Methods and systems for spin-echo train imaging using spiral rings with retraced trajectories

Patent metadata

Field	Value
Publication number	US-11921179-B2
Application number	US-202217732181-A
Country	US
Kind code	B2
Filing date	Apr 28, 2022
Priority date	Apr 28, 2021
Publication date	Mar 5, 2024
Grant date	Mar 5, 2024

Abstract

Methods, computing devices, and magnetic resonance imaging systems that improve image quality in turbo spiral echo (TSE) imaging are disclosed. With this technology, a TSE pulse sequence is generated that includes a series of radio frequency (RF) refocusing pulses to produce a corresponding series of nuclear magnetic resonance (NMR) spin echo signals. A gradient waveform including a plurality of segments is generated. The plurality of segments collectively comprise a spiral ring retraced in-out trajectory. During an interval adjacent to each of the series of RF refocusing pulses, a first gradient pulse is generated according to the gradient waveform. The first gradient pulses encode the NMR spin echo signals. An image is then constructed from digitized samples of the NMR spin echo signals obtained based at least in part on the encoding.

First claim

What is claimed is:

1. A method for turbo spiral echo (TSE) imaging of a subject, the method implemented by one or more computing devices and comprising:
generating a TSE pulse sequence comprising a series of radio frequency (RF) refocusing pulses to produce a corresponding series of nuclear magnetic resonance (NMR) spin echo signals;
generating a gradient waveform comprising a first plurality of segments collectively comprising a spiral ring retraced in-out trajectory;
generating during an interval adjacent to each of the series of RF refocusing pulses a first gradient pulse according to the gradient waveform, wherein the first gradient pulses encode the NMR spin echo signals; and
constructing an image from digitized samples of the NMR spin echo signals obtained based at least in part on the encoding.

2. The method of claim 1 , wherein the first gradient pulses encode the NMR spin echo signals in a first gradient axis.

3. The method of claim 2 , further comprising generating during the interval adjacent to each of the series of RF refocusing pulses a second gradient pulse according to the gradient waveform, wherein the second gradient pulses encode the NMR spin echo signals in a second gradient axis different from the first gradient axis.

4. The method of claim 1 , wherein one of the first plurality of segments comprises self-retraced in-out rings, the self-retraced in-out rings are preceded by one or more spiral-in rings of the first plurality of segments, and the self-retraced in-out rings are followed by one or more spiral-out rings of the first plurality of segments.

5. The method of claim 4 , wherein a first one of the one or more spiral-out rings comprises a field map and the method further comprises using a semiautomatic deblurring based on the field map to construct the image.

6. The method of claim 1 , further comprising:
generating a RF excitation pulse to produce transverse magnetization that generates a NMR signal; and
constructing the image further based on a slice select gradient pulse generated concurrently with each of the RF refocusing pulses.

7. The method of claim 1 , further comprising:
inverting a gradient polarity of a first copy of a first one of a second plurality of segments of equal time duration split from a spiral-out ring;
inserting a time-reversed version of the first copy in front of the first one of the second plurality of segments to generate a self-retraced in-out ring;
inserting the remaining ones of the second plurality of segments consecutively at a first plurality of TSE echoes following the effective echo time to generate one or more spiral-out rings;
inverting another gradient polarity of a second copy of each of the remaining ones of the second plurality of segments; and
inserting the second copies consecutively in reverse order at a second plurality of TSE echoes preceding the effective echo time to generate one or more spiral-in rings.

8. The method of claim 7 , further comprising rotating a plurality of times the self-retraced in-out rings, the one or more spiral-out rings, and the one or more annular spiral-in rings to generate the first plurality of segments of the gradient waveform.

