Medical devices for agent delivery and related methods of use

Patent metadata

Field	Value
Publication number	US-11931003-B2
Application number	US-202017109510-A
Country	US
Kind code	B2
Filing date	Dec 2, 2020
Priority date	Dec 3, 2019
Publication date	Mar 19, 2024
Grant date	Mar 19, 2024

Abstract

A delivery device may be configured to deliver an agent to a target tissue through a channel of a medical device, the delivery device may include a body including (a) a coupling region configured to removably attach to a handle of the medical device, and (b) a coupler including an exit port for aligning with a port of the channel, wherein the coupler is configured to mate with the port of the channel; a source of an agent; and a source of pressurized fluid. The body, the source of agent, and the source of pressurized fluid may be arranged to deliver agent and pressurized fluid to the exit port for delivery through the channel.

First claim

We claim:

1. A delivery device configured to deliver an agent to a target tissue through a channel of a medical device, the delivery device comprising:
a body including (a) a coupling region configured to removably attach to a handle of the medical device, the medical device including an endoscope, and (b) a coupler including an exit port for aligning with a port of the channel, wherein the coupler is configured to mate with the port of the channel;
a source of the agent defined by a cylindrical portion and a funnel portion positioned downstream from the cylindrical portion, the cylindrical portion is configured to store the agent and the funnel portion is configured to receive the agent from the cylindrical portion via gravity;
a source of pressurized fluid disposed within the body, the cylindrical portion is in fluid communication with the source of pressurized fluid through the funnel portion; and
an actuator including a trigger that is movably coupled to the body, wherein, in response to pulling the actuator, the body, the source of the agent, and the source of pressurized fluid are arranged to deliver the pressurized fluid through the funnel portion upstream into the cylindrical portion of the source of agent to move the agent therein, and to move a mixture of the agent and the pressurized fluid out of the source of the agent and to the exit port for delivery through the channel;
wherein the actuator is configured to move a pin relative to the body and into engagement with the source of pressurized fluid, in response to selectively pulling the actuator, thereby piercing the source of pressurized fluid and releasing the pressurized fluid into the source of the agent.

2. The device according to claim 1 , wherein the coupling region is configured to mate with the handle of the medical device.

3. The device according to claim 1 , wherein the coupling region includes features configured to inhibit movement between the coupling region and the handle of the medical device.

4. The device according to claim 1 , wherein the coupling region is configured to snap-fit onto the handle of the medical device.

5. The device according to claim 1 , wherein the coupling region is configured to wrap around the handle of the medical device.

6. The device according to claim 1 , wherein the handle of the medical device is a first handle, and wherein the body includes a second handle, the actuator is movably coupled to the second handle.

7. The device according to claim 6 , wherein the second handle includes an interior portion configured to receive a pressurized fluid container, the pressurized fluid container including the source of pressurized fluid.

8. The device according to claim 6 , wherein a longitudinal axis of the second handle extends substantially parallel to a longitudinal axis of the first handle when the delivery device is coupled to the first handle.

9. The device according to claim 6 , wherein the second handle is spaced from the first handle when the delivery device is coupled to the first handle.

10. The device according to claim 1 , wherein the coupler is configured to form a fluid tight seal with the port of the channel such that the exit port is fluidically connected to the channel.

11. The device according to claim 1 , wherein the coupler is a press-fit coupler configured to press fit onto the port to form a fluid tight seal with the port.

12. The device according to claim 1 , wherein the coupler is a first coupler and the exit port is a first exit port, and further comprising:
a first catheter fluidically coupled to the first coupler at a first end;
a y-connector fluidically coupled to a second end of the first catheter;
a syringe fluidically coupled to the y-connector; and
a second coupler including a second exit port for aligning with a port of the channel; wherein the second exit port is fluidically connected to the first catheter, the y-connector, and the syringe; and wherein the second coupler is configured to mate with the port of the channel.

13. The device according to claim 12 , further comprising a second catheter including a third coupler, wherein the second catheter is fluidically connected to the y-connector, coupled to the second coupler, and the third coupler is configured to mate with the port of the channel.

14. The device according to claim 1 , wherein the handle of the medical device is a first handle, and wherein the body includes a first proximal portion including a second handle, a first distal portion, and a second proximal portion including the coupling region.

15. A delivery device configured to deliver an agent to a target tissue through a channel of a medical device, the delivery device comprising:
a body including (a) a coupling region configured to removably attach to a handle of the medical device, the medical device including an endoscope, and (b) a coupler including an exit port for aligning with a port of the channel, wherein the coupler is configured to mate with the port of the channel;
a pressurized fluid container within the body;
an enclosure within the body defined by a cylindrical portion and a funnel portion positioned at an end of the enclosure opposite to the cylindrical portion, and wherein the cylindrical portion is configured to store and feed the agent to the funnel portion via gravity, the funnel portion is configured to receive a pressurized fluid to move the agent within the cylindrical portion of the enclosure, and to direct and release a combination of the pressurized fluid and the agent through the exit port;
a regulator within the body and configured to control delivery of the pressurized fluid from the pressurized fluid container prior to the pressurized fluid entering the enclosure at the funnel portion, the regulator including a fluid input port coupled to the pressurized fluid container such that the pressurized fluid enters the regulator prior to entering the enclosure, wherein the pressurized fluid and the agent flows from the enclosure to the exit port upon the pressurized fluid from the pressurized fluid container entering the regulator via the fluid input port and prior to the cylindrical portion of the enclosure receiving the pressurized fluid from the regulator via the funnel portion; and
an actuator including a trigger, the actuator configured to pierce the pressurized fluid container by selectively moving a pin into engagement with the pressurized fluid container to release the pressurized fluid from the pressurized fluid container for receipt by the regulator via the fluid input port.

16. The delivery device according to claim 15 , wherein a total volume of the pressurized fluid within the pressurized fluid container is configured to deploy a preset amount of the agent through the channel, and the agent includes a powder.

17. A system configured to deliver an agent to a target tissue through a channel of a medical device, the system comprising:
the medical device comprising an endoscope that includes a handle, the channel, and a port at an end of the channel; and
a delivery device comprising:
a body including (a) a coupling region configured to removably attach to the handle; and (b) a coupler including an exit port for aligning with the port, wherein the coupler is configured to mate with the port;
an input port disposed within the body;
a source of the agent disposed within the body, the source of the agent is defined by a funnel portion and a cylindrical portion positioned upstream from the funnel portion, the cylindrical portion is configured to feed the agent to the funnel portion via gravity,

Assignees

• Boston Scient Scimed Inc

Inventors

• Congdon Daniel
• Smith Amanda Lynn
• Lehtinen Laurie A
• Pic Andrew
• Weiner Jason

Classifications

• A61B1/0014 Primary

  Fastening element for attaching accessories to the outside of an endoscope, e.g. clips, clamps or bands · CPC title

• A61B1/00073

  with externally grooved shaft · CPC title

• A61B1/00119

  Tubes or pipes in or with an endoscope · CPC title

• A61B1/00128

  mechanical, e.g. for tubes or pipes · CPC title

• A61B1/00137

  End pieces at either end of the endoscope, e.g. caps, seals or forceps plugs · CPC title