Antimicrobial inserts for medical devices

Patent metadata

Field	Value
Publication number	US-11931483-B2
Application number	US-202017005133-A
Country	US
Kind code	B2
Filing date	Aug 27, 2020
Priority date	Feb 20, 2014
Publication date	Mar 19, 2024
Grant date	Mar 19, 2024

Abstract

Inserts can be formed with elution characteristics to cause the inserts to elute an antimicrobial agent when subject to a fluid within a medical device. An insert can be formed with a desired geometry to allow the insert to be compression fit within a medical device to prevent the insert from moving or becoming dislodged once inserted into the medical device. The material may also be hygroscopic so that the insert swells when subject to a fluid thereby enhancing the compression fit of the device within the medical device. In some cases, the material can be reinforced using an internal structure. Inserts can be formed in many ways including by casting, thermoforming, or extrusion. In some cases, the inserts can be formed using a peel-away sleeve or material. The peel-away sleeves can be formed of a non-sticky material which facilitates removal of the inserts once the inserts have cured.

First claim

The invention claimed is:

1. A method for forming an insert for a medical device, the method comprising:
combining a base material having elution characteristics with an antimicrobial agent to form a base material matrix; and
forming the base material matrix into a tubular insert that is sized and shaped to be contained within a catheter adapter;
inserting the tubular insert into a lumen of a catheter adapter, wherein the tubular insert comprises an opening therethrough such that the tubular insert is configured for fluid to flow therethrough; and
inserting a septum into the catheter adapter.

2. The method of claim 1 , wherein the base material matrix is formed into the tubular insert using one of: UV curing, heat curing, or heat forming.

3. The method of claim 1 , wherein forming the base material matrix into the tubular insert comprises placing the base material matrix within a peel-away material.

4. The method of claim 1 , further comprising:
placing the tubular insert within the medical device such that the tubular insert is exposed to a fluid to cause the antimicrobial agent to elute from the tubular insert into the fluid.

Assignees

• Becton Dickinson Co

Inventors

• Shevgoor Siddarth K
• Burkholz Jonathan Karl
• Liu Huibin
• Ma Yiping
• Zhou Ming

Classifications

• A61L29/16 Primary

  Biologically active materials, e.g. therapeutic substances {(A61L29/048 takes precedence)} · CPC title

• A61L29/06

  obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds · CPC title

• A61L29/126

  having a macromolecular matrix · CPC title

• A61L29/14

  Materials characterised by their function or physical properties {, e.g. lubricating compositions} · CPC title

• A61M25/0009

  Making of catheters or other medical or surgical tubes · CPC title