Methods for extracting compound from ginseng, ginseng extract comprising the compound and composition for enhancing skin barrier comprising the same

Patent metadata

Field	Value
Publication number	US-11925702-B2
Application number	US-202318169522-A
Country	US
Kind code	B2
Filing date	Feb 15, 2023
Priority date	May 31, 2022
Publication date	Mar 12, 2024
Grant date	Mar 12, 2024

Abstract

Disclosed are a method for extracting a compound represented by Chemical Formula 1 from ginseng, including anaerobic natural fermentation of ginseng, an anaerobic-naturally fermented ginseng extract including the compound represented by Chemical Formula 1 extracted by the method, and a method of enhancing the skin barrier including applying a composition including an effective amount of the anaerobic-naturally fermented ginseng extract.

In Chemical Formula 1, each substituent is as defined in the specification.

First claim

What is claimed is:

1. A method for extracting a compound of Chemical Formula 1-1 from ginseng, comprising:
anaerobic natural fermentation of ginseng without an inoculation of microorganisms,

wherein the ginseng is subjected to rolling.

2. The method of claim 1 , wherein
the natural fermentation is fermentation for about 15 days to about 30 days at about 35° C. to about 65° C.

3. The method of claim 1 , wherein
the natural fermentation is fermentation of the ginseng in a sealed state.

4. The method of claim 1 , wherein
the rolling is performed for about 20 minutes to about 60 minutes.

5. The method of claim 1 , wherein
the method includes:
washing ginseng;
rolling the washed ginseng;
cutting and/or crushing the rolled ginseng;
naturally fermenting the cut and/or crushed ginseng without inoculating microorganisms;
drying the naturally fermented ginseng; and
extracting the dried naturally fermented ginseng to obtain an extract containing the compound of Chemical Formula 1-1.

6. The method of claim 1 , wherein
the ginseng includes fresh ginseng.

Assignees

• Amorepacific Corp

Inventors

• Kim Dong Hyun
• Kim Sehyun
• Kim Hyunsoo
• Shin Misook
• Lee Seung Jo

Classifications

• A61K8/9789 Primary

  Magnoliopsida [dicotyledons] · CPC title

• A61Q19/00

  Preparations for care of the skin · CPC title

• A61K2800/85

  Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine · CPC title

• C12P33/20 Primary

  containing heterocyclic rings · CPC title

• A61K8/63

  Steroids; Derivatives thereof · CPC title