Leave-on oral care compositions

Patent metadata

Field	Value
Publication number	US-11904041-B2
Application number	US-202016899834-A
Country	US
Kind code	B2
Filing date	Jun 12, 2020
Priority date	Jun 14, 2019
Publication date	Feb 20, 2024
Grant date	Feb 20, 2024

Abstract

Leave-on oral care compositions comprising a hyaluronic acid or a salt thereof having good spreadability and improved retention period are provided for promoting Gum Health of a user.

First claim

What is claimed is:

1. An oral care composition comprising:
(a) from about 0.2% to about 2%, by weight of the oral care composition, of a hyaluronic acid or a salt thereof, wherein the hyaluronic acid has a weight average molecular weight of from about 900,000 Daltons to about 2,000,000 Daltons,
(b) from about 0.1% to about 5%, by weight of the composition, of a polyacrylic acid, and
(c) a total water content of from 30% to 65%, by weight of the composition,
wherein the composition has a Viscosity Consistency Coefficient K of from about 50 Pa·s to about 250 Pa·s as measured at 22° C. at a shear rate range of 0.1-10s −1 ,
wherein the oral care composition has a Mucoadhesion Index of no less than about 0 . 6 Fluorescent Intensity Percentage (“FI%”), and
wherein the oral care composition is a leave-on gel.

2. The oral care composition according to claim 1 , wherein the Viscosity Consistency Coefficient K is from about 50 Pa·s to about 200 Pa·s.

3. The oral care composition according to claim 1 , wherein the Mucoadhesion Index is no less than about 0.8 FI%.

4. The oral care composition according to claim 1 , further comprising an additional polymer, wherein the additional polymer is selected from the group consisting of xanthan gum, carrageenan, carboxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxymethyl cellulose, polyvinyl pyrrolidine, co-polymers of maleic anhydride with methyl vinyl ether having a weight average molecular weight of about 30,000 Daltons to about 1,000,000 Daltons, and combinations thereof; wherein the additional polymer is present in an amount of from about 0.1% to about 10%, by weight of the composition.

5. The oral care composition according to claim 1 , wherein the oral care composition is substantially free of abrasives.

6. The oral care composition according to claim 1 , further comprising a vitamin, wherein the vitamin is selected from the group consisting of Vitamin C, Vitamin E, Vitamin B5, and combinations thereof.

7. A method of improving Gum Health of a subject, the method comprising the steps of applying the oral care composition of claim 1 onto intraoral tissue of the subject, and leaving the oral care composition on the intraoral tissue without removal for a duration of time from about 1 minute to about 1000 minutes; and optionally wherein the applying step is the last step of an oral hygiene regimen.

8. The method of claim 7 , wherein the oral care composition is applied to intraoral tissue with an applicator comprising a handle and a head to spread the oral care composition onto the intraoral tissue of the subject.

9. A method of improving Gum Health of a subject, the method comprising the steps of:
(a) brushing teeth of the subject with an antibacterial toothpaste; and
(b) subsequently, applying the oral care composition of claim 1 onto intraoral tissue of the subject, and leaving the oral care composition on the intraoral tissue without removal for a duration of time of at least about 2 minutes.

10. The method of claim 9 , wherein the oral care composition is applied to intraoral tissue with an applicator comprising a handle and a head to spread the oral care composition onto the intraoral tissue of the subject.

11. A kit comprising a toothpaste and the oral care composition according to claim 1 .

12. A kit comprising the oral care composition according to claim 1 , and a delivery carrier for applying the oral care composition to intraoral tissue, wherein the delivery carrier comprises strip, film of material, dental tray, aligner, sponge material, applicator, or mixtures thereof.

Assignees

• Procter & Gamble

Inventors

• Strand Ross
• Su Yang
• Shi Yunming
• Shanmugam Thanigaivel
• Li Xiaowei
• Wang Guannan

Classifications

• A61K8/735 Primary

  Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof · CPC title

• A61C19/063

  Medicament applicators for teeth or gums, e.g. treatment with fluorides · CPC title

• A61K8/673

  Vitamin B group · CPC title

• A61K8/676

  Ascorbic acid, i.e. vitamin C · CPC title

• A61K8/678

  Tocopherol, i.e. vitamin E · CPC title