extract comprises aucubin. 2. The method for treating dry eye syndrome according to claim 1 , wherein the Aucuba japonica extract is an ethanol extract or a hot water extract. 3. The method for treating dry eye syndrome according to claim 2 , wherein the ethanol extract is a 20-40% ethanol (w/w) extract. 4. The method for treating dry eye syndrome according to claim 2 , wherein the hot water extract is extracted at a temperature of 90-120° C. 5. The method for treating dry eye syndrome according to claim 1 , wherein the Aucuba japonica extract is administered orally. 6. The method for treating dry eye syndrome according to claim 1 , wherein the Aucuba japonica extract is an extract of the leaf or stem of Aucuba japonica. 7. A method for increasing tear secretion amount, comprising administering a therapeutically effective amount of an Aucuba japonica extract to a subject in need of increasing the tear secretion amount, wherein the Aucuba japonica extract comprises aucubin. 8. The method for increasing tear secretion amount according to claim 7 , wherein the Aucuba japonica extract is an ethanol extract or a hot water extract. 9. The method for increasing tear secretion amount according to claim 8 , wherein the ethanol extract is a 20-40% ethanol (w/w) extract. 10. The method for increasing tear secretion amount according to claim 8 , wherein the hot water extract is extracted at a temperature of 90-120° C. 11. The method for increasing tear secretion amount according to claim 7 , wherein the Aucuba japonica extract is administered orally. 12. The method for increasing tear secretion amount according to claim 7 , wherein the Aucuba japonica extract is an extract of the leaf or stem of Aucuba japonica. 13. A method for treating corneal morphological change, comprising administering a therapeutically effective amount of an Aucuba japonica extract to a subject in need of treating the corneal morphological change, wherein the Aucuba japonica extract comprises aucubin. 14. The method for treating corneal morphological change according to claim 13 , wherein the Aucuba japonica extract is an ethanol extract or a hot water extract. 15. The method for treating corneal morphological change according to claim 14 , wherein the ethanol extract is a 20-40% ethanol (w/w) extract. 16. The method for treating corneal morphological change according to claim 14 , wherein the hot water extract is extracted at a temperature of 90-120° C. 17. The method for treating corneal morphological change according to claim 13 , wherein the Aucuba japonica extract is administered orally. 18. The method for treating corneal morphological change according to claim 13 , wherein the Aucuba japonica extract is an extract of the leaf or stem of Aucuba japonica.
Assignees
Inventors
Classifications
- A61K36/54Primary
Lauraceae (Laurel family), e.g. cinnamon or sassafras · CPC title
Artificial tears; Irrigation solutions · CPC title
using water, e.g. cold water, infusion, tea, steam distillation or decoction · CPC title
- A61K36/40Primary
Cornaceae (Dogwood family) · CPC title
Ophthalmic agents · CPC title
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Frequently asked questions
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- What does patent US11938162B2 cover?
- Provided is a composition for preventing, alleviating or treating dry eye syndrome, containing an Aucuba japonica extract as an active ingredient. The composition containing an Aucuba japonica extract can be effectively used in the prevention, alleviation or treatment of dry eye syndrome.
- Who is the assignee on this patent?
- Nat Univ Chonbuk Ind Coop Found
- What technology area does this patent fall under?
- Primary CPC classification A61K36/54. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Mar 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).