Method of printing a tissue construct with embedded vasculature
US-2016287756-A1 · Oct 6, 2016 · US
US11931969B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11931969-B2 |
| Application number | US-201816603173-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 6, 2018 |
| Priority date | Apr 6, 2017 |
| Publication date | Mar 19, 2024 |
| Grant date | Mar 19, 2024 |
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
What the patent document calls the invention.
A short plain-language summary of the technical disclosure.
Who owns or filed the patent and who is credited as inventor.
Filing, priority, publication, and grant dates set the timeline.
The legal scope of protection — read this for what is actually claimed.
Technology tags used to group this patent with similar filings.
Prior art links and similar publications in this corpus.
Official abstract text for this publication.
This document describes systems and method of embedded printing for additive manufacturing. A print material is printed into a support material. The print material and the support material each have a fluid phase and a solid phase. The print material transitions from the fluid phase to the solid phase based on a fluid-fluid interaction with the support material. One or more parameters of the support material can be adjusted to cause a diffusion rate of the print material into the support material during the fluid-fluid interaction to be less than a threshold value. Multiple print materials can be printed into the support material simultaneously.
Opening claim text (preview).
What is claimed is: 1. A system comprising: a support material comprising a first solid phase and a first fluid phase, the support material being configured to flow in response to experiencing a mechanical stress; and a print material embedded within the support material, the print material configured to transition from a second fluid phase to a second solid phase within the support material by a fluid-fluid interaction between the first fluid phase of the support material and the second fluid phase of the print material; a buffering material having a predetermined concentration within the support material, the buffering material causing the transition of the print material from the second fluid phase to the second solid phase within the support material at a predetermined rate based on the predetermined concentration. 2. The system of claim 1 , wherein the support material is more basic than the print material, and wherein the print material is acidic, and wherein a transition of the support material comprises a neutralization of the print material during the fluid-fluid interaction of the print material and the support material. 3. The system of claim 1 , wherein the print material comprises at least one of collagen, gelatin, and alginate. 4. The system of claim 1 , wherein the print material comprises a strand including a diameter between about 10-250 micrometers. 5. The system of claim 1 , wherein the print material is a first print material, and wherein the system comprises a second print material that forms a mesh that encases the first print material, the mesh configured to support a geometry of the first print material when the support material is removed from the first print material. 6. The system of claim 5 , wherein the first print material comprises collagen, wherein the second print material comprises alginate, and wherein the support material comprises calcium. 7. The system of claim 1 , wherein the support material comprises a salt concentration that is configured to induce a gelation of the print material from the second fluid phase to the second solid phase in the support material. 8. The system of claim 7 , wherein the salt concentration of the support material is approximately 40 g/L-80 g/L. 9. The system of claim 1 , wherein the support material comprises a coacervate slurry.
Porous materials, {e.g. foams or sponges} · CPC title
containing added animal cells (organs or tissue containing native cells A61L27/36) · CPC title
Collagen · CPC title
using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material · CPC title
Gelatin · CPC title
Related publications grouped by family.
Answers are generated from the same data shown on this page.