9. A computing device, comprising memory comprising programmed instructions stored thereon and one or more processors configured to execute the stored programmed instructions to:
produce a turbo spiral echo (TSE) pulse sequence to generate a corresponding series of nuclear magnetic resonance (NMR) spin echo signals, wherein the TSE pulse sequence comprises a series of radio frequency (RF) refocusing pulses;
generate first and second gradient waveforms each comprising a first plurality of segments collectively comprising a spiral ring retraced in-out trajectory;
generate during an interval adjacent to each of the series of RF refocusing pulses a pair of gradient pulses each according to one of the first or second gradient waveforms, wherein the pair of gradient pulses provides an encoding of the NMR spin echo signals; and
construct an image from digitized samples of the NMR spin echo signals obtained based in part on the encoding.

10. The computing device of claim 9 , wherein a first one of the pair of gradient pulses encode the NMR spin echo signals in a first gradient axis and a second one of the pair of gradient pulses encodes the NMR spin echo signals in a second gradient axis.

11. The computing device of claim 9 , wherein one of the first plurality of segments comprises self-retraced in-out rings, the self-retraced in-out rings are preceded by one or more spiral-in rings of the first plurality of segments, and the self-retraced in-out rings are followed by one or more spiral-out rings of the first plurality of segments.

12. The computing device of claim 11 , wherein a first one of the one or more spiral-out rings comprises a field map and the one or more processors are further configured to execute the stored programmed instructions to use a semiautomatic deblurring based on the field map to construct the image.

13. The computing device of claim 9 , wherein the one or more processors are further configured to execute the stored programmed instructions to:
generate a RF excitation pulse to produce transverse magnetization that generates a NMR signal; and
construct the image further based on a slice select gradient pulse generated concurrently with each of the RF refocusing pulses.

14. The computing device of claim 9 , wherein the one or more processors are further configured to execute the stored programmed instructions to instruct a control sequencer to communicate with:
a magnetic resonance imaging (MRI) subsystem of an MRI system to produce the TSE pulse sequence; and
a gradient subsystem of the MRI system to generate the pair of gradient pulses.

15. The computing device of claim 9 , wherein the one or more processors are further configured to execute the stored programmed instructions to:
invert a gradient polarity of a first copy of a first one of a second plurality of segments of equal time duration split from a spiral-out ring;
insert a time-reversed version of the first copy in front of the first one of the second plurality of segments to generate a self-retraced in-out ring;
insert the remaining ones of the second plurality of segments consecutively at a first plurality of TSE echoes following the effective echo time to generate one or more spiral-out rings;
invert another gradient polarity of a second copy of each of the remaining ones of the second plurality of segments; and
insert the second copies consecutively in reverse order at a second plurality of TSE echoes preceding the effective echo time to generate one or more spiral-in rings.

16. The computing device of claim 15 , wherein the one or more processors are further configured to execute the stored programmed instructions to rotate a plurality of times the self-retraced in-out rings, the one or more spiral-out rings, and the one or more spiral-in rings to generate the first plurality of segments of the gradient waveform.

17. A magnetic resonance imaging (MRI) system, comprising:
a control sequencer coupled to a gradient subsystem comprising gradient amplifiers and gradient coils and an MRI subsystem comprising a static z-axis magnet and one or more radio frequency (RF) coils; and
a data acquisition and display (DADC) device comprising memory comprising programmed instructions stored thereon and one or more processors configured to execute the stored programmed instructions to:
generate first and second gradient waveforms each comprising a plurality of s

Assignees

• Univ Virginia Patent Foundation

Inventors

• Wang Zhixing
• Allen Steven P
• Feng Xue
• Mugler Iii John P
• Meyer Craig H

Classifications

• G01R33/482 Primary

  using a Cartesian trajectory · CPC title

• G01R33/543

  Control of the operation of the MR system, e.g. setting of acquisition parameters prior to or during MR data acquisition, dynamic shimming, use of one or more scout images for scan plane prescription (G01R33/546 takes precedence) · CPC title

• G01R33/5608

  Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels (image data processing or generation, in general G06T) · CPC title

• G01R33/5617

  using RF refocusing, e.g. RARE · CPC title

• G01R33/56509

  due to motion, displacement or flow, e.g. gradient moment nulling (G01R33/567 takes precedence) · CPC title