Active substance applicator for a joint implant, and joint implant having an active substance applicator

Patent metadata

Field	Value
Publication number	US-11911275-B2
Application number	US-201917041351-A
Country	US
Kind code	B2
Filing date	Mar 19, 2019
Priority date	Mar 26, 2018
Publication date	Feb 27, 2024
Grant date	Feb 27, 2024

Abstract

The present invention provides an active substance application insert (10, 110) for an implant (30), in particular a joint implant. The active substance application insert has a main body (11), an active substance chamber (12) formed in the main body, an application side (13, 113) which forms a front face of the active substance chamber, wherein the application side has a plurality of application openings (14, 114), and a securing means (15) with which the main body can be detachably secured in the implant. In a state in which the main body is inserted into the implant, the application side faces outwards relative to the implant, such that the application openings connect the active substance chamber to the environment of the implant. Furthermore, within the scope of the present invention an implant (30) with a recess (31) for receiving an active substance application insert (10, 110) is provided.

First claim

The invention claimed is:

1. An active substance application insert for an implant, comprising:
a main body,
an active substance chamber formed in the main body,
a peripheral active substance wall that extends around a perimeter of the active substance chamber,
an application side which forms a front face of the active substance chamber, wherein the application side faces bone tissue or soft tissue and has a plurality of application openings, and
a securing means configured to detachably secure the main body in the implant,
wherein in a state in which the main body is inserted into the implant, the application side faces outwards relative to the implant, such that the application openings connect the active substance chamber to the environment outside of the implant when the implant is implanted in a body of a patient,
wherein on the side opposite the application side a rear wall is formed, which forms a rear face of the active substance chamber and which faces the implant in the inserted state,
wherein at least one section of the rear wall on the rear face of the active substance chamber is formed by a reclosable cover,
wherein the main body has a peripheral outer wall between the front face and the rear face, which extends around a perimeter of the active substance application insert, and
wherein at least one section of the peripheral active substance wall between the application side and the rear face of the active substance chamber is formed separately from and inside the peripheral outer wall of the main body, such that an annular gap is formed along this section between the peripheral outer wall of the main body and the peripheral active substance wall.

2. The active substance application insert according to claim 1 , wherein
the securing means is formed by at least one section of the outer side of the peripheral outer wall forming a friction surface.

3. The active substance application insert according to claim 1 ,
wherein the peripheral outer wall forms at least one section of the peripheral active substance chamber wall between the application side and the rear face of the active substance chamber.

4. The active substance application insert according to claim 1 , wherein
the application side is provided with a tool-engaging means for inserting and/or removing the active substance application insert.

5. The active substance application insert according to claim 1 , wherein the application side has at least 4, 6, 8 or 10 and a maximum of 30 application openings.

6. The active substance application insert of claim 5 , in which the application openings are distributed evenly over the application side.

7. The active substance application insert according to claim 1 , wherein
the application openings have a minimum size of 0.5 mm or 1 mm and a maximum size of 2 mm, 3 mm or 4 mm.

8. The active substance application insert according to claim 1 , wherein the application openings are circular, oval, rectangular and/or slit-shaped.

9. The active substance application insert according to claim 1 , having at least one active substance in the form of a solid, beads, a granulate and/or a gel, which fills the active substance chamber at least in part.

10. The active substance application insert according to claim 9 , having an active substance that is an antibiotic.

11. An implant system, the implant system comprising:
an implant; and
an active substance application insert, wherein the implant comprises a cavity corresponding to a shape of the active substance application insert, the active substance application insert comprising:
a main body,
an active substance chamber formed in the main body, wherein the active substance chamber is arranged inside a peripheral outer wall,
a peripheral active substance wall that extends around a perimeter of the active substance chamber,
an application side which forms a front face of the active substance chamber, wherein the application side faces bone tissue or soft tissue and has a plurality of application openings, and
a securing means configured to detachably secure the main body in the implant,
wherein in a state in which the main body is inserted into the implant, the peripheral outer wall contacts a periphery of the cavity and the front face is coplanar with a surface of the implant,
and in the state in which the main body is inserted into the implant, the application side faces outwards relative to the implant, such that the application openings connect the active substance chamber to the environment outside of the implant when the implant is implanted in a body of a patient,
wherein the peripheral outer wall is between the front face and a rear face of the active substance chamber, which extends around a perimeter of the active substance application insert, and
wherein at least one section of the peripheral active substance wall between the application side and the rear face of the active substance chamber is formed separately from and inside the peripheral outer wall of the main body, such that an annular gap is formed along this section between the peripheral outer wall of the main body and the peripheral active substance wall.

12. The implant system according to claim 11 , wherein
the securing means is formed by at least one section of the outer side of the peripheral outer wall forming a friction surface.

13. The implant system according to claim 11 ,
wherein the peripheral outer wall forms at least one section of a peripheral active substance chamber wall between the application side and the rear face of the active substance chamber.

14. The implant system according to claim 11 , wherein
the application side is provided with a tool-engaging means for inserting and/or removing the active substance application insert.

Assignees

• Link Waldemar Gmbh Co

Inventors

• Capanna Rodolfo
• Link Helmut D

Classifications

• A61F2/30721 Primary

  Accessories · CPC title

• A61L27/54 Primary

  Biologically active materials, e.g. therapeutic substances {(A61L27/227 takes precedence)} · CPC title

• A61F2002/30331

  made by longitudinally pushing a protrusion into a complementarily-shaped recess, e.g. held by friction fit · CPC title

• A61F2002/3068

  the pharmaceutical product being in a reservoir · CPC title

• A61F2/3859

  Femoral components · CPC title