Ablation systems with parameter-based modulation and related devices and methods

Patent metadata

Field	Value
Publication number	US-11937864-B2
Application number	US-201916677124-A
Country	US
Kind code	B2
Filing date	Nov 7, 2019
Priority date	Nov 8, 2018
Publication date	Mar 26, 2024
Grant date	Mar 26, 2024

Abstract

The invention relates to a magnetic-navigation joint type puncture needle which comprises a head section and needle sections, wherein, the head section is made of stainless steel material with high magnetic conductivity and is connected with the following needle sections coaxially mounted with the head section through a flexible joint; two needle sections are also coaxially connected with each other through a flexible joint; the needle sections are made of non-magnetic stainless steel material; the flexible joints adopts serpentine tubes formed by melting and engraving cobalt-chromium alloy through laser; and both the head section and the needle sections can be bent, but the flexibility of the head section and that of the needle sections are smaller than the flexibility of the flexible joints. According to the invention, an extra magnetic field force is used to cause the head section of the needle to deflect, so that the following purposes can be achieved that the insertion direction of the needle can be changed, and the other needle sections also deflect with the deflection of the head section; accurate navigation for and control over puncture path and puncture position when the puncture needle performs a non-direct channel puncture in a human body; the puncture needle provided by the invention can reach niduses which other types of puncture needles can not reach; the application scope of minimally invasive surgery is expanded; iatrogenic injuries can be reduced; and patients can be benefited.

First claim

We claim:

1. A system for tumor ablation, the system comprising:
a probe comprising:
a first conductor;
a second conductor disposed distal to the first conductor;
an insulator bushing disposed between the first conductor and the second conductor; and
a first thermocouple to measure a temperature at a location on the second conductor;
a second thermocouple on the second conductor;
a third thermocouple on the second conductor; and
a fourth thermocouple on the second conductor;

a generator to produce a current to be conducted between the first conductor and the second conductor to create an ablation region with a first potential ablation perimeter, and wherein the second thermocouple, the third thermocouple, and the fourth thermocouple respectively define a second point along a second potential ablation perimeter, a third point along a third potential ablation perimeter, and a fourth point along a fourth potential ablation perimeter, wherein each of the potential ablation perimeters is different;
a display; and
a processor to:
monitor the temperature at the first thermocouple;
monitor an impedance of the tissue between the first conductor and the second conductor;
control an output of the generator to decrease the current when the impedance increases and to stop the current when a thermal dose reaches a target threshold;
control the output of the generator based on a type of a procedure being performed; and
configure the display to provide a graphical user interface illustrating the first potential ablation perimeter, the second potential ablation perimeter, the third potential ablation perimeter, and the fourth potential ablation perimeter.

2. The system of claim 1 , wherein the graphical user interface receives size input from a user to specify which of the first potential ablation perimeter, the second potential ablation perimeter, the third potential ablation perimeter, and the fourth potential ablation perimeter is to be used to define the desired ablation region.

3. The system of claim 2 , wherein the display comprises a touchscreen, and wherein the size input is received via the touchscreen.

4. The system of claim 1 , wherein the graphical user interface superimposes one or more of the potential ablation perimeters on an image of the tissue.

5. The system of claim 1 , further comprising a fifth thermocouple on the first conductor.

6. The system of claim 5 , wherein the processor is further to control the generator based on temperature measurements of the first thermocouple and the fifth thermocouple.

7. The system of claim 1 , wherein the processor is further to receive manual ablation input from a user to selectively override impedance-based control of the generator, wherein the manual ablation input specifies a time period to apply a target power level.

8. The system of claim 1 , further comprising a display to provide a graphical user interface illustrating a mode selection that allows a user to switch between an automatic mode and a manual mode, wherein:
in the automatic mode, the generator is configured to automatically adjust the output of the generator based on one or more of the temperature at the first thermocouple or the impedance of the tissue, and
in the manual mode, the user determines the output of the generator.

9. A non-transitory computer-readable medium including instructions, that when executed by one or more processors of a tumor ablation system, cause the tumor ablation system to:
monitor temperature of tissue surrounding a probe via multiple thermocouples, the multiple thermocouples to measure temperature at different points along a length of the probe;
configure a display to provide a graphical user interface illustrating a first potential ablation zone, a second potential ablation zone, a third potential ablation zone, and a fourth potential ablation zone, wherein each of the potential ablation zones corresponds to one of the multiple thermocouples;
receive input from a user indicating a desired ablation region corresponding to one of the potential ablation zones;
determine a primary thermocouple by determining which of the multiple thermocouples is nearest an outer perimeter of the desired ablation region;
monitor an impedance of the tissue between a first conductor and a second conductor of the probe; and
adjust an output current of a generator, wherein the generator produces an electrical alternating current to be conducted between the first conductor and the second conductor via tissue within the desired ablation region, the output current to:
decrease when the impedance increases,
decrease when a maximum distal temperature is reached, and
stop when a thermal dose at the primary thermocouple reaches a target threshold, be based on a type of a procedure being performed, and
be based on a type of a procedure being performed.

10. The non-transitory computer-readable medium of claim 9 , wherein the instructions, when executed by the one or more processors, further cause the tumor ablation system to monitor a temperature at a distal portion of the probe via a distal thermocouple, wherein the output current is adjusted based on the temperature at the distal portion.

11. The non-transitory computer-readable medium of claim 9 , wherein the instructions, when executed by the one or more processors, further cause the tumor ablation system to superimpose the desired ablation region on an image of a tumor displayed in the graphical user interface.

12. The non-transitory computer-readable medium of claim 11 , wherein the image is a magnetic resonance imaging scan.

13. The non-transitory computer-readable medium of claim 9 , wherein adjusting the output current of the generator is based on user-defined parameters.

14. A system for tumor ablation, the system comprising:
a first probe comprising:
a first set of thermocouples to measure temperature at different points along the first probe, and
a first conductor and a second conductor;

a second probe comprising:
a second set of thermocouples to measure temperature at different points along the second probe, and
a third conductor and a fourth conductor;

a generator to provide a first current output to the first probe and a second current output to the second probe; and
a processor to:
monitor temperature measurements from the first set of thermocouples and the second set of thermocouples;
monitor a first impedance between the first conductor and the second conductor, and a second impedance between the third conductor and the fourth conductor;
monitor a third impedance between the first conductor and the third conductor; and
adjust the first current output and the second current output of the generator based on the first impedance, the second impedance, the third impedance, the temperature measurements, and a type of a procedure being performed.

15. The system of claim 14 , wherein the first current output is decreased when the first impedance increases, and the second current output is decreased when the second impedance increases.

16. The system of claim 14 , wherein the first current output is decreased when the first impedance increases and when the second impedance increases.

17. The system of claim 14 , wherein the first current output and the second current output are decreased when the third impedance increases.

18. The system of claim 14 , wherein:
the generator comprises:
a first port and a second port to couple with the first probe and the second probe, and
a first indicator light associated with the first port, and a se

Assignees

• Dfine Inc

Inventors

• Defosset Joshua
• Shirley Nate
• Wong Eric
• Purdy Craig
• Yurchak Oleg
• Chan Jimmy Chi-Yun
• Poser Robert D

Classifications

• A61B18/1477

  Needle-like probes · CPC title

• A61B18/14 Primary

  Probes or electrodes therefor · CPC title

• A61B18/1206

  Generators therefor · CPC title

• G06F3/0482

  Interaction with lists of selectable items, e.g. menus · CPC title

• G06F3/0488 Primary

  using a touch-screen or digitiser, e.g. input of commands through traced gestures · CPC